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in creator/contributor: "Basu, Alakananda"  
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NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner

Description: This article's study endeavors to determine if p53 is responsible for cisplatin sensitization by NSC109268. Results have implications for sensitivity of ovarian cancer cells to cisplatin independent of p53.
Date: October 5, 2010
Creator: Shankar, Eswar; Basu, Chandreyi; Adkins, Brett; Siede, Wolfram & Basu, Alakananda
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Partner: UNT Health Science Center
open access

Regulation of Autophagy by Kinases

Description: This review focuses on the regulation of autophagy by several kinases with particular emphasis on serine/threonine protein kinases such as mTOR, AMP-activated kinase, Akt, mitogen-activated protein kinase (ERK, p38 and JNK) and protein kinase C that are often deregulated in cancer and are important therapeutic targets.
Date: June 9, 2011
Creator: Sridharan, Savitha; Jain, Kirti & Basu, Alakananda
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Partner: UNT Health Science Center
open access

The Enigmatic Protein Kinase C-eta

Description: The purpose of this review article is to discuss how PKCη regulates various cellular processes that may contribute to its contrasting roles in cancer. Protein kinase C-eta (PKCη) is a unique member of the PKC family since its regulation is distinct from other PKC isozymes. PKCη was shown to regulate cell proliferation, differentiation and cell death.
Date: February 13, 2019
Creator: Basu, Alakananda
Item Type: Refine your search to only Article
Partner: UNT Health Science Center
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