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Radiological and Environmental Research Division, Center for Human Radiobiology. Annual report, July 1980-June 1981. [Lead abstract]

Description: Separate abstracts were prepared for the 22 papers of this annual report of the Center for Human Radiobiology. Abstracts were not written for 2 appendices which contain data on the exposure and radium-induced malignancies of 2259 persons whose radium content has been determined at least once. (KRM)
Date: March 1, 1982
Partner: UNT Libraries Government Documents Department
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Evaluation of the mouse micronucleus test as compared with the in vivo cytogenics test for mutagenicity of synthetic fuel materials. Topical report

Description: This brief topical report, provides information on a comparison of the mouse micronucleus mutagenic test proposed by a DOE contractor (FMC) for coal derived chemicals; as compared with the in vivo cytogenic test. The latter procedure is repotedly preferred by EPA authorities connected with implementation of the toxic substances control act (TOSCA). This evaluation was performed at the request of Headquarters DOE program management staff. The mouse micronucleus test takes less time and costs app… more
Date: March 9, 1980
Partner: UNT Libraries Government Documents Department
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Studies in Development Immunogenetics. Annual Progress Report

Description: This contract provides the research support for a group concerned with a relatively large range of problems. The integrating thread that runs through it is that of an interest in development and its genetic regulation, mainly in complex organisms and with an emphasis on the immune system as a model for developmental analysis and as a tool for following the development of other systems, especially the brain. It includes studies of biochemical genetics, primarily from a developmental viewpoint an… more
Date: March 26, 1975
Creator: Owen, R. D.
Partner: UNT Libraries Government Documents Department
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Early and continuing effects of combined alpha and beta irradiation of the lung:

Description: This report summarizes an inhalation exposure experiment that concerns early and continuing effects of combined alpha and beta irradiation of the lung of rats. Both morbidity at 18 months and mortality within 18 months after exposure were examined for rats exposed to the beta-emitter /sup 147/Pm, the alpha-emitter /sup 238/Pu, or both combined. The results were used to validate hazard-function models that were developed (1)for pulmonary functional morbidity at 18 months and (2) for lethality fr… more
Date: March 1, 1988
Creator: Scott, B. R.; Hahn, F. F.; Snipes, M. B.; Newton, G. J.; Eidson, A. F.; Mauderly, J. L. et al.
Partner: UNT Libraries Government Documents Department
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Habitat associations of vertebrate prey within the controlled area study zone

Description: Twelve study locations were established in nine habitat types in the vicinity of the proposed reference repository location. Eight species of small mammals were captured. Great Basin pocket mice (Perognathus parvus) comprised the majority of individuals captured, followed by deer mice (Peromyscus maniculatus), Northern pocket gopher (Thomomys talpoides), Western harvest mouse (Reithrodontomys megalotus), Grasshopper mouse (Onychomys leucogaster), Montane vole, (Microtus montanus), House mouse (… more
Date: March 1, 1988
Creator: Marr, N. V.; Brandt, C. A.; Fitzner, R. E. & Poole, L. D.
Partner: UNT Libraries Government Documents Department
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Health aspects of power transmission. [Effects of 60 Hz electric field on biochemical, morphological, and physiological parameters in mice and rats]

Description: Exposure of rats and mice to 60-Hz electric fields at 100 kV/m for up to 120 days had no statistically significant, reproducible effects on a number of measures of metabolic status and growth, bone growth and structure, reproduction, hematology and serum chemistry, endocrinology, cardiovascular function, nerve function, or organ and tissue morphology. An effect on cell-mediated immunity was detected and is being evaluated further in additional experiments. Exposure of rats in utero (day 0 of ge… more
Date: March 1, 1979
Creator: Phillips, R. D.
Partner: UNT Libraries Government Documents Department
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Smokes and obscurants: A health and environmental effects data base assessment: A first-order, environmental screening and ranking of Army smokes and obscurants: Phase 1 report

Description: An initial environmental screening and ranking is provided for each Army smoke and obscurant (S and O) depending on smoke type and smoke-generating device. This was done according to the magnitude of the impact area, the characteristic environmental concentration, the relative inhalation toxicity, the relative toxicity when ingested by animals, the aquatic toxicity, the environmental mobility when freshly deposited, and the ultimate mobility and fate in the environment. The major smoke types co… more
Date: March 1, 1985
Creator: Shinn, J.H.; Martins, S.A.; Cederwall, P.L. & Gratt, L.B.
Partner: UNT Libraries Government Documents Department
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Reconfigured, close-coupled reconfigured, and Wyodak coal integrated two-stage coal liquefaction process materials from the Wilsonville facility: Chemical and toxicological evaluation

Description: This document reports the results of the chemical analysis and toxicological testing of process materials sampled during the operation of the Advanced Coal Liquefaction Research and Development Facility (Wilsonville, AL) in the reconfigured, integrated (RITSL run No. 247), the close-coupled, reconfigured, integrated (CCRITSL run No. 249), and the Wyodak coal integrated (ITSL run No. 246) two-stage liquefaction operating modes. Chemical methods of analysis included proton nuclear magnetic resona… more
Date: March 1, 1987
Creator: Wright, C.W.
Partner: UNT Libraries Government Documents Department
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Analysis of small mammal populations inhabiting the environs of a low-level radioactive waste pond.

