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in subjects: "63 Radiation, Thermal, And Other Environmental Pollutant Effects On Living Organisms And Biological Materials"  
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Sterility Produced in Mice by Deuterium Oxide

Description: Sterility in C{sub 57} and Swiss mice has been produced by substituting D{sub 2}O for a part of the drinking water. The effective range lies between 5% and 30% D{sub 2}O. It appears that the effect is greater in C{sub 57} males than females and that the size and viability of the litter is affected.
Date: December 6, 1957
Creator: Hughes, Ann M. & Calvin, Melvin
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Bioavailability Of Organic Solvents In Soils: Input Into Biologically Based Dose-Response Models for Human Risk Assessments

Description: The purpose of this study is to determine the bioavailability of organic solvents following dermal exposures to contaminated soil and water. Breath analysis is being used to obtain real-time measurements of volatile organics in expired air following exposure in rats and humans. Rhesus monkeys were used as surrogates for humans in benzene exposures. The exhaled breath data was analyzed using physiologically based pharmacokinetic (PBPK) models to determine the dermal bioavailability of organic so… more
Date: December 31, 2000
Creator: Wester, Ronald C.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Genetic Analysis of Stress Responses in Soil Bacteria for Enhanced Bioremediation of Mixed Contaminants

Description: In order to realize the full potential of bioremediation, an understanding of microbial community and individual bacterial responses to the stresses encountered at contaminated sites is needed. Knowledge about genetic responses of soil and subsurface bacteria to environmental stresses, which include low nutrients, low oxygen, and mixed pollutants, will allow extrapolation of basic principles to field applications, either using indigenous bacteria or genetically engineered microorganisms. Defini… more
Date: December 31, 2000
Creator: Wong, Kwong-Kwok
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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RADIATION EFFECTS IN NUCLEAR WASTE MATERIALS

Description: The objective of this research was to develop fundamental understanding and predictive models of radiation effects in glasses and ceramics at the atomic, microscopic, and macroscopic levels, as well as an understanding of the effects of these radiation-induced solid-state changes on dissolution kinetics (i.e., radionuclide release). The research performed during the duration of this project has addressed many of the scientific issues identified in the reports of two DOE panels [1,2], particular… more
Date: December 31, 2000
Creator: Weber, William J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Plant Rhizosphere Effects on Metal Mobilization and Transport

Description: The myriad of human activities including strategic and energy development at various DOE installations have resulted in the contamination of soils and waterways that can seriously threaten human and ecosystem health. Development of efficacious and economical remediation technologies is needed to ameliorate these immensely costly problems. Bioremediation (both plant and microbe-based) has promising potential to meet this demand but still requires advances in fundamental knowledge. For bioremedia… more
Date: December 31, 2000
Creator: Fan, Teresa W.-M; Higashi, Richard M. & Crowley, David E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

DETERMINING SIGNIFICANT ENDPOINTS FOR ECOLOGICAL RISK ANALYS ES

Description: Our interest is in obtaining a scientifically defensible endpoint for measuring ecological risks to populations exposed to chronic, low-level radiation, and radiation with concomitant exposure to chemicals. To do so, we believe that we must understand the extent to which molecular damage is detrimental at the individual and population levels of biological organization. Ecological risk analyses based on molecular damage, without an understanding of the impacts to higher levels of biological orga… more
Date: December 31, 2000
Creator: Hinton, Thomas G.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Synchrotron infrared spectromicroscopy as a novel bioanalytical microprobe for individual living cells: Cytotoxicity considerations

Description: Synchrotron radiation-based Fourier transform infrared (SR-FTIR) spectromicroscopy is a newly emerging analytical tool capable of monitoring the biochemistry within an individual living mammalian cell in real time. This unique technique provides infrared (IR)spectra, hence chemical information, with high signal-to-noise at spatial resolutions as fine as 3 to 10 microns. Mid-IR photons are too low in energy (0.05-0.5 eV) to either break bonds or to cause ionization, and the synchrotron IR beam h… more
Date: December 12, 2001
Creator: Holman, Hoi-Ying N.; Bjornstad, Kathleen A.; McNamara, Morgan P.; Martin, Michael C.; McKinney, Wayne R. & Blakely, Eleanor A.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

MECHANISMS INVOLVED IN TRICHLOROETHYLENE INDUCED LIVER CANCER: IMPORTANCE TO ENVIRONMENTAL CLEANUP

Description: Trichloroethylene (TCE) is a common contaminant of groundwater as a result of poor disposal practices of the past. As a consequence, this solvent is the focus of many clean-up operations of uncontrolled hazardous waste sites. TCE is carcinogenic in both mice and rats, but at different sites, the liver and kidney, respectively (NCI 1976; NTP 1988; NTP 1990). Liver tumor induction in mice has been the tumor most critical from the standpoint of environmental regulation (Bull 2000). Under the propo… more
Date: December 31, 2001
Creator: Bull, Richard J. & Thrall, Brain D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Long-Term Risk From Actinides In The Environment: Modes Of Mobility

Description: The mobility of actinides in surface soils remains a key issue of concern at several DOE facilities in arid and semiarid environments, including Rocky Flats, Hanford, Nevada, Idaho, and Los Alamos. Over the last 50 years, nuclear research and development programs have resulted in releases of plutonium to both on-site and off-site locations. Most of this plutonium and other actinides are currently in soils where it is tightly bound to soil particles (Watters et al. 1983), but these particles the… more
Date: December 31, 2000
Creator: Breshears, David D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

The Effect of Habitat Inhomogeneities and Fragmentation on Population Density and Time to Extinction

