Impact of Anti-S2 Peptides on a Variety of Muscle Myosin S2 Isoforms and Hypertrophic Cardiomyopathy Mutants Revealed by Fluorescence Resonance Energy Transfer and Gravitational Force Spectroscopy Page: VI
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LIST OF TABLES
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Table 3.1: Calculated Critical Transfer Distance Parameters ..................................................44
Table 3.2: Experimental measurement of separation distance between the acceptor probe and the
donor probe ................................................................................................................................... 46
Table 3.3: Summary of dissociation constant and correlation coefficient of FRET experiments 53
Table 3.4: Summary of Student's test for FRET experiments..................................................53
Table 3.5: Summary of fitted parameters for GFS experiments correlated with the
thermodynamic equation............................................................................................................... 56
Table 3.6: Summary of myosin S2 molecular uncoiling length measured with GFS in presence
and absence of anti-S2 peptides for all myosin S2 Isoforms and FHC mutant................61
Table 3.7: Summary of P-values of t-test and Wilcoxon-Mann-Whitney test................62vi
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Aboonasrshiraz, Negar. Impact of Anti-S2 Peptides on a Variety of Muscle Myosin S2 Isoforms and Hypertrophic Cardiomyopathy Mutants Revealed by Fluorescence Resonance Energy Transfer and Gravitational Force Spectroscopy, dissertation, August 2020; Denton, Texas. (https://digital.library.unt.edu/ark:/67531/metadc1707335/m1/8/: accessed July 17, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; .