Description: This study was designed to determine the kinds of small mammals living adjacent to 216-U-10 Pond, the radiation exposures these mice received, and the level and type of radionuclides assimilated while living next to this pond and the 216-Z-19 Ditch. Four species of mice were trapped including the Great Basin pocket mouse, deer mouse, house mouse, and the western harvest mouse. Animals were collected throughout the study and composite tissue samples were analyzed by gamma spectrometry. Also, an … more
Date: March 1, 1979
Creator: Gano, K.A.
Partner: UNT Libraries Government Documents Department
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Radioactivity Associated With Biota and Soils of the 216-A-24 Crib

Description: The 216-A-24 Crib was used from 1958 to 1966 to receive condensate (/sup 137/Cs, /sup 90/Sr) from the 241-A and 241-AX Tank Farms. In 1975, rabbitbrush plants (Chrysothamnus nauseosus) growing on the crib were found to contain radioactive materials. Highest levels of activity and densest stands of rabbitbrush plants were in the center of the second section of the crib where a Geiger--Mueller count rate meter showed surface exposure rates of certain plants to be as high as 125 times background. … more
Date: March 1979
Creator: Klepper, E. L.; Rogers, L. E.; Hedlund, J. D. & Schreckhise, R. G.
Partner: UNT Libraries Government Documents Department
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Toxicity of tritium. [Chronic, low-dose exposure of mice and monkeys]

Description: Among radionuclides of importance in atomic energy, /sup 3/H has relatively low toxicity. The main health and environmental worry is the possibility that significant biological effects may follow from protracted exposure to low concentrations in water. To examine this possible hazard and measure toxicity at low tritium concentrations, chronic exposure studies were done on mice and monkeys. During vulnerable developmental periods animals were exposed to /sup 3/HOH, and mice were exposed also to … more
Date: March 2, 1979
Creator: Dobson, R.L.
Partner: UNT Libraries Government Documents Department
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Research in radiobiology: Final report of work in progress in immunobiology of experimental host-tumor relationships

Description: Our work on the immunobiology of tumors induced in normal mice by non-ionizing radiation and chemical carcinogens has previously demonstrated a correlation between MHC molecule expression and the immunogenicity of tumors in a transplanted syngeneic host. Such that immunogenic or regressive tumors were found to demonstrate higher constitutive or inducible levels of MHC expression, while most virulent, aggressive tumors exhibited a low level of MHC Class I expression. We attributed much of the co… more
Date: March 15, 1993
Partner: UNT Libraries Government Documents Department
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Dosimetry, instrumentation and exposure chambers for dc magnetic field studies

Description: The principal objective of this report is to describe in detail an exposure chamber that was developed at the Lawrence Berkeley Laboratory for automated, noninvasive studies of rodent physiology during exposure to high DC magnetic fields. A second objective is to discuss some of the unique instrumentation problems that must be overcome in order to record bioelectric signals from laboratory animals in the presence of a magnetic field. Finally, a description will be given of the various dosimetry… more
Date: March 1, 1979
Creator: Tenforde, T. S.
Partner: UNT Libraries Government Documents Department
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Biological/environmental relationships in desert ecosystems of the Nevada Test Site

Description: Activities covered are: computer and related work (corrections and updating of card decks for Nevada Test Site data, and transfer of data and programs to tapes); publication of shrub (and tree) data for undisturbed Test Site vegetation in 1963 and 1975 (DOE/EV/2307-15); work performed in this contract period on the publications covering the vascular plants of central-southern Nevada (TID-26881); and work and publications in connection with the Endangered and Threatened species of central-southe… more
Date: March 1, 1979
Creator: Beatley, Janice C.
Partner: UNT Libraries Government Documents Department
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Nuclear medicine program progress report for quarter ending December 31, 1992

Description: We describe the synthesis of the cis- and trans-iodovinyl isomers of the new ORNL cholinergic-muscarinicreceptorligand, 1 -azabicyclo[2.2-2]oct-3-yl[alpha]-hydroxy-[alpha]-(1-iodo-l-propen-3-yl)-[alpha]-phenylacetate ( IQNP''). This agent is prepared in high radiochemical yield, and the racemic mixture shows high specificity and selectivity for the cerebral and myocardial receptors. Since two chiral centers are present in this molecule, it is important to evaluate the importance of the absolute… more
Date: March 1, 1993
Creator: Knapp, F. F., Jr.; Ambrose, K. R.; Beets, A. L.; Callahan, A. P.; McPherson, D. W.; Mirzadeh, S. et al.
Partner: UNT Libraries Government Documents Department
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Analytical approaches to and interpretations of data on time, rate, and cause of death of mice exposed to external gamma irradiation

