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Editorial

Description: The Tenth International Conference on Accelerator Mass Spectrometry (AMS-10) was held from September 5-10 at the University of California, Berkeley campus. The conference attracted 305 attendees from 26 countries who gave 144 platform presentations and presented a total of 170 posters. The conference opened with a special tribute to the late Roy Middleton, which was followed by a companion session on 'ion sourcery'. A plenary talk by Wally Broecker on his '53 years in the Radiocarbon Trenches',… more
Date: August 13, 2007
Creator: Knezovich, J; Brown, T; Buchholz, B; Finkel, B; Guilderson, T; Kashgarian, M et al.
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Partner: UNT Libraries Government Documents Department
open access

Single sample extraction and HPLC processing for quantification of NAD and NADH levels in Saccharomyces cerevisiae

Description: A robust redox extraction protocol for quantitative and reproducible metabolite isolation and recovery has been developed for simultaneous measurement of nicotinamide adenine dinucleotide (NAD) and its reduced form, NADH, from Saccharomyces cerevisiae. Following culture in liquid media, approximately 10{sup 8} yeast cells were harvested by centrifugation and then lysed under non-oxidizing conditions by bead blasting in ice-cold, nitrogen-saturated 50-mM ammonium acetate. To enable protein denat… more
Date: January 10, 2008
Creator: Sporty, J; Kabir, M M; Turteltaub, K; Ognibene, T; Lin, S & Bench, G
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Partner: UNT Libraries Government Documents Department
open access

Optimization of Direct Ionization of CO2 by Controlling the Gas Flow Inside of a Beam-Target

Description: We designed and optimized a target that directs a CO{sub 2} pulse onto a Ti surface where a Cs{sup +} sputtering beam ionizes the CO{sub 2} to generate C{sup -}. These targets will be used for the direct ionization of CO{sub 2} pulses to enable the measurement of carbon isotope ratios in real time. The design was based on the results of Comsol{trademark} simulations of the target configurations.
Date: March 7, 2011
Creator: Salazar Quintero, G A & Ognibene, T
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Partner: UNT Libraries Government Documents Department
open access

Analytical Validation of Accelerator Mass Spectrometry for Pharmaceutical Development: the Measurement of Carbon-14 Isotope Ratio.

Description: Accelerator mass spectrometry (AMS) is an isotope based measurement technology that utilizes carbon-14 labeled compounds in the pharmaceutical development process to measure compounds at very low concentrations, empowers microdosing as an investigational tool, and extends the utility of {sup 14}C labeled compounds to dramatically lower levels. It is a form of isotope ratio mass spectrometry that can provide either measurements of total compound equivalents or, when coupled to separation technol… more
Date: February 5, 2010
Creator: Keck, B D; Ognibene, T & Vogel, J S
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Partner: UNT Libraries Government Documents Department
open access

Counting Statistics and Ion Interval Density in AMS

Description: Confidence in the precisions of AMS and decay measurements must be comparable for the application of the {sup 14}C calibration to age determinations using both technologies. We confirmed the random nature of the temporal distribution of {sup 14}C ions in an AMS spectrometer for a number of sample counting rates and properties of the sputtering process. The temporal distribution of ion counts was also measured to confirm the applicability of traditional counting statistics.
Date: August 3, 2004
Creator: Vogel, J S; Ognibene, T; Palmblad, M & Reimer, P
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Partner: UNT Libraries Government Documents Department
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