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in creator/contributor: "Lacko, Andras G."  
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Sensitive Microtiter Assays for NAD, NADP and Protein Quantification in Human Lymphocytes

Description: Intracellular levels of NAD are of renewed interest in clinical and basic science research due to the new discovery of enzymes which utilize NAD as a substrate. Microtiter assays for the determination of NAD, NADP and protein were developed as modifications of previously published methods. The resulting assays are simple, cost effective and sensitive. An improved method of isolating lymphocytes was also developed. The resultant procedure requires one hour and removes greater than 99.9% of the p… more
Date: May 1990
Creator: Johnson, James, 1964-
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Studies of the Interaction of LCAT with Lipoprotein Substrates in HDL Deficient Plasma Systems

Description: Enzymatic and lipid transfer reactions involved in reverse cholesterol transport were studied in HDL deficient plasma systems. Fasting plasma samples were obtained from control and cholesterol fed guinea pigs as well as from a fish eye disease patient and were used to localize the enzyme LCAT among plasma lipoproteins (VLDL, LDL, and HDL). In both guinea pig and fish eye disease patient plasma, the LCAT activity was found in association with the HDL type particles. Cholesterol feeding in guinea… more
Date: August 1989
Creator: Paranjape, Sulabha
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Studies on Poly (ADP-ribose) Synthesis in Lymphocytes of Systemic Lupus Erythematosus Patients

Description: A method for assaying poly (ADP-ribose) polymerase (PADPRP) activity in lymphocytes of systemic lupus erythematosus (SLE) patients has been developed. Using this method, PADPRP activity has been studied in lymphocytes from 15 patients and 13 controls. The mean activity in SLE lymphocytes was significantly lower than that in controls and 60% of the SLE patients demonstrated activities below the minimum of the control population. Possible mechanisms for this altered metabolism were investigated. … more
Date: December 1991
Creator: Chen, Hai-Ying
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
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