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open access

Flow cytometric analysis of mitotic cycle perturbation by chemical carcinogens in cultured epithelial cells. [Effects of benzo(a)pyrene-diol-epoxide on mitotic cycle of cultural mouse liver epithelial cells]

Description: A system for kinetic analysis of mitotic cycle perturbation by various agents was developed and applied to the study of the mitotic cycle effects and dependency of the chemical carcinogen benzo(a)pyrene-diolepoxide, DE, upon a mouse lever epithelial cell line, NMuLi. The study suggests that the targets of DE action are not confined to DNA alone but may include cytoplasmic structures as well. DE was found to affect cells located in virtually every phase of the mitotic cycle, with cells that were… more
Date: August 1, 1978
Creator: Pearlman, A.L.
Partner: UNT Libraries Government Documents Department
open access

Magnetic Tools for Lab-on-a-chip Technologies

Description: This study establishes a set of magnetics-based tools that have been integrated with microfluidic systems. The overall impact of the work begins to enable the rapid and efficient manipulation and detection of magnetic entities such as particles, picoliter-sized droplets, or bacterial cells. Details of design, fabrication, and theoretical and experimental assessments are presented. The manipulation strategy has been demonstrated in the format of a particle diverter, whereby micron-sized particle… more
Date: August 5, 2006
Creator: Pekas, Nikola Slobodan
Partner: UNT Libraries Government Documents Department
open access

Optimization of the Mini-Flo flow cytometer

Description: A new method of collecting light scattering from a liquid flow cytometer has been proposed; this apparatus is named the Mini-Flo flow cytometer. The Mini-Flo uses a high numerical aperture collection immersed in the flow stream. The collector consists of a conically tipped fiber optic pipe and terminating optical detector. This study was performed to improve the signal/noise ration and optimize the Mini-Flo`s performance for HIV blood detection applications. Experiments were performed to gauge … more
Date: June 1, 1996
Creator: Venkatesh, M.
Partner: UNT Libraries Government Documents Department
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