Description: We present a study, based on simulations with SERDYCA, a spatially-explicit individual based model of rodent dynamics, on the connection between population persistence and the presence of inhomogeneities in the habitat. We are specifically interested on the effect that inhomogeneities that do not fragment the environment, have on population persistence. Our results suggest that a certain percentage of inhomogeneities can increase the average time to extinction of the population. Inhomogeneities… more
Date: December 22, 2003
Creator: Kostova, Tanya & Carlsen, Tina
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Plutonium Decontamination of Uranium using CO2 Cleaning

Description: A concern of the Department of Energy (DOE) Environmental Management (EM) and Defense Programs (DP), and of the Los Alamos National Laboratory (LANL) and the Lawrence Livermore National Laboratory (LLNL), is the disposition of thousands of legacy and recently generated plutonium (Pu)-contaminated, highly enriched uranium (HEU) parts. These parts take up needed vault space. This presents a serious problem for LLNL, as site limit could result in the stoppage of future weapons work. The Office of … more
Date: December 1, 2002
Creator: Blau, M
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Technical Basis for Also Using Health-Risk Assessment to Establish Contaminant Boundaries for Corrective Action Units (CAUs) of the Underground Test Area (UGTA) at the Nevada Test Site (NTS)

Description: This technical basis document serves two purposes. First, it provides a detailed discussion of the rationale and procedures suitable for deriving a risk-based contaminant boundary that will protect public health unambiguously, along with examples that are intended as illustrative only to facilitate understanding. Second, it explains the benefits of using such information as the framework for fostering risk communication to educate, inform, and enlighten, and importantly, to fully disclose the g… more
Date: December 29, 2003
Creator: Daniels, J I & Tompson, A F
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Mitigation Monitoring Program at Lawrence Livermore National Laboratory FY00 Annual Report

Description: Lawrence Livermore National Laboratory (LLNL) has completed eight years of implementing the mitigation measures from the Final Environmental Impact Statement/Environmental Impact Report (EIS/EIR) for the Continued Operation of LLNL and Sandia National Laboratories (SNL), Livermore. This eighth annual report documents LLNL's implementation of the mitigation measures during the fiscal year ending September 30, 2000 (FY00). It provides background information on the mitigation measures, describes a… more
Date: December 1, 2003
Creator: Mcguff, R R
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Monitoring Genetic and Metabolic Potential for in situ Bioremediation: Mass Spectrometry

Description: A number of DOE sites are contaminated with mixtures of dense non-aqueous phase liquids (DNAPLs) such as carbon tetrachloride, chloroform, perchloroethylene, and trichloroethylene. At many of these sites, in situ microbial bioremediation is an attractive strategy for cleanup, since it has the potential to degrade DNAPLs in situ without the need for pump-and-treat or soil removal procedures, and without producing toxic byproducts. A rapid screening method to determine broad range metabolic and g… more
Date: December 31, 2000
Creator: Buchanan, Michelle V.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

IMPROVED RISK ESTIMATES FOR CARBON TETRACHLORIDE

Description: Carbon tetrachloride has been used extensively within the DOE nuclear weapons facilities. Rocky Flats was formerly the largest volume consumer of CCl4 in the United States using 5000 gallons in 1977 alone (Ripple, 1992). At the Hanford site, several hundred thousand gallons of CCl4 were discharged between 1955 and 1973 into underground cribs for storage. Levels of CCl4 in groundwater at highly contaminated sites at the Hanford facility have exceeded 8 the drinking water standard of 5 ppb by sev… more
Date: December 31, 1999
Creator: Benson, Janet M. & Springer, David L.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Comparison of organochlorine chemical body burdens of female breast cancer cases with cancer free women in Rio Grande do Sul, Brazil--Pilot Study

Description: This pilot study collected preliminary data to examine known and suspected breast cancer risk factors among women living in rural and urban areas in the state of Rio Grande do Sul, Brazil by questionnaire. In addition, the body burden levels of a panel of organochlorines was measured in a small clinic-based prospective sample.
Date: December 1999
Creator: Erdmann, C. A.; Petreas, M. X.; Caleffi, M.; Barbosa, F. S. & Goth-Goldstein, R.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Enumeration of Microbial Populations in Radioactive Environments by Epifluorescence Microscopy

Description: Epifluorescence microscopy was utilized to enumerate halophilic bacterial populations in two studies involving inoculated, actual radioactive waste/brine mixtures and pure brine solutions. The studies include an initial set of experiments designed to elucidate potential transformations of actinide-containing wastes under salt-repository conditions, including microbially mediated changes. The first study included periodic enumeration of bacterial populations of a mixed inoculum initially added t… more
Date: December 2, 1996
Creator: Pansoy-Hjelvik, M. E. A.; Strietelmeierr, B. A.; Paffett, M. T.; Kitten, S. M.; Leonard, P. A.; Dunn, M. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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[Completion of the dog toxicity project at the University of Utah: statistical comparison]

Description: Radium (Ra) toxicity in dogs is a cornerstone for the evaluation of plutonium (Pu) toxicity, as it provides a possible link to Pu toxicity in humans. Survival regression models with covariates were used to estimate the risk to survival and the frequency and latency of bone tumor development. It appears for Ra that dose-rate is a more significant contributor to non-survival and bone tumors than is skeletal dose.
Date: December 15, 1999
Creator: Bruenger, F. W. & Lloyd, R. D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Idaho National Engineering and Environmental Laboratory Offsite Environmental Surveillance Program Report: Second Quarter 1999

Description: The Environmental Science and Research Foundation conducts an Offsite Environmental Surveillance Program at the US Department of Energy's Idaho National Engineering and Environmental Laboratory (INEEL). The Foundation's environmental surveillance program monitors the effects, if any, of US Department of Energy (DOE) activities on the offsite environment, collects data to confirm compliance with applicable environmental laws and regulations, and observes any trends in the environmental levels of… more
Date: December 1, 1999
Creator: Evans, R.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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