Physiological imaging with PET and SPECT in Dementia
Description
Dementia is a medical problem of increasingly obvious importance. The most common cause of dementia, Alzheimer's disease (AD) accounts for at least 50% of all cases of dementia, with multi-infarct dementia the next most common cause of the syndrome. While the accuracy of diagnosis of AD may range from 80 to 90%, there is currently no laboratory test to confirm the diagnosis. Functional imaging techniques such as positron emission tomography (PET) and single photon emission computed tomography (SPECT) offer diagnostic advantages since brain function is unequivocally disturbed in all dementing illnesses. Both PET and SPECT have been utilized in the … continued below
Physical Description
19 pages
Creation Information
Jagust, W.J. (California Univ., San Francisco, CA (United States). Dept. of Neurology Lawrence Berkeley Lab., CA (United States)) October 1, 1989.
Context
This article is part of the collection entitled: Office of Scientific & Technical Information Technical Reports and was provided by the UNT Libraries Government Documents Department to the UNT Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 68 times. More information about this article can be viewed below.
Who
People and organizations associated with either the creation of this article or its content.
Sponsors
- United States. Department of Energy. DOE; USDOE, Washington, DC (United States)
- United States. Department of Health and Human Services. DOHHS; Department of Health and Human Services, Washington, DC (United States)
Publisher
-
Lawrence Berkeley Laboratory
Place of Publication: [Berkeley,] California
Provided By
UNT Libraries Government Documents Department
Serving as both a federal and a state depository library, the UNT Libraries Government Documents Department maintains millions of items in a variety of formats. The department is a member of the FDLP Content Partnerships Program and an Affiliated Archive of the National Archives.
Contact Us
What
Descriptive information to help identify this article. Follow the links below to find similar items on the Digital Library.
Description
Dementia is a medical problem of increasingly obvious importance. The most common cause of dementia, Alzheimer's disease (AD) accounts for at least 50% of all cases of dementia, with multi-infarct dementia the next most common cause of the syndrome. While the accuracy of diagnosis of AD may range from 80 to 90%, there is currently no laboratory test to confirm the diagnosis. Functional imaging techniques such as positron emission tomography (PET) and single photon emission computed tomography (SPECT) offer diagnostic advantages since brain function is unequivocally disturbed in all dementing illnesses. Both PET and SPECT have been utilized in the study of dementia. While both techniques rely on principles of emission tomography to produce three dimensional maps of injected radiotracers, the differences between positron and single photon emission have important consequences for the practical applications of the two procedures. This briefly reviews the technical differences between PET and SPECT, and discusses how both techniques have been used in our laboratory to elucidate the pathophysiology of dementia. 32 refs., 2 figs.
Physical Description
19 pages
Notes
OSTI; NTIS; INIS; GPO Dep.
Subjects
Keywords
- Adults
- Age Groups
- Aged Adults
- Antimetabolites
- Beta Decay Radioisotopes
- Beta-Minus Decay Radioisotopes
- Beta-Plus Decay Radioisotopes
- Blood Flow
- Body
- Brain
- Carbon 11
- Carbon Isotopes
- Central Nervous System
- Cerebrum
- Computerized Tomography
- Days Living Radioisotopes
- Diagnostic Techniques
- Diagnostic Uses
- Diseases
- Drugs
- Elderly People
- Electron Capture Radioisotopes
- Emission Computed Tomography
- Even-Odd Nuclei
- Fluorodeoxyglucose
- Hours Living Radioisotopes
- Human Populations
- Intermediate Mass Nuclei
- Internal Conversion Radioisotopes
- Iodine 123
- Iodine Isotopes
- Isomeric Transition Isotopes
- Isotope Applications
- Isotopes
- Labelled Compounds
- Light Nuclei
- Minority Groups
- Minutes Living Radioisotopes
- Nervous System
- Nervous System Diseases
- Nuclei
- Odd-Even Nuclei
- Organs
- Oxygen 15
- Oxygen Isotopes
- Pathology
- Populations
- Positron Computed Tomography
- Radioisotopes
- Radiopharmaceuticals
- Single Photon Emission Computed Tomography
- Technetium 99
- Technetium Isotopes
- Tomography
- Tracer Techniques
- Uses
- Xenon 133
- Xenon Isotopes
- Years Living Radioi 550601* -- Medicine-- Unsealed Radionuclides In Diagnostics
STI Subject Categories
Source
- Neuroimaging symposium of the world congress of neurology, New Delhi (India), 21-27 Oct 1989
Language
Item Type
Identifier
Unique identifying numbers for this article in the Digital Library or other systems.
- Other: DE91017098
- Report No.: LBL-27935
- Report No.: CONF-8910542--1
- Grant Number: AC03-76SF00098
- Office of Scientific & Technical Information Report Number: 5450667
- Archival Resource Key: ark:/67531/metadc1071389
Collections
This article is part of the following collection of related materials.
Office of Scientific & Technical Information Technical Reports
Reports, articles and other documents harvested from the Office of Scientific and Technical Information.
Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.
Digital Files
When
Dates and time periods associated with this article.
Creation Date
- October 1, 1989
Added to The UNT Digital Library
- Feb. 4, 2018, 10:51 a.m.
Description Last Updated
- Jan. 14, 2020, 4:29 p.m.
Usage Statistics
When was this article last used?
Interact With This Article
Here are some suggestions for what to do next.
Start Reading
Citations, Rights, Re-Use
International Image Interoperability Framework
We support the IIIF Presentation API
Print / Share
Links for Robots
Helpful links in machine-readable formats.
Archival Resource Key (ARK)
- ERC Record: /ark:/67531/metadc1071389/?
- Persistence Statement: /ark:/67531/metadc1071389/??
International Image Interoperability Framework (IIIF)
- IIIF Manifest: /ark:/67531/metadc1071389/manifest/
Metadata Formats
- UNTL Format: /ark:/67531/metadc1071389/metadata.untl.xml
- DC RDF: /ark:/67531/metadc1071389/metadata.dc.rdf
- DC XML: /ark:/67531/metadc1071389/metadata.dc.xml
- OAI_DC: /oai/?verb=GetRecord&metadataPrefix=oai_dc&identifier=info:ark/67531/metadc1071389
- METS: /ark:/67531/metadc1071389/metadata.mets.xml
- OpenSearch Document: /ark:/67531/metadc1071389/opensearch.xml
Images
- Thumbnail: /ark:/67531/metadc1071389/thumbnail/
- Small Image: /ark:/67531/metadc1071389/small/
URLs
- In-text: /ark:/67531/metadc1071389/urls.txt
Stats
- Usage Stats: /stats/stats.json?ark=ark:/67531/metadc1071389
Jagust, W.J. (California Univ., San Francisco, CA (United States). Dept. of Neurology Lawrence Berkeley Lab., CA (United States)). Physiological imaging with PET and SPECT in Dementia, article, October 1, 1989; [Berkeley,] California. (https://digital.library.unt.edu/ark:/67531/metadc1071389/: accessed July 17, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.