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Distinction between the roles of O/sub 2/ and of O/sup -//sub 2/ in biological radiodamage

Description: The paper attempts to elucidate the roles of oxygen and superoxide radical in biological damage due to ionizing radiation. Specifically, the effect of gamma radiation on the survival of T4 bacteriophage and of E. coli B has been investigated. (ACR)
Date: January 1, 1978
Creator: Samuni, A.; Chevion, M.; Halpern, Y. S.; Ilan, Y. A. & Czapski, G.
Partner: UNT Libraries Government Documents Department
open access

Endogenous retrovirus and radiation-induced leukemia in the RMF mouse

Description: The induction of myeloid leukemia in irradiated RFM/Un mice has been associated with retrovirus infection. However, two characteristics of this strain complicate efforts to define the role of the virus. This strain possesses only one inducible host range class of endogenous virus and a unique gene, in addition to the Fv-1/sup n/ locus, which specifically restricts exogenous infection by endogenous viruses. These characteristics possibly account for absence of recombinant viruses in this strain,… more
Date: January 1, 1982
Creator: Tennant, R. W.; Boone, L. R.; Lalley, P. & Yang, W. K.
Partner: UNT Libraries Government Documents Department
open access

Mechanisms in endogenous leukemia virus induction by radiation and chemicals

Description: A model of endogenous leukemia virus induction in AKR strain mouse cells based on two distinct types of alterations in cellular or proviral DNA is presented. The first type are non-repairable alterations, such as those caused by the incorporation of halogenated pyrimidines; the second type are repairable lesions, such as those caused by irradiation or certain other chemicals. The production of non-repairable lesions leads to the formation of a stable, proviral state which is dependent upon cell… more
Date: January 1, 1976
Creator: Tennant, R. W.; Rascati, R. J. & Lavelle, G. C.
Partner: UNT Libraries Government Documents Department
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