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Ophthalmologic survey of atomic bomb survivors in Japan, 1949. Atomic bomb radiation cataract case report with histopathologic study. Medical examination of Hiroshima patients with radiation cataracts

Description: This document contains 3 reports dealing with the delayed effects of radiation on the eyes of survivors of the atomic explosions in Hiroshima and Nagasaki. In the first study, 1000 persons who were listed as having been in the open and within two kilometers of the hypocenter at the time of the explosion were selected at random from the census files of the Atomic Bomb Casualty Commission for study. In addition, 231 others, comprising the total available number of surviving persons listed at pres… more
Date: January 1, 1959
Creator: Cogan, D.G.; Martin, S.F.; Kimura, S.J.; Ikui, Hiroshi & Fillmore, Paul G.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Physiological imaging with PET and SPECT in Dementia

Description: Dementia is a medical problem of increasingly obvious importance. The most common cause of dementia, Alzheimer's disease (AD) accounts for at least 50% of all cases of dementia, with multi-infarct dementia the next most common cause of the syndrome. While the accuracy of diagnosis of AD may range from 80 to 90%, there is currently no laboratory test to confirm the diagnosis. Functional imaging techniques such as positron emission tomography (PET) and single photon emission computed tomography (… more
Date: October 1, 1989
Creator: Jagust, W.J. (California Univ., San Francisco, CA (United States). Dept. of Neurology Lawrence Berkeley Lab., CA (United States))
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Los Alamos Life Sciences Division's biomedical and environmental research programs. Progress report, January-December 1980

Description: Highlights of research progress accomplished in the Life Sciences Division during the year ending December 1980 are summarized. Reports from the following groups are included: Toxicology, Biophysics, Genetics; Environmental Pathology, Organic Chemistry, and Environmental Sciences. Individual abstracts have been prepared for 46 items for inclusion in the Energy Data Base. (RJC)
Date: September 1, 1981
Creator: Holland, L. M.; Stafford, C. G. & Bolen, S. K. (comps.)
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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THE METABOLSIM AND TOXICITY OF RADIUM-223 IN RATS

Description: This report covers studies of the excretion and retention of 'tracer' and toxic doses of the 11.2-day Ra{sup 223} isotope, its acute toxicity (organ weight changes, gross and microscopic pathology, and Fe{sup 59} utilization by the bone marrow), and long-term histopathological changes and alterations in the hemogram.
Date: February 21, 1958
Creator: Durbin, Patricia; Durbin, Patricia W.; Asling, C. Willet.; Jeung, Nylan; Williams, Marilyn H.; Post, James. et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Deletion of ultraconserved elements yields viable mice

Description: Ultraconserved elements have been suggested to retainextended perfect sequence identity between the human, mouse, and ratgenomes due to essential functional properties. To investigate thenecessities of these elements in vivo, we removed four non-codingultraconserved elements (ranging in length from 222 to 731 base pairs)from the mouse genome. To maximize the likelihood of observing aphenotype, we chose to delete elements that function as enhancers in amouse transgenic assay and that are near ge… more
Date: July 15, 2007
Creator: Ahituv, Nadav; Zhu, Yiwen; Visel, Axel; Holt, Amy; Afzal, Veena; Pennacchio, Len A. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Investigation of Head Burns in Adult Salmonids : Phase 1, Examination of Fish at Lookingglass Hatchery in 1996 : Addendum to Final Report.

Description: This information is an addendum to the report 'Investigation of Head Burns in Adult Salmonids, Phase 1: Examination of Fish at Lower Granite Dam, July 2, 1996' by Ralph Elston because there may be relevant observations included here. The author of this document participated in the examinations at Lower Granite Dam described in that report. Because of Endangered Species Act issues, the Rapid River stock of spring chinook salmon reared at Lookingglass Hatchery on the Grande Ronde River in northea… more
Date: November 1, 1996
Creator: Groberg, Warren J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Introduction to veterinary clinical oncology

Description: Veterinary clinical oncology involves a multidisciplinary approach to the recognition and management of spontaneously occurring neoplasms of domestic animals. This requires some knowledge of the causes, incidence, and natural course of malignant disease as it occurs in domestic species. The purpose of this course is to acquaint you with the more common neoplastic problems you will encounter in practice, so that you can offer your clients an informed opinion regarding prognosis and possible ther… more
Date: October 1, 1991
Creator: Weller, R. E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Delayed effects of neutron irradiation on central nervous system microvasculature in the rat

