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Final Technical Report

Description: The best summary of our results is probably provided by the list of publications based on work supported by this grant, which is given below. In general, the objectives were realized, and we have demonstrated, for the first time, that radiolabeled Abs can kill single tumor cells very effectively, and that they can also be effective in treating models of human tumors growing as xenografts in SCID mice. Our original work, as proposed in the application, was with Abs to B-lymphoma cells, namely an… more
Date: June 10, 2005
Creator: Mattes, M. Jules
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Clostridium Spore Attachment to Human Cells

Description: This paper uses high resolution scanning electron microscopy (SEM) with a LaB6 gun and the newest commercial field emission guns, to obtain high magnification images of intact clostridial spores throughout the activation/germination/outgrowth process. By high resolution SEM, the clostridial exosporial membrane can be seen to produce numerous delicate projections (following activation), that extend from the exosporial surface to a nutritive substrate (agar), or cell surface when anaerobically in… more
Date: August 10, 1997
Creator: Panessa-Warren, B.; Tortora, G. & Warren, J.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Solar Radiation and Induction of DNA Damage, Mutations and Skin Cancers.

Description: An understanding of the effects of sunlight on human skin begins with the effects on DNA and extends to cells, animals and humans. The major DNA photoproducts arising from UVB (280-320 nm) exposures are cyclobutane pyrimidine dimers. If unrepaired, they may kill or mutate cells and result in basal and squamous cell carcinomas. Although UVA (320-400 nm) and visible wavelengths are poorly absorbed by DNA, the existing data indicate clearly that exposures to these wavelengths are responsible, in a… more
Date: May 10, 2007
Creator: Setlow, Richard. B.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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