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open access

Bioengineering Systems for Modulating Notch Signaling in Cardiovascular Development, Disease, and Regeneration

Description: This article is a review summarizing the significant roles of Notch signaling in individual cardiac cell types. It covers the bioengineering systems of microfluidics, hydrogel, spheroid, and 3D bioprinting and provides insights into ancillary supports of bioengineering systems, varied types of cardiovascular cells, and advanced characterization approaches in further refining Notch signaling in cardiovascular development, disease, and regeneration.
Date: September 30, 2021
Creator: Huerta Gomez, Angello; Joshi, Sanika; Yang, Yong; Tune, Johnathan D. & Zhao, Ming-Tao
Partner: University of North Texas
open access

In-vitro biomineralization and biocompatibility of friction stir additively manufactured AZ31B magnesium alloy-hydroxyapatite composites

Description: Article presents research where friction stir additive manufacturing technique was employed to fabricate AZ31B magnesium-hydroxyapatite composite. The study aims to evaluate effect of hydroxyapatite (HA, Ca₁₀(PO₄)₆OH₂), a ceramic similar to natural bone, into AZ31B Mg alloy matrix on biomineralization and biocompatibility.
Date: June 30, 2020
Creator: Ho, Yee-Hsien; Man, Kun; Joshi, Sameehan; Pantawane, Mangesh V.; Wu, Tso-Chang; Yang, Yong et al.
Partner: UNT College of Engineering
open access

Optic-nerve-head (ONH) Chips for Glaucomatous Neurodegeneration

Description: Data management plan for the grant, "Optic-nerve-head (ONH) Chips for Glaucomatous Neurodegeneration." The most prominent causative risk factor of glaucoma, the leading cause of irreversible blindness worldwide, is elevated intraocular pressure (IOP), which could deform the optic nerve head (ONH) and cause glaucomatous neurodegeneration. However, current glaucoma therapies that focus on lowering IOP do not stop vision loss effectively, and thus there is a pressing need to understand the mechani… more
Date: 2022-09-30/2025-05-31
Creator: Yang, Yong
Partner: UNT College of Engineering
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