Fungal Antigens and Fungal Disease: An Alkali-Soluble, Water Soluble Antigen from Coccidioides immitis and Coccidioidomycosis Page: 3
viii, 204 leaves : ill.View a full description of this dissertation.
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Diagnosis of coccidioidomycosis is difficult. Serum samples from thirty-
seven patients with proven coccidioidomycosis were analyzed by GLC for the
presence of 3-0-methyl mannose; a sugar unique to the cell wall of C. immitis.
This unique methylated sugar was present in all thirty-seven sera tested.
Analysis of sera from controls and from patients with aspergillosis, blasto-
mycosis, candidiasis, and histoplasmosis did not reveal the presence of 3-0-
methyl mannose. Therefore, 3-0-methyl mannose can serve as a unique marker
for the diagnosis of coccidioidomycosis by GLC.
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Fleming, William H. (William Harold). Fungal Antigens and Fungal Disease: An Alkali-Soluble, Water Soluble Antigen from Coccidioides immitis and Coccidioidomycosis, dissertation, December 1983; Denton, Texas. (https://digital.library.unt.edu/ark:/67531/metadc331669/m1/3/: accessed July 17, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; .