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in creator/contributor: "Goven, Arthur James, 1950-"

open access

Effects of Copper on Immune Responses of Largemouth Bass, Micropterus salmoides

Copper exposures of 400 μg/L for 5,10 and 15 days resulted in no significant differences in antibody titers of largemouth bass, Micropterus salmoides injected with Aeromonas hydrophila compared to control-injected bass. Twenty days of exposure did significantly increase titers. The control group had significantly lower antibody titers than either control-injected or copper-exposed.

Date: August 1994

Creator: Connell, Patrice M. (Patrice Michelle)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Construction of a Physical Map of Moraxella (Branhamella) catarrhalis Strain ATCC25238

In order to gain a better understanding of this microorganismand its role in human pathogenesis, a physical map of Moraxella catarrhalis type strain ATCC25238 was constructed using pulsed field gel electrophoresis (PFGE) in combination with Southern hybridization techniques. Restriction endonucleases Not I, Rsr II, and Sma I were used to digest the chromosomal DNA. An overlapping circular map was generated by cross-hybridization of isolated radiolabeled fragments of Moraxella catarrhalis genomi… more

Date: May 1999

Creator: Nguyen, Kim Thuy

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Enzyme Assays Using Earthworms for Assessing Innate and Nonspecific Immunotoxicity of Xenobiotics

Principal objectives of my research were to: (1) report for the first time that coelomocytes are able to reduce NBT dye and confirm the presence of lysozyme-like activity in earthworm; (2) develop a standard methodology for determination of NBT reduction and lysozyme-like activity in earthworms; (3) compare NBT reduction and lysozyme-like activity in earthworms with those of murine and human cells and fluids; and (4) demonstrate the sensitivity of earthworm NBT reduction and lysozyme-like activ… more

Date: May 1992

Creator: Chen, Shing-Chong

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Regulatory Divergence of Aspartate Transcarbamoylase from the Pseudomonads

Aspartate transcarbamoylase (ATCase) was purified from 16 selected bacterial species including existing Pseudomonas species and former species reassigned to new genera. An enormous diversity was seen among the 16 enzymes with each class of ATCase being represented. The smallest class, class C, with a catalytically active homotrimer, at 100 kDa, was found in Bacillus and other Gram positive bacteria. In this report, the ATCases from the Gram negatives, Shewanella putrefaciens and Stenotrophomona… more

Date: December 1996

Creator: Linscott, Andrea J. (Andrea Jane)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Effects of Acute and Chronic Glycemic Control on Memory Performance in Persons with Type II Diabetes Mellitus

Memory performance was measured in 48 persons between the ages of 40 - 65 with Type II diabetes. Correlations between performance on the California Verbal Learning Test, tests of Working Memory, Priming Memory, and Prospective Memory and several predictor variables were examined. These variables included the Slosson Intelligence Test Scores, demographic variables, presence of diabetic complications, finger-stick and HbA1c measures. Subjects performed worse than the normative sample on the Calif… more

Date: August 1995

Creator: Hall-Johnson, Richard Earl

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Effect of Cell-Specific, Music-Mediated Mental Imagery on Secretory Immunoglobulin A (sIgA)

This study was an investigation of the effects of physiologically-oriented mental imagery on immune functioning. College students with normal medical histories were randomly selected to one of three groups. Subjects in Group 1 participated in short educational training on the production of secretory immunoglobulin A. They were then tested on salivary IgA, skin temperature and the Profile of Mood States (POMS) before and after listening to a 17-minute tape of imagery instructions with specially-… more

Date: August 1988

Creator: Rider, Mark Sterling

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Biofeedback-Assisted Relaxation: Effects on Phagocytic Immune Functioning

Life events and one's ability to adapt to these events has significant effects on immune functioning. Immunosuppression has been related to a high magnitude of life stress and low adaptive ability. While studies have explored immune response in stressed individuals, no study has approached the area of prevention with low-immunity individuals. The purpose of this study was to investigate whether subjects who self-report stressful lives have lower immunity, and whether "low" immunity subjects und… more

Date: December 1982

Creator: Peavey, Barbara Suzanne

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Radial Compression High Performance Liquid Chromatography as a Tool for The Measurement of Endogenous Nucleotides in Bacteria

High performance liquid chromatography was used to measure ribonucleoside triphosphates in microbial samples. Anion exchange columns in a radial compression module were used to separate and quantify purine and pyrimidine ribonucleotides. Endogenous ribonucleoside triphosphates were extracted from Escherichia coli and pseudomonas aeruginosa using three different solvents, namely trifluorocetic acid (TFA; 0.5M), trichloroacetic acid (TCA; 6 per cent w/v) and formic acid (1.0M) Extracts were assay… more

Date: August 1986

Creator: Dutta, Probir Kumar

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Systematics of Coccidian Parasites (Apicomplexa) from Amphibians and Reptiles in Northcentral Texas

