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Expression and Function of Transient Receptor Potential Ankyrin 1 Ion Channels in the Caudal Nucleus of the Solitary Tract

The article describes a study that tested and confirmed the hypothesis that TRPA1 expressed in the primary sensory afferents may modulate the function of second order NTS neurons. The expression of TRPA1 was detected in presynaptic locations, but not the somata of caudal NTS neurons that did not express TRPA1 mRNA or proteins. Moreover, caudal NTS neurons did not show somatodendritic responsiveness to TRPA1 agonists, while TRPA1 immunostaining was detected only in the afferent fibers.

Date: April 26, 2019

Creator: Feng, Lin; Uteshev, Victor V. & Premkumar, Louis S.

Item Type: Article

Partner: UNT Health Science Center

open access

Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research

This review aims to find effective phytoconstituents in cataract treatments in vitro, ex vivo, and in vivo. Scientists have focused their attention not only for anti-cataract activity in vitro, but also in ex vivo and in vivo from the review of active phytoconstituents in medicinal plants. In our present review, we identified 58 active phytoconstituents with strong anti-cataract effects at in vitro and ex vivo with lack of in vivo studies.

Date: October 26, 2018

Creator: Lim, Vuanghao; Schneider, Edward; Wu, Hongli & Pang, Iok-Hou