Description: Pathologic examination of a series of 14 patients with malignant gliomas treated with BNCT showed well demarcated zones of radiation damage characterized by coagulation necrosis. Beam attenuation was correlated with edema, loss of parenchymal elements, demyelination, leukocytosis, and peripheral gliosis. Vascular disturbances consisted of endothelial swelling, medial and adventitial proliferation, fibrin impregnation, frequent thrombosis, and perivascular inflammation. Radiation changes appeare… more
Date: January 1, 1988
Creator: Goodman, J.H.; McGregor, J.M.; Clendenon, N.R.; Gordon, W.A.; Yates, A.J.; Gahbauer, R.A. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Los Alamos Life Sciences Division's biomedical and environmental research programs. Progress report, January-December 1981. [Leading abstract]

Description: This report summarizes research and development activities of the Los Alamos Life Sciences Division's Biomedical and Environmental Research program for the calendar year 1981. Individual reports describing the current status of projects have been entered individually into the data base.
Date: October 1, 1982
Creator: Holland, L.M. & Stafford, C.G. (comps.)
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Marker evaluation of human breast and bladder cancers

Description: We are investigating multiple markers in human breast and bladder cancers. Our aim is to identify markers that are clinically relevant and that contribute to our understanding of the disease process in individual patients. Good markers accurately assess the malignant potential of a cancer in an individual patient. Thus, they help identify those cancers that will recur, and they may be used to predict more accurately time to recurrence, response to treatment, and overall prognosis. Therapy and p… more
Date: November 2, 1990
Creator: Mayall, B. H.; Carroll, P. R.; Chen, Ling-Chun; Cohen, M. B.; Goodson III, W. H.; Smith, H. S. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Investigation of independence in inter-animal tumor-type occurrences within the NTP rodent-bioassay database

Description: Statistically significant elevation in tumor incidence at multiple histologically distinct sites is occasionally observed among rodent bioassays of chemically induced carcinogenesis. If such data are to be relied on (as they have, e.g., by the US EPA) for quantitative cancer potency assessment, their proper analysis requires a knowledge of the extent to which multiple tumor-type occurrences are independent or uncorrelated within individual bioassay animals. Although difficult to assess in a sta… more
Date: May 1, 1993
Creator: Bogen, K. T. & Seilkop, S.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Studies of acute and chronic radiation injury at the Biological and Medical Research Division, Argonne National Laboratory, 1970-1992: The JANUS Program Survival and Pathology Data

Description: A research reactor for exclusive use in experimental radiobiology was designed and built at Argonne National Laboratory in the 1960`s. It was located in a special addition to Building 202, which housed the Division of Biological and Medical Research. Its location assured easy access for all users to the animal facilities, and it was also near the existing gamma-irradiation facilities. The water-cooled, heterogeneous 200-kW(th) reactor, named JANUS, became the focal point for a range of radiobio… more
Date: February 1995
Creator: Grahn, D.; Wright, B. J.; Carnes, B. A.; Williamson, F. S. & Fox, C.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

ORNL `90

Description: This overview of research conducted at ORNL in 1991 presents information on the subjects of biology, physics, and the environment. Specific topics include gene mutations in kidney disease, technology assessments in thermonuclear fusion, submarine hunting technology, ozone-safe refrigerants, optical data storage via surface enhanced raman spectroscopy, and waste mitigating microbes. (GHH)
Date: December 31, 1990
Creator: Anderson, T.; Barnes, D. & Jefferson, J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

MEG studies of human vision: Retinotopic organization of V1

Description: A primary goal of noninvasive studies of human vision is to identify and characterize multiple visual areas in the human brain analogous to those identified in studies of nonhuman primates. By combining functional MEG measurements with images of individual anatomy derived from MRI, the authors hope to determine the location and arrangement of multiple visual areas in human cortex and to probe their functional significance. The authors have identified several different visual areas thus far whic… more
Date: December 31, 1993
Creator: Aine, C.; George, J.; Ranken, D.; Best, E.; Tiee, W.; Vigil, V. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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The significant human-animal bond: Pets with cancer