Description: Young adult male and female mice of inbred strains, A, BALB/c, C57BL/6, and C57L, and B6CF/sub 1/ and F/sub 2/ hybrids were exposed to daily duration-of-life external /sup 60/Co ..gamma.. irradiation. Age at death was recorded, and most decedents were necropsied to ascertain occurrence of major types of tumors. Age- and cause-specific mortality or incidence rates were derived, and their regressions on age were fitted with polynomial equations by least-squares procedures. Age-specific and age-ad… more
Date: March 13, 1978
Creator: Grahn, D.; Sacher, G.A.; Lea, R.A.; Fry, R.J.M. & Rust, J.H.
Partner: UNT Libraries Government Documents Department
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Cataract production in mice by heavy charged particles

Description: The cataractogenic effects of heavy charged particles have been evaluated in mice in relation to dose and ionization density (LET/sub infinity/). The study was undertaken due to the high potential for eye exposures to HZE particles among SPS personnel working in outer space. This has made it imperative that the relative biological effectiveness (RBE) in relation to LET/sub infinity/ for various particles be defined so that appropriate quality factors (Q) could be assigned for estimation of risk… more
Date: March 1, 1981
Creator: Ainsworth, E.H.; Jose, J.; Yang, V.V. & Barker, M.E.
Partner: UNT Libraries Government Documents Department
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Radiation Carcinogenesis. Comprehensive Three-year Progress Report, 1 May 1972--15 March 1976.

Description: Progress is reported on studies on the pathological effects of various doses of x radiation on rats and mice, with emphasis on radioinduced carcinogenesis in parabiont rats with one of the pair exposed to 1000 R of whole body x radiation and the other shielded. Results are included from studies on alterations in metabolic parameters and life span induced by irradiation. (CH)
Date: March 1, 1976
Creator: Warren, Shields & Gates, Olive
Partner: UNT Libraries Government Documents Department
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Radiation Carcinogenesis. Progress Report III, 15 March 1975--15 March 1976.

Description: The attention of forensic pathologists has been drawn to the criteria essential for the recognition of radiation death or injury in the hope that such cases will be better recognized and that some false claims of radiation damage might be prevented at the local level. The results of experiments on parabiont rats, one of which had been irradiated with 1000 R of 250 kVp x-ray, the other shielded, are reviewed. With controls and related special studies the total is over 3000 pairs equally divided … more
Date: March 1, 1976
Creator: Warren, Shields & Gates, Olive
Partner: UNT Libraries Government Documents Department
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Radiation Carcinogenesis. Comprehensive Final Report, 16 May 1979-31 December 1980

Description: This abstract covers three main areas of investigation: mesothelioma induction by asbestos, radiation tumorigenesis and transplantable tumors. Canadian and Rhodesian asbestos fibers have been administered under anesthesia to rats by intratracheal, intrapleural and intraperitoneal injection. Additional groups were given 3-methylcholanthrene or x-radiation along with asbestos. A large series of mice also treated as above have displayed mesotheliomas. In addition, glass fiber injections and feedin… more
Date: March 1, 1981
Creator: Warren, Shields; Brown, Clark E. & Gates, Olive
Partner: UNT Libraries Government Documents Department
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Hantavirus testing in rodents of north-central New Mexico 1993-1995

Description: In 1993, an outbreak of a new strain of hantavirus in the southwestern US indicated that deer mice (Peromyscus maniculatus) was the primary carrier of the virus. In 1993, 1994, and 1995 the Ecological Studies Team (EST) at Los Alamos National Laboratory surveyed small mammal populations using live capture-recapture methods in Los Alamos County, New Mexico, to determine seroprevalence of hantavirus in this region. EST used trapping grids in 1993 and 1994 and used trapping webs in 1995. Grids wer… more
Date: March 1, 1996
Creator: Biggs, J.; Bennett, K. & Salisbury, M.
Partner: UNT Libraries Government Documents Department
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Mid-Pacific Marine Laboratory. Annual report for the period, 1 October 1977--30 September 1978

Description: Studies on behavior included reproduction and sociobiology of reef fishes and aggression, hearing, and ultrasonic telemetry in sharks. Ecological studies included population, growth, and mortality studies on birds, corals, crustacea, echinoderms, fishes, molluscs, and rats. Geochemistry studies included biogeochemistry of reef organisms and hydrogeochemistry of groundwater. Geology studies included bioerosion of sea urchins, biology of endolithic processes, and survey of soils. Oceanography stu… more
Date: March 1, 1979
Creator: Reese, Ernst S. & Johnson, Victor R., Jr.
Partner: UNT Libraries Government Documents Department
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