Multi-Omics Based Investigation of Distinct Early Oxidative Stress Responses of Saccharomyces cerevisiae to Various Oxidants
Description:
The early signaling mechanism(s) that control oxidant perception and signal transduction leading to activation of the antioxidant defense response and survival mechanisms tailored toward specific oxidative insult remains unknown. Here, we identified early changes in metabolome and proteome of S. cerevisiae in response to hydrogen peroxide, menadione, cumene hydroperoxide, and diamide. Firstly, global untargeted LC–MS/MS analysis allowed us to identify 196 proteins in response to hydrogen peroxi…
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Date:
May 2021
Creator:
Pandey, Prajita