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in subjects: "Synergism"

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Basic aspects of radiation action on microorganisms. Final report for the period ending October 31, 1977. [Radioresistance of micrococcus luteus]

Progress is reported on studies on the basic aspects of radiation effects on microorganisms. Results are included from studies on the effects of uv pretreatment on the survival of ..gamma..-irradiated micrococcus luteus and uv-induced radioresistance to bacteriophage.

Date: December 1, 1977

Creator: Pollard, E.C.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Size selective synergism by crown ethers in the extraction of alkali metals by di(2-ethylhexyl) phosphoric acid

Although the macrocyclic polyethers, known as crown ethers, complex metal ions and do so preferentially according to the size correspondance between the ion and the crown ether cavity, their usefulness as liquid-liquid extraction reagents has been limited by the necessity of solubilizing the anion in the organic phase. The common mineral acid anions are difficult to transfer to the organic phase and organophilic anions are expensive or impractical. A method is described that avoids this problem… more

Date: January 1, 1980

Creator: McDowell, W.J.; Kinard, W.F. & Shoun, R.R.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Mammary carcinogenesis in rats: basic facts and recent results in Brookhaven

Some research results from experiments investigating neutron-induced mammary carcinogenesis in rats are presented. The additive effects of neutrons and 3-methylcholanthrene on mammary adenocarcinoma were determined. Synergism between diethylstilbestrol and neutrons was likewise studied. Differences in mammary neoplastic response between strains of laboratory rats was also investigated. (ACR)

Date: January 1, 1982

Creator: Shellabarger, C.J.; Stone, J.P. & Holtzman, s.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Air pollutant interactions with vegetation: research needs in data acquisition and interpretation

The objective of this discussion is to consider problems involved in the acquisition, interpretation, and application of data collected in studies of air pollutant interactions with the terrestrial environment. Emphasis will be placed on a critical evaluation of current deficiencies and future research needs by addressing the following questions: (1) which pollutants are either sufficiently toxic, pervasive, or persistent to warrant the expense of monitoring and effects research; (2) what are t… more

Date: January 1, 1980

Creator: Lindberg, S. E. & McLauglin, S. B.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Biological effects of static magnetic fields: a selective review with emphasis on risk assessment

Rather than focusing on literature per se, the current study determines the status of magnetic field information that is applicable to risk assessment. Hence, an attempt is made to identify both the literature that is useful to the goal of risk assessment and a framework within which risk assessment methodologies can be derived. From this selected review, it is concluded that three areas exist for which adequate information can be found to begin modelling: disease induction, reproduction and de… more

Date: April 1, 1982

Creator: Easterly, C. E.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Study of the radiation effects on nucleic acids and related compounds. Progress report, August 15, 1976--November 14, 1977

The effects of ionizing radiation on nucleic acids and components were studied in vitro. Our approach involves four levels of operation and progress is being made at each stage. First, procedures were established to separate and purify three reactive radiation products from thymidine. Second, improved methods of synthesizing trans-glycols of pyrimidines were developed, and a new method for the stereospecific synthesis of cis-glycol of pyrimidines was realized. Thirdly, the Ames Salmonella test … more

Date: August 1, 1977

Creator: Wang, S. Y.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Metabolism and biological effects of alpha-emitting radionuclides

The emphasis of much of the current and planned research on the toxicity of alpha-emitting radionuclides is directed toward the complexities of actual and potential conditions of occupational environmental exposures of human beings. These, as well as the more limited studies on mechanisms of biological transport and effects, should increase our ability to predict health risks more accurately and to deal more confidently with human exposures, if and when they occur.

Date: May 1, 1979

Creator: Bair, W. J.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Encapsulation of hazardous wastes into agglomerates

The objective of this study was to investigate the feasibility of using the cementitious properties and agglomeration characteristics of coal conversion byproducts to encapsulate and immobilize hazardous waste materials. The intention was to establish an economical way of co-utilization and co-disposal of wastes. In addition, it may aid in the eradication of air pollution problems associated with the fine-powdery nature of fly ash. Encapsulation into agglomerates is a novel approach of treating… more

Date: January 28, 1992

Creator: Guloy, A.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Exploratory coprocessing research

The objectives of this project were to (1) study the scope of the beneficial effects of hydrothermal pretreatment of coal on subsequent conversion, (2) identify and study the chemical or physical causes of this effect, and (3) attempt to elucidate the chemistry responsible for any coal-resid synergisms.

