The purpose of this report is to document and detail the thermal releases from the Hanford nuclear production reactors during the period 1951 through 1971, and to put these releases in historical perspective with respect to changing Columbia River flows and temperatures. This information can also be used as a foundation for further ecological evaluations. When examining Hanford production reactor thermal releases to the Columbia River all related factors affecting the releases and the characteristics of the river should be considered. The major considerations in the present study were the characteristics of the releases themselves (primarily coolant flow rate, temperatures, discharge facilities, period of operation, and level of operation) and the characteristics of the river in that reach (primarily flow rate, temperature and mixing characteristics; the effects of dam construction were also taken into account). In addition, this study addressed ecological effects of thermal releases on aquatic species. Accordingly, this report includes discussion of the reactor cooling system, historical heat releases, thermal mixing and transport studies, hydroelectric power development, and ecologic effects of Hanford production reactor heat releases on salmon and trout. Appendix A contains reactor operating statistics, and Appendix B provide computations of heat added to the Columbia River between Priest Rapids Dam and Richland, Washington.