Chapter 8: Selective Stoichiometric and Catalytic Reactivity in the Confines of a Chiral Supramolecular Assembly
Description:
Nature uses enzymes to activate otherwise unreactive compounds in remarkable ways. For example, DNases are capable of hydrolyzing phosphate diester bonds in DNA within seconds,[1-3]--a reaction with an estimated half-life of 200 million years without an enzyme.[4] The fundamental features of enzyme catalysis have been much discussed over the last sixty years in an effort to explain the dramatic rate increases and high selectivities of enzymes. As early as 1946, Linus Pauling suggested that enzy…
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Date:
September 27, 2007
Creator:
University of California, Berkeley; Laboratory, Lawrence Berkeley National; Raymond, Kenneth; Pluth, Michael D.; Bergman, Robert G. & Raymond, Kenneth N.
Partner:
UNT Libraries Government Documents Department