Date: September 5, 1991

Creator: Hirschon, A. S.; Tse, D. S.; Malhotra, R.; McMillen, D. F. & Ross, D. S.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Synthetic fossil fuel technologies: health problems and intersociety cooperation

The potential health impacts of synthetic fossil fuel products are considered mainly in terms of complex and potentially carcinogenic mixtures of polynuclear aromatic (PNA) compounds. These components of oils and tars present an especially perplexing range of problems to those concerned with health protection. The nature of these problems, such as multifactorial exposure, are discussed within a framework of current and future standards to regulate human exposure. Some activities of government a… more

Date: January 1, 1979

Creator: Gammage, R B & Turner, J E

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Effects of chemical carcinogens of hemopoiesis, immunopoiesis and viral oncogenesis. Technical progress report, December 1, 1977--September 30, 1978. [Mechanisms of potentiation of viral leukemogenesis by MMS, benzopyrene, and DMBA]

During the past year we have concentrated on defining the circumstances under which methyl methanesulfonate (MMS), benzo(a) pyrene (BP), and 7,12-dimethylbenz(a)anthracene (DMBA) interact with Friend virus (FLV) to produce leukemia. The optimum scheduling for each and also the effective dose levels of the chemicals have been partially determined. There are at least three critical factors which govern whether or not a leukemogenic interaction can be shown between the chemical agents and the viru… more

Date: October 1, 1978

Creator: OKunewick, J.P.; Raikow, R.B. & Meredith, R.F.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Fast-neutron dosimetry. Progress report, 1 July 1982-30 June 1983

Several aspects of neutron and related photon radiological physics are being actively investigated. These research topics relate to measurement techniques, basic data values and theoretical discussions. In addition, a modest radiobiological effort is pursued concurrently. The unique coupled neutron/photon source provides an excellent tool for this latter work.

Date: January 1, 1983

Creator: DeLuca, P.M. Jr.; Attix, F.H. & Gould, M.N.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Influence of fuel sulfur on the selective reduction of NO by NH/sub 3/

The selective reduction of NO by NH/sub 3/ addition has been studied in a lean-burning oil fired laboratory combustion tunnel with pyridine and thiophene added to the fuel oil. Two distinct, but interrelated effects were observed. The conversion of a fixed amount of fuel nitrogen to NO in the flame increased as the fuel sulfur concentration increased. In the post-combustion gases, there was a shift in the temperature dependence of the reduction process when the sulfur combustion products were p… more

Date: October 1, 1981

Creator: Lucas, D. & Brown, N.J.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Effects of Sulfur Dioxide and Nitrogen Dioxide on Vegetation: Six Month Progress Report, 1 April-30 September 1979

Progress in research on the effects of sulfur dioxide and nitrogen dioxide on plants is presented. Specific areas of investigation include: effects of NO/sub 2/ on the phytotoxicity of SO/sub 2/; interactions of air pollutants, plants and plant pathogens; effects of SO/sub 2/ on plant-insect interactions; mode of action and metabolism of SO/sub 2/ in plants. (ACR)

Date: October 1, 1979

Creator: Weinstein, L. H.; McCune, D. C.; MacLean, D. C.; Laurence, J. A.; Amundson, R. G.; Alscher-Herman, Ruth et al.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Role of base damage in aberration formation: interaction of aphidicolin and x-rays

The base analog cytosine arabinoside (CA) is an inhibitor of DNA synthesis that is able to induce chromosomal aberrations not only in the DNA synthetic (S) phase of the cell cycle but in cells in the pre- (G/sub 0/ or G/sub 1/) and in the post-DNA-synthetic (G/sub 2/) phases of the cell cycle as well. Incubation of human peripheral lymphocytes in CA following either G/sub 0/ or G/sub 2/ x irradiation causes a synergistic increase in chromosomal aberration frequency. CA is believed to preferenti… more

Date: January 1, 1981

Creator: Bender, M. A. & Preston, R. J.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Decomposition of radiational effects of model feedbacks

Three separate doubled CO/sub 2/ experiments with the statistical dynamic model are used to illustrate efforts to study the climate dynamics, feedbacks, and interrelationships of meteorological parameters by decomposing and isolating their individual effects on radiation transport.

