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A fast, flexible algorithm for calculating correlations in Fluorescence Correlation Spectroscopy

Description: A new algorithm is introduced for computing correlations of photon arrival time data acquired in single-molecule fluorescence spectroscopy and fluorescence correlation spectroscopy (FCS). The correlation is first rewritten as a counting operation on photon pairs. For each photon, the contribution to the correlation function for each subsequent photon is calculated for arbitrary bin spacings of the correlation time lag. By retaining the bin positions in the photon sequence after each photon, the… more
Date: October 13, 2005
Creator: Laurence, T; Fore, S & Huser, T
Partner: UNT Libraries Government Documents Department
open access

Counting constituents in molecular complexes by fluorescence photon antibunching

Description: Modern single molecule fluorescence microscopy offers new, highly quantitative ways of studying the systems biology of cells while keeping the cells healthy and alive in their natural environment. In this context, a quantum optical technique, photon antibunching, has found a small niche in the continuously growing applications of single molecule techniques to small molecular complexes. Here, we review some of the most recent applications of photon antibunching in biophotonics, and we provide a … more
Date: April 17, 2007
Creator: Fore, S; Laurence, T; Hollars, C & Huser, T
Partner: UNT Libraries Government Documents Department
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