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4-Ethoxymethylphenol: a novel phytoestrogen that acts as an agonist for human estrogen receptors.
Access: Use of this item is restricted to the UNT Community
Date: December 2001
Creator: Pearce, Virginia
Description: Estrogen is the natural agonist of the estrogen receptor (ER). However, certain plant-derived compounds or phytoestrogens have been identified that mimic estrogens and act as agonists and/or antagonists of ERs, depending on subtype and target tissue. Understanding how phytoestrogens interact with ERs, and therefore effect the estrogenic response, may prove beneficial in hormone replacement therapy and in the prevention and treatment of hormone-related diseases. Using Thin Layer Chromatography, gas chromatography/mass spectrometry (GC/MS), and proton nuclear nagnetic resonance (HNMR), I identified 4-ethoxymethylphenol (4EM) found in Maclura pomifera. While most phytoestrogens are heterocyclic compounds, 4EM is a simple phenol that acts as an agonist of ER-alpha and -beta in HeLa and MCF-7 cells. To study the effect of 4EM on ER-alpha and -beta activity, I performed transient transfection assays and showed that 4EM activates ER dependent gene transcription in a dose dependent manner in both ER subtypes. Further, 4EM- mediated transcription in ER-alpha, like estrogen, was