Date: August 1, 1981

Creator: Ellsaesser, Hugh W.; MacCracken, Michael C.; Potter, Gerald L. & Mitchell, Connee S.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Pathogenic mechanism in lung fibrosis. [Synergistic effects of BHT, O/sub 2/, and x rays in mice]

The purpose of the study was to examine whether an interaction between two agents causing alveolar epithelial damage would produce lung fibrosis. In mouse lung, intraperitoneal injection of the antioxidant butylated hydroxytoluene causes diffuse alveolar type I cell necrosis, followed by proliferation of type II alveolar cells. In animals exposed to 70% O/sub 2/ or 100-200 rad x rays during the phase of type II cell proliferation following BHT, diffuse interstitial lung fibrosis developed withi… more

Date: January 1, 1979

Creator: Witschi, H.; Haschek, W. M.; Meyer, K. R.; Ullrich, R. L. & Dalbey, W. E.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

DNA repair in mammalian cells exposed to combinations of carcinogenic agents. [uv radiation; AAAF; 4-NQO; DMBA-epoxide; ICR-170]

Cells defective in one or more aspects of repair are killed and often mutagenized more readily than normal cells by DNA damaging agents, and humans whose cells are deficient in repair are at an increased carcinogenic risk compared to normal individuals. The excision repair of uv induced pyrimidine dimers is a well studied system, but the details of the steps in this repair system are far from being understood in human cells. We know that there are a number of chemicals that mimic uv in that nor… more

Date: January 1, 1979

Creator: Setlow, R.B. & Ahmed, F.E.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Solvent and chemical-reaction effects in supercritical extraction of coal. Fourth quarterly technical progress report, 1 June-31 August 1982

Supercritical gas extraction experiments were carried out with various organic solvents, including a homologous series of n-paraffins from pentane to dodecane. Some experiments involved mixtures and others involved polar molecules, different density and often covered a pressure range at a constant 400/sup 0/C. Correlations were developed and compared with conclusions of previous authors. The results are quite detailed and, in many cases, did not agree with those of previous authors. (LTN)

Date: January 1, 1982

Creator: Vasilakos, N. P.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Polymer-based separations: Synthesis and application of polymers for ionic and molecular recognition

Polymer-based separations have utilized resins such as sulfonic, acrylic, and iminodiacetic acid resins and the XAD series. Selective polymeric reagents for reaction with a targeted metal ion were synthesized as polymers with two different types of functional groups, each operating on the ions through a different mechanism. There are 3 classes of DMBPs (dual mechanism bifunctional polymers). Research during this period dealing with metal ion recognition focused on two of these classes (reductio… more

Date: January 1, 1992

Creator: Alexandratos, S.D.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Evaluation of Coal Minerals and Metal Residues as Coal-Liquefaction Catalysts. Final Report

The catalytic activity of various minerals, metallic wastes, and transition metals was investigated in the liquefaction of various coals. The effects of coal type, process variables, coal cleaning, catalyst addition mode, solvent quality, and solvent modification on coal conversion and oil production were also studied. Coal conversion and oil production improved significantly by the addition of pyrite, reduced pyrite, speculite, red mud, flue dust, zinc sulfide, and various transition metal com… more

Date: February 1, 1982

Creator: Garg, D.; Givens, E. N.; Schweighardt, F. K.; Tarrer, A. R.; Guin, J. A.; Curtis, C. W. et al.

Item Type: Report

Partner: UNT Libraries Government Documents Department

open access

Influence of fuel sulfur on the selective reduction of NO by NH/sub 3/

More intensive regulations of the emissions of nitrogen oxides from stationary combustion sources have prompted the innovation and characterization of new control technologies suitable for applications in utilities. One of the more recent and attractive abatement technologies is the Thermal DeNO/sub x/ process which has been described by Lyon and Longwell. This process removes NO by selectively reducing it with NH/sub 3/ added to the post-combustion gases containing excess oxygen. This process … more

Date: January 1, 1981

Creator: Lucas, D. & Brown, N.J.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

The use of supercritical fluid processes for detoxification of pollutants using geopressured-geothermal fluids

This paper proposes the development of an engineered interface between a geopressured-geothermal resource and a supercritical water oxidation (SCWO) process which destroys hazardous organic wastes. The objectives of this study are to show economic advantages in linking the geopressured-geothermal resource with an SCWO process: to destroy hazardous organic waste; to produce power with the combined energy content of the geopressured-geothermal resource and the SCWO process; to use the available e… more

Date: January 1, 1991

Creator: Shapiro, C.

Item Type: Article

Partner: UNT Libraries Government Documents Department

open access

Genotoxic effects of sunlight-activated waste waters

Natural sunlight induces a genotoxic response in cultured CHO cells pre-treated with shale oil retort process water. Near ultraviolet light (NUV) component of the solar spectrum is the apparent radiation responsible for photoactivation. Cultured human skin fibroblasts are acutely sensitive to the genotoxic effects of photoactivated process water. The mutagenic potential of photoactivated process water in human cells is the same as that witnessed for an equivalent killing dose of the potent skin… more

Date: January 1, 1981

Creator: Strniste, G.F.; Chen, D.J. & Okinaka, R.T.

Item Type: Article

Partner: UNT Libraries Government Documents Department