Between February 1986 and October 1988, 863 amphibians and reptiles were collected in northcentral Texas and examined for coccidial parasites. Thirteen percent of amphibians <26% salamanders, 11% frogs and toads) and 28% of reptiles (54% turtles, 25% snakes) harbored 20 previously described and 16 new species of coccidia; overall prevalence of infection was 176/863 < 20%). Sixteen Ambvstoma texanum were infected with Eimeria ambystomae which represents new host and geographic locality records f… more

Date: December 1989

Creator: McAllister, Chris Thomas

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

The Eosinophil and Lysophospholipase Responses in Mice Infected with Trichinella spiralis: A Role for the Lymphocyte and Macrophage

The relationship among eosinophils, lysophospholipase activity and the immune response in animals infected with Trichinella spiralis was studied using in vivo and in vitro techniques. In an in vivo experiment, anti-thymocyte serum (ATS) was administered to mice infected with T. spiralis and its effects on intestinal lysophospholipase (EC 3.1.1.5.) activity, peripheral blood, bone marrow and intestinal eosinophilia were measured in the same experimental animal. The ATS caused a significant tempo… more

Date: August 1986

Creator: Adewusi, Iyabode Olukemi, 1958-

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

The Genetics of Pigmentation in Corynebacterium poinsettiae ATCC 9682

Corynebacterium poinsettiae mutant strains blocked in carotenoid biosynthesis were obtained by treatment with the mutagen N-methyl-N1-nitro-N-nitrosoguanidine. Additional carotenoid (Crt) mutant strains were obtained from a previous study conducted in our laboratory. Fifty-nine Crt mutants affected in carotenoid biosynthesis were examined by a normal phase high performance liquid chromatography (HPLC) system. Pigment extracts of Crt mutants and C. poinsettiae wild type strains were resolved by … more

Date: August 1986

Creator: Campbell, Alan L. (Alan Lee)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Relationship of Self-esteem in Pediatric Burn Patients to other Psychological and Physiological Parameters

The purpose of this study was to evaluate post-burn adjustment in light of the self-esteem of child burn survivors. The study attempted to assess the viability of using a single, explicit self-report measure of self-esteem (Piers-Harris Children's Self-Concept Scale) as an index of post-burn adjustment. It appears that pediatric burn patients do not suffer a compromised self-concept secondary to the burn injury and, rather, are successful in incorporating their post-burn state, physically and p… more

Date: August 1992

Creator: Koon, Kamela Suzanne

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Effects of Trichinella Soluble Antigens on Macrophage Subpopulations

The immunomodulatory effects of Trichinella spiralis or Trichinella pseudospiralis soluble antigen extracts were examined in an effort to characterize the differences in immune responses seen during these Trichinella infections. The newborn larvae extracts of either parasite exhibited similar potency for stimulating macrophage PGE production; however, the muscle larvae extracts of T. pseudospiralis stimulated greater levels of PGE than did the muscle larvae extracts of T. spiralis. These data c… more

Date: August 1992

Creator: Dixon, Guy Cameron, 1960-

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Toxicity of Polychlorinated Biphenyls (Aroclor 1254) on the Earthworm Eisenia foetida

Objectives were to: (1) assess toxicity of polychlorinated biphenyls on Eisenia foetida, in terms of survival (LC5O/LD5O), and suppression of coelomocytes to form secretory (SR) and erythrocyte rosettes (ER) with, and to phagocytize rabbit erythrocytes; and (2) compare results with those of Lumbricus terrestris to assess relative sensitivities to PCB. Using 5-d filter paper contact exposure protocol, LC50 and LD50 were 30.4 cg/cm2 and 4450 cg/g dry mass, respectively. Nominal PCB exposure conce… more

Date: August 1991

Creator: Sassani, Ramin

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Effects of Gold Sodium Thiomalate on Murine Spleen Cells

The effects of gold sodium thiomalate (GST) on murine spleen cells were investigated using in vitro mitogen blastogenesis techniques. Addition of GST to intact spleen cells resulted in a decreased blastogenic response to the T cell mitogen, concanavalin A (Con A). Thymidine uptake of spleen cells depleted of macrophages and cultured with Con A and GST demonstrated biphasic effects. At 2.5 pg Con A/ml, blastogenesis of macrophage depleted spleen cells was inhibited to a lesser degree than intact… more

Date: December 1986

Creator: Brownback, Paul (Paul Eldon)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

The Effects of Long Term Modernate Ethanol Intake on Plasma Levels of ACTH, Beta Endorphin, and Corticosterone in Rats

The effects of single injections and daily oral administration of ethanol on plasma levels of ACTH, beta endorphin, and corticosterone in response to cold stress were examined. The long-term experimental animals were given 0.25 ml of 28% ethanol or water orally once a day, five days a week, for fourteen months. Plasma levels of ACTH, beta endorphin, and corticosterone were lower in alcohol-treated rats as compared with water-treated rats when exposed to cold stress. The effects of a single inje… more

