Comparison of the effects of inhaled {sup 239}PuO{sub 2} and {beta}- emitting radionuclides on the incidence of lung carcinomas in laboratory animals

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The health effects of inhaling radioactive particles when the lung is the primary organ irradiated were studied in rats and Beagle dogs. The animals were exposed to aerosols of {sup 239}PuO{sub 2} or fission-product radionuclides in insoluble forms and observed for their life span. Lung carcinomas were the primary late-occuring effect. The incidence rate for lung carcinomas was modeled using a proportional hazard rate model. Linear functions predominated below 5 Gy to the lung. The life-time risk for lung carcinomas per 10{sup 4} Gy for beta emitters was 60 for rats and 65 for dogs, and for {sup 239}PuO{sub 2} … continued below

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Medium: P; Size: 4 p.

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Hahn, F. F.; Griffith, W. C.; Boecker, B. B.; Muggenburg, B. A. & Lundgren, D. L. December 31, 1991.

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The health effects of inhaling radioactive particles when the lung is the primary organ irradiated were studied in rats and Beagle dogs. The animals were exposed to aerosols of {sup 239}PuO{sub 2} or fission-product radionuclides in insoluble forms and observed for their life span. Lung carcinomas were the primary late-occuring effect. The incidence rate for lung carcinomas was modeled using a proportional hazard rate model. Linear functions predominated below 5 Gy to the lung. The life-time risk for lung carcinomas per 10{sup 4} Gy for beta emitters was 60 for rats and 65 for dogs, and for {sup 239}PuO{sub 2} it was 1500 for rats and 2300 for dogs.

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Medium: P; Size: 4 p.

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OSTI; NTIS; INIS; GPO Dep.

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  • 8. International Radiation Protection Association (IRPA) world congress,Vancouver (Canada),10-22 May 1992

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  • Other: DE92004259
  • Report No.: CONF-920501--8
  • Grant Number: AC04-76EV01013
  • Office of Scientific & Technical Information Report Number: 10108100
  • Archival Resource Key: ark:/67531/metadc1271794

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  • December 31, 1991

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  • Oct. 12, 2018, 6:44 a.m.

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Thumbnail image of item number 1 in: 'Comparison of the effects of inhaled {sup 239}PuO{sub 2} and {beta}- emitting radionuclides on the incidence of lung carcinomas in laboratory animals'.
Thumbnail image of item number 2 in: 'Comparison of the effects of inhaled {sup 239}PuO{sub 2} and {beta}- emitting radionuclides on the incidence of lung carcinomas in laboratory animals'.
Thumbnail image of item number 3 in: 'Comparison of the effects of inhaled {sup 239}PuO{sub 2} and {beta}- emitting radionuclides on the incidence of lung carcinomas in laboratory animals'.
Thumbnail image of item number 4 in: 'Comparison of the effects of inhaled {sup 239}PuO{sub 2} and {beta}- emitting radionuclides on the incidence of lung carcinomas in laboratory animals'.

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Hahn, F. F.; Griffith, W. C.; Boecker, B. B.; Muggenburg, B. A. & Lundgren, D. L. Comparison of the effects of inhaled {sup 239}PuO{sub 2} and {beta}- emitting radionuclides on the incidence of lung carcinomas in laboratory animals, article, December 31, 1991; United States. (https://digital.library.unt.edu/ark:/67531/metadc1271794/: accessed July 16, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.

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