Radiolabeled red blood cells: status, problems, and prospects

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Radionuclidic labels for red cells can be divided into two main categories - cohort or pulse labels, and random labels. The random labels are incorporated into circulating cells of all ages and the labeling process is usually carried out in vitro. The red cell labels in predominant use involve random labeling and employ technetium-99m, chromium-51, indium-111, and gallium-68, roughly in that order. The extent of usefulness depends on the properties of the label such as the half-life, decay mode, and in-vivo stability, etc. Labeled cells can be used for red cell survival measurements when the half-life of the radionuclide is … continued below

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44 pages

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Srivastava, S.C. January 1, 1983.

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Description

Radionuclidic labels for red cells can be divided into two main categories - cohort or pulse labels, and random labels. The random labels are incorporated into circulating cells of all ages and the labeling process is usually carried out in vitro. The red cell labels in predominant use involve random labeling and employ technetium-99m, chromium-51, indium-111, and gallium-68, roughly in that order. The extent of usefulness depends on the properties of the label such as the half-life, decay mode, and in-vivo stability, etc. Labeled cells can be used for red cell survival measurements when the half-life of the radionuclide is sufficiently long. The major portion of this article deals with random labels.

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44 pages

Notes

NTIS, PC A03/MF A01; 1.

Source

  • NATO advanced study institute on radiolabeled cellular blood, Maratea, Italy, 29 Aug 1983

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  • Other: DE84006481
  • Report No.: BNL-34153
  • Report No.: CONF-8308156-1
  • Grant Number: AC02-76CH00016
  • Office of Scientific & Technical Information Report Number: 5269687
  • Archival Resource Key: ark:/67531/metadc1071650

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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  • January 1, 1983

Added to The UNT Digital Library

  • Feb. 4, 2018, 10:51 a.m.

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  • Feb. 10, 2021, 11:19 p.m.

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Srivastava, S.C. Radiolabeled red blood cells: status, problems, and prospects, article, January 1, 1983; Upton, New York. (https://digital.library.unt.edu/ark:/67531/metadc1071650/: accessed July 17, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.

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