Date: December 1990

Creator: Breedlove, Kenneth

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

The Effect of Examination Stress on Phagocytic Immune Functioning

The purpose of this study was to determine whether psychological stress, specifically examination stress, would decrease immune system functioning. Twenty-five first-year master's and doctoral students who volunteered to participate in the study were psychologically and immunologically assessed during two high- and two low-stress periods. Immunological assessments included a white blood cell differential count and nitroblue tetrazolium test (NBT) to measure neutrophil functioning. Psychologica… more

Date: December 1985

Creator: Didriksen, Nancy A. (Nancy Andrews)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Comparative Toxicity Responses in Earthworms Lumbricus Terrestris and Eisenia Foetida to Cadmium Nitrate and Chlordane Using Artificial Soil and Filter Paper Exposures

This research compares LC50 and LD50 of earthworms, Lumbricus terrestris and Eisenia foetida exposed to cadmium nitrate and chlordane using 48-h contact filter paper (FP) and 14-d artificial soil (AS) protocols. Both LC50 and LD50 showed that chlordane was more toxic than cadmium in both species regardless of the exposure. The reference toxicant 2-chloroacetamide using the standardized 48-h FP exposure was used to assess the general response of the earthworm prior to toxicity experiments. A glu… more

Date: August 1992

Creator: Muratti Ortiz, Joseph F.

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

The Response of Elderly People to a B-6 Supplement

Vitamin B-6 status was examined in a group of 46 elderly subjects who were selected from nursing home residents, hospital patients, and free living individuals in Denton County. Subjects were limited to men and women over 60 years of age. Erythrocyte aspartate aminotransferase stimulation with pyridoxal phosphate (in-vitro) was studied as the biochemical criterion of vitamin B-6 status. The pyridoxine status of these 46 subjects (the reference group) was measured in order to be able to identify… more

Date: August 1985

Creator: Chaomuangbon, Sunthorn

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

The Role of Anger/Hostility on Physiological and Behavioral Risk Factors for Coronary Heart Disease

The purpose of this study was to examine the role of anger/hostility on physiological and behavioral coronary heart disease risk factors. It was hypothesized that anger/hostility would contribute to the severity of CHD via consummatory behaviors such as smoking, poor diet, and excessive alcohol consumption. Some researchers suggest that negative consummatory behaviors play a direct causal role in CHD. The present study proposed that hostility predisposes an individual to these behaviors, and th… more

Date: August 1995

Creator: Buri, Robert J. (Robert John)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Isolation, Characterization and Physiological Studies of Cyanide-Utilizing Bacteria

Ten bacteria capable of growth on the metal-cyano complex, tetracyanonickelate (II) {K2 [Ni(CN)J } (TCN), supplied as the sole nitrogen source, were isolated. Seven isolates were identified as pseudomonads while the remaining three were classified as Klebsiella species. In addition to TCN, all isolates were able to utilize KCN although it was significantly more toxic. The degradation of TCN was most complete when supplied at growth-limiting concentrations, did not occur when ammonia was present… more

Date: December 1991

Creator: Silva Avalos, Juan G. (Juan Guillermo)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Factors Involved in the Selection of Medical Technology as a Major Field

The problem of this study concerned the factors involved in the selection of medical technology as a major. The purposes of the study were to determine (a) the most influential factors in the selection of medical technology as a career, (b) which sources of career information were the most frequently utilized and most influential in the choice of medical technology as a major, (c) the most common misperceptions of the field at the time of selection of the major, and (d) the relationship between… more

Date: December 1992

Creator: Jones, Gail A. (Gail Ann)

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

The Eosinophil Response in Mice Infected with Trichinella spiralis or Trichinella pseudospiralis as Indicated by Phospholipase B Activity

The host eosinophil response was compared in mice infected with either T. spiralis or T. pseudospiralis by determination of levels of splenic and intestinal phospholipase B, a marker enzyme for eosinophils. Primary infection of naive mice and challenge infection of homologously sensitized mice with T. pseudospiralis resulted in significantly lower tissue phospholipase B activities than infection with T. spiralis. Mice homologously challenged with T. pseudospiralis did exhibit an anamnestic eosi… more

Date: December 1992

Creator: Hsu, Shing-Chien

Item Type: Thesis or Dissertation

Partner: UNT Libraries

open access

Analysis of the Trypanosoma brucei Genome and Identification and Characterization of a Gene Family Encoding Putative EF-Hand Calcium-Binding Proteins

The flagellum of Trypanosoma brucei contains a family of antigenically related EF-hand calcium-binding proteins which are called the calflagins. Genomic Southern blots indicated that multiple copies of calflagin genes occur in T brucei. All of the copies were contained in a single 23 kb Xhol-Xhol fragment. Genomic fragments of 2.5 and 1.7 kb were cloned that encoded calflagin sequences. Two new members of the calflagin family were found from genomic clone sequences. The deduced amino acid seque… more

Date: May 1998

Creator: DeFord, James H. (James Henry), 1956-

Item Type: Thesis or Dissertation

Partner: UNT Libraries