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Basic aspects of radiation action on microorganisms. Final report for the period ending October 31, 1977. [Radioresistance of micrococcus luteus]

Description: Progress is reported on studies on the basic aspects of radiation effects on microorganisms. Results are included from studies on the effects of uv pretreatment on the survival of ..gamma..-irradiated micrococcus luteus and uv-induced radioresistance to bacteriophage.
Date: December 1, 1977
Creator: Pollard, E.C.
Partner: UNT Libraries Government Documents Department
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Study of the radiation effects on nucleic acids and related compounds. Progress report, August 15, 1976--November 14, 1977

Description: The effects of ionizing radiation on nucleic acids and components were studied in vitro. Our approach involves four levels of operation and progress is being made at each stage. First, procedures were established to separate and purify three reactive radiation products from thymidine. Second, improved methods of synthesizing trans-glycols of pyrimidines were developed, and a new method for the stereospecific synthesis of cis-glycol of pyrimidines was realized. Thirdly, the Ames Salmonella test … more
Date: August 1, 1977
Creator: Wang, S. Y.
Partner: UNT Libraries Government Documents Department
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Accelerated aging in combined stress environments. [Synergistic effects of thermal and radiation environments on Bacillus subtilis]

Description: Accelerated aging can be useful in estimating the lifetime of a component of interest. If under ambient conditions a single environmental variable is the predominant cause of the aging process, accelerated aging is often accomplished by raising the level of this variable above its ambient value. The relationship between the mean time to failure and the value of the accelerated environmental variable is extrapolated to ambient conditions in order to establish the ambient lifetime of the componen… more
Date: January 1, 1977
Creator: Gillen, K. T.
Partner: UNT Libraries Government Documents Department
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Combined effects of hyperthermia and radiation in cultured mammalian cells

Description: Hyperthermia (temperatures of 39/sup 0/C or higher) enhances the killing of mammalian cells by ionizing radiation (fission-spectrum neutrons and x-rays). The nature and the magnitude of the enhanced radiation killing varies with temperature and for a fixed temperature during irradiation, the enhanced lethality varies inversely with dose rate. For temperatures up to 41/sup 0/C, dose fractionation measurements indicate that hyperthermia inhibits the repair of sublethal damage. At higher temperatu… more
Date: January 1, 1977
Creator: Ben-Hur, E.; Elkind, M. M. & Riklis, E.
Partner: UNT Libraries Government Documents Department
open access

Plutonium Decorporation by Mixed Ligand Chelates. Final Report, June 2, 1976--April 15, 1977.

Description: The effects of mixed ligand chelates on the removal of /sup 239/Pu and /sup 234/Th from the tissues of mice were investigated. The primary ligands, L/sub 1/, used were mainly EDTA and DTPA, while the secondary ligands, L/sub 2/, were of the bidentate type, as, for example, catechol, salicylic acid, and benzohydroxamic acid. A suitably chosen mixed ligand system binds Pu or Th at physiological pH's about 10/sup 11/ to 10/sup 15/ times greater than EDTA or DTPA. An ultrafiltration screening proce… more
Date: April 1, 1977
Creator: Schubert, J.
Partner: UNT Libraries Government Documents Department
open access

Multiple three-decision rules for 2/sup k/-factorial simple effects. Technical report No. 8

Description: One of the problems confronted in the investigation of environmental health and in biological research more generally is the fact that organisms often respond to combinations of treatments in ways which are not predictable from the way they respond to each of these taken separately. One air pollutant may, for example, disable the respiratory tract's self cleaning mechanisms and thereby increase its sensitivity to the effects of other pollutants. It is important that laboratory experiments be ab… more
Date: March 22, 1977
Creator: Bohrer, R.; Chow, W.; Faith, R.; Joshi, V. M. & Wu, C. F.
Partner: UNT Libraries Government Documents Department
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