Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers
Description:
This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date:
May 27, 2011
Creator:
Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish