Effects of Brain Injury on Primary Cilia of Glial Cells and Pericytes
Description:
Glial cells maintain homeostasis that is essential to neuronal function. Injury to the nervous system leads to the activation and proliferation of glial cells and pericytes, which helps to wall off the damaged region and restore homeostatic conditions. Sonic hedgehog is a mitogen which is implicated in injury-induced proliferation of glial cells and pericytes. The mitogenic effects of sonic hedgehog require primary cilia, but the few reports on glial or pericyte primary cilia do not agree about…
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Date:
December 2016
Creator:
Coronel, Marco V.
Partner:
UNT Libraries