Description: Veterinarians have responsibilities to both the animal and its owner. In the past several years there has been an increased awareness and concern about human-animal bonds. As a result, we have begun to appreciate the nature, strength, and significance of bonds that develop between humans and companion animals. It is typical for a pet to be perceived as and treated as a member of the family and as a result, animals provide special and beneficial relationships for many years. It is partly because… more
Date: March 1, 1994
Creator: Weller, R. E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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A model for the immune system response to HIV: AZT treatment studies

Description: We use mathematical models to describe the interaction of the immune system with the human immunodeficiency virus (HIV). Our model includes T-lymphocytes and macrophages, cells which can be infected with the virus. Using our model we compare the efficacy of AZT treatments given at different stages of disease progression in order to predict when treatment should be initiated.
Date: May 1, 1993
Creator: Kirschner, D. E. & Perelson, A. S.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Diagnosis and management of endocrine gland neoplasmas. Revision 1

Description: Functional and nonfunctional neoplasms of the endocrine glands constitute some of the more challenging diagnostic and therapeutic problems in veterinary cancer medicine. This discussion will focus on the clinical signs and syndromes associated with neoplasms of the thyroid, adrenal, and parathyroid glands, and pancreas in companion animals and will concentrate on the mechanisms producing the clinical signs, diagnosis, staging, therapy and prognosis.
Date: March 1, 1994
Creator: Weller, R. E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Urogenital tumors

Description: An overview is provided for veterinary care of urogenital tumors in companion animals, especially the dog. Neoplasms discussed include tumors of the kidney, urinary bladder, prostate, testis, ovary, vagina, vulva and the canine transmissible venereal tumor. Topics addressed include description, diagnosis and treatment.
Date: March 1, 1994
Creator: Weller, R. E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Theoretical and experimental investigations of elastic scattering spectroscopy as a potential diagnostic for tissue pathologies

Description: The spectral distribution of the diffuse reflectance of five sizes of polystyrene microspheres has been measured with an elastic scatter spectrometer designed for optical biopsy of living tissue. The microsphere sizes are representative of the suspected scattering centers in living tissue. The experiment data are discussed and interpreted in the framework of Mie scattering theory and Monte-Carlo transport analysis. Present results support the assertion that Mie theory is necessary to describe t… more
Date: April 1, 1994
Creator: Boyer, J.; Mourant, J. R. & Bigio, I. J.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Intrathoracic neoplasia: Epidemiology and etiology

Description: Neoplasms of the thorax encompass those derived from the thoracic wall, trachea, mediastinum, lungs and pleura. They represent a wide variety of lesions including benign and malignant tumors arising from many tissues. The large surface area, 60 to 90 m{sup 2} in man, represented by the respiratory epithelium and associated thoracic structures are ideal targets for carcinogens carried by inspired air. The topic of discussion in this report is the epidemiology, etiology, and mechanisms of spontan… more
Date: May 1, 1992
Creator: Weller, R. E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Correlation of chromosome patterns in human leukemic cells with exposure to chemicals and/or radiation. Comprehensive progress report, July 1991--June 1994

Description: This comprehensive progress report provides a synopsis of major research accomplishments during the years of 1991-1994, including the technical aspects of the project. The objectives and accomplishments are as follows: 1. Defining the chromosome segments associated with radiation and chemically-induced leukemogenesis (treatment-related acute myeloid leukemia, t-AML); A. Continued genetic analysis of chromosomes 5 and 7, B. Correlation of treatment with balanced and unbalanced translocations. 2.… more
Date: June 1, 1994
Creator: Rowley, J. D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Method for distinguishing normal and transformed cells using G1 kinase inhibitors

Description: A G{sub 1} phase kinase inhibitor is applied in a low concentration to a population of normal and transformed mammalian cells. The concentration of G{sub 1} phase kinase inhibitor is selected to reversibly arrest normal mammalian cells in the G{sub 1} cell cycle without arresting growth of transformed cells. The transformed cells may then be selectively identified and/or cloned for research or diagnostic purposes. The transformed cells may also be selectively killed by therapeutic agents that d… more
Date: December 31, 1991
Creator: Crissman, H. A.; Gadbois, D. M.; Tobey, R. A. & Bradbury, E. M.
Item Type: Refine your search to only Patent
Partner: UNT Libraries Government Documents Department
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