Selective Photothermolysis to target Sebaceous Glands: Theoretical Estimation of Parameters and Preliminary Results Using a Free Electron Laser Page: 26 of 35
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Lasers in Surgery and Medicine
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9Table 1. Estimated exposure parameters for selective photothermolysis of lipids
structures.Subcutaneous fat Sebaceous glands
Size (mm) > 5 (typically) 0.26 0.11'
Thermal relaxation time (t')(seconds) > 20 (typically) ~ 0.06 - 0.100*
Depth of location (mm) ~ 2.0 (typically) 0.5 0.2
pc (J.cm-3.oC-1) ~2.1 (27) 3.57
Temperature raise (AT) ( C) 20 50
~1210 nm band
Pa (cm1) 1.52 (15) 2.2*
Transmittance to target (T) -15.6% ~33.1%
Estimated fluence (J/cm2) -120 (15)_177 ** ~ 245 **
~1720 nm band
Pa (cm-1) 10.32 (15) 8.1*
Transmittance to target (T) 11% 32.8%1
Estimated fluence (J/cm2) - 37 ** ~ 67 **
fa: absorption coefficient.
* Data from this study.
** Estimated incident fluence (FO), FO AT.pc/ pa.T; where AT: temperature raise, pc:
heat capacity, pa: coefficient of absorption, T: transmittance through the skin.
Estimated using Monte Carlo and IAD models.12
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60John Wiley & Sons, Inc.
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Fernanda Sakamoto, Apostolos Doukas, William Farinelli, Zeina Tannous, Michelle D. Shinn, Stephen Benson, Gwyn P. Williams, H. Dylla, Richard Anderson. Selective Photothermolysis to target Sebaceous Glands: Theoretical Estimation of Parameters and Preliminary Results Using a Free Electron Laser, article, December 1, 2011; Newport News, Virginia. (https://digital.library.unt.edu/ark:/67531/metadc845167/m1/26/: accessed July 16, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.