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open access

The complexities of proanthocyanidin biosynthesis and its regulation in plants

Description: Article describes how proanthocyanidins (PAs) are natural flavan-3-ol polymers that contribute protection to plants under biotic and abiotic stress, benefits to human health, and bitterness and astringency to food products. This review extends the conventional understanding with recent findings that provide new insights to address lingering questions and focus strategies for manipulating PA traits in plants.
Date: November 26, 2022
Creator: Yu, Keji; Song, Yushuang; Lin, Jinxing & Dixon, R. A.
open access

Growth of Highly-Ordered Metal Nanoparticle Arrays in the Dimpled Pores of an Anodic Aluminum Oxide Template

Description: Article presents a reliable, scalable, and inexpensive technology for the fabrication of ordered arrays of metal nanoparticles with large areal coverage on various substrates. Using a simple model, the experimental results were interpreted and supported by numerical estimations.
Date: November 8, 2022
Creator: Farmer, Gavin; Abraham, James; Littler, Chris; Syllaios, A. J. & Philipose, Usha
open access

Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm

Description: Article discusses how lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a phospholipid monolayer. The authors review the growing body of knowledge about lipid droplets in plant cells, describe the evolutionary similarity and divergence in their associated subcellular machinery, and point to gaps that deserve future attention.
Date: November 22, 2022
Creator: Guzha, Athanas; Whitehead, Payton; Ischebeck, Till & Chapman, Kent Dean
open access

A lipidomics platform to analyze the fatty acid compositions of non-polar and polar lipid molecular species from plant tissues: Examples from developing seeds and seedlings of pennycress (Thlaspi arvense)

Description: Article describes a stepwise targeted lipidomics approach to characterize the polar and non-polar lipid classes using complementary LC-MS methods. This lipidomics workflow was applied to developing, mature, and germinated pennycress seeds/seedlings and found unexpected changes among several lipid molecular species.
Date: November 9, 2022
Creator: Romsdahl, Trevor B.; Cocuron, Jean-Christophe; Pearson, Mackenzie J.; Alonso, Ana Paula & Chapman, Kent Dean
open access

Long-range current-induced spin accumulation in chiral crystals

Description: Article states that chiral materials, similarly to human hands, have distinguishable right-handed and left-handed enantiomers which may behave differently in response to external stimuli, so for the first time the authors use an approach based on the density functional theory (DFT)+PAOFLOW calculations to quantitatively estimate the so-called collinear Rashba–Edelstein effect (REE) that generates spin accumulation parallel to charge current and can manifest as chirality-dependent charge-to-spin… more
Date: November 18, 2022
Creator: Roy, Arunesh; Cerasoli, Frank T.; Jayaraj, Anooja; Tenzin, Karma; Buongiorno Nardelli, Marco & Sławińska, Jagoda
open access

Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds

Description: Authors of the article propose that thyroid hormones play an important role in regulating development of endothermy during the nestling period in altricial birds. Their data suggests plasma thyroid hormone levels play an active role in the systemic development of endothermic capacity and the development of ventilatory control.
Date: November 29, 2022
Creator: Sirsat, Tushar S.; Sirsat, Sarah K. G.; Price, Edwan R.; Pineda, Megan & Dzialowski, Edward M. (Edward Michael)
open access

Prebiotic/probiotic supplementation resulted in reduced visceral fat and mRNA expression associated with adipose tissue inflammation, systemic inflammation, and chronic disease risk

Description: Article describes how prebiotic/probiotic supplementation represents a viable option for addressing elevated systemic inflammation and chronic disease risk in overweight individuals. The key findings support that 90-day prebiotic/probiotic supplementation may be associated with reduced adipose tissue inflammation, reduced systemic inflammation, and reduced chronic disease risk.
Date: November 28, 2022
Creator: McFarlin, Brian K.; Tanner, Elizabeth A.; Hill, David W. & Vingren, Jakob L.
open access

The protein conformational basis of isoflavone biosynthesis

Description: Authors of the article assert that isoflavonoids play important roles in plant defense and also exhibit a range of mammalian health-promoting activities. They emphasize that understanding the structural basis of isoflavone biosynthesis will facilitate the engineering of new bioactive isoflavonoids.
Date: November 15, 2022
Creator: Wang, Xiaoqiang; Pan, Haiyun; Sagurthi, Someswar; Paris, Vincent; Zhuo, Chunliu & Dixon, R. A.
open access

Reconstructing horizontal gene flow network to understand prokaryotic evolution

Description: Article says that horizontal gene transfer (HGT) is a major source of phenotypic innovation and a mechanism of niche adaptation in prokaryotes. Methods for detecting HGT can be classified into phylogenetic-based and parametric or composition-based approaches, so authors exploited the complementary strengths of both the approaches to construct a high confidence horizontal gene flow network. The scale-free horizontal gene flow network presented here provides new insights into modes of transfer fo… more
Date: November 30, 2022
Creator: Sungupta, Soham & Azad, Rajeev K.
open access

Reweighted Manifold Learning of Collective Variables from Enhanced Sampling Simulations

Description: Article provides a general reweighting framework based on anisotropic diffusion maps for manifold learning that takes into account that the learning data set is sampled from a biased probability distribution. The authors show that their proposed framework can be used in many manifold learning techniques on data from both standard and enhanced sampling simulations.
Date: November 11, 2022
Creator: Rydzewski, Jakub; Chen, Ming; Ghosh, Tushar K. & Valsson, Omar
open access

The Shadow Effect on Surface Biophysical Variables Derived from Remote Sensing: A Review

Description: Article states that the main objective of this study was to review the recent literature on the shadow effect in remote sensing. An overview of the proposed methods for identifying and removing the shadow effect is presented.
Date: November 12, 2022
Creator: Alavipanah, Seyed Kazem; Firozjaei, Mohammad Karimi; Sedighi, Amir; Fathololoumi, Solmaz; Naghadehi, Saeid Zare; Saleh, Samiraalsadat et al.
open access

Three Component Cascade Reaction of Cyclohexanones, Aryl Amines, and Benzoylmethylene Malonates: Cooperative Enamine-Brønsted Acid Approach to Tetrahydroindoles

Description: Article discusses how a three-component cascade reaction comprising cyclic ketones, arylamines, and benzoylmethylene malonates has been developed to access 4,5,6,7-tetrahydro-1H-indoles. Furthermore, the reaction was achieved through cooperative enamine-Brønsted catalysis in high yields with wide substrate scopes.
Date: November 30, 2022
Creator: Vasquez, Jose Cortes; Alharbi, Waad S.; Davis, Jacqkis; Moore, Alexia; Nesterov, Vladimir N.; Cundari, Thomas R., 1964- et al.
open access

Transcriptomic profiling of miR-203a inhibitor and miR-34b-injected zebrafish (Danio rerio) validates oil-induced neurological, cardiovascular and eye toxicity response pathways

Description: Article discusses how the global sequencing of microRNA (miRNA; miR) and integration to downstream mRNA expression profiles in early life stages (ELS) of fish following exposure to crude oil determined consistently dysregulated miRNAs regardless of the oil source or fish species. The overlay of differentially expressed miRNAs and mRNAs into in silico software determined that the key roles of these miRNAs were predicted to be involved in cardiovascular, neurological and visually-mediated pathway… more
Date: November 21, 2022
Creator: Maguson, Jason T.; Leads, Rachel R.; McGruer, Victoria; Qian, Le; Tanabe, Philip; Roberts, Aaron P. et al.
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