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Radiopharmaceuticals for diagnosis and treatment

Description: We report on our efforts in PET basic radiochemistry, radiopharmaceutical synthesis, and preclinical radiopharmaceutical evaluation. These efforts are focused on three fronts. First predictive abilities in nucleophilic aromatic substitution with [[sup 18]F]fluorination of substituted aromatic rings. Although radiochemical yields can be predicted within a very similar group of compounds with similar leaving groups and substituent patterns, generalization to all nucleophilic substitutions with [[… more
Date: January 1, 1992
Creator: Kuhl, D.E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Radiopharmaceuticals for diagnosis and treatment. Progress report

Description: We report on our efforts in PET basic radiochemistry, radiopharmaceutical synthesis, and preclinical radiopharmaceutical evaluation. These efforts are focused on three fronts. First predictive abilities in nucleophilic aromatic substitution with [{sup 18}F]fluorination of substituted aromatic rings. Although radiochemical yields can be predicted within a very similar group of compounds with similar leaving groups and substituent patterns, generalization to all nucleophilic substitutions with [{… more
Date: December 1, 1992
Creator: Kuhl, D. E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Chiral separation of pharmaceutical compounds using electrochemically modulated liquid chromatography (EMLC)

Description: This research explores the application of a new technique, termed electrochemically modulated liquid chromatography (EMLC), to the chiral separations of pharmaceutical compounds. The introduction section provides a literature review of the technique and its applications, as well as brief overview of the research described in each of the next two chapters. Chapter 2 investigates the EMLC-based enantiomeric separation of a group of chiral benzodiazepines with {beta}-cyclodextrin as a chiral mobil… more
Date: February 12, 1999
Creator: Wang, S.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries Government Documents Department
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