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in subjects: "Modular Structures"

open access

Analysis of the structure of complex networks at different resolution levels

Modular structure is ubiquitous in real-world complex networks, and its detection is important because it gives insights in the structure-functionality relationship. The standard approach is based on the optimization of a quality function, modularity, which is a relative quality measure for a partition of a network into modules. Recently some authors have pointed out that the optimization of modularity has a fundamental drawback: the existence of a resolution limit beyond which no modular struc… more

Date: February 28, 2008

Creator: Arenas, A.; Fernandez, A. & Gomez, S.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Evolutionary expansion and divergence in a large family of primate-specific zinc finger transcription factor genes

Although most genes are conserved as one-to-one orthologs in different mammalian orders, certain gene families have evolved to comprise different numbers and types of protein-coding genes through independent series of gene duplications, divergence and gene loss in each evolutionary lineage. One such family encodes KRAB-zinc finger (KRAB-ZNF) genes, which are likely to function as transcriptional repressors. One KRAB-ZNF subfamily, the ZNF91 clade, has expanded specifically in primates to compri… more

Date: September 28, 2005

Creator: Hamilton, A T; Huntley, S; Tran-Gyamfi, M; Baggott, D; Gordon, L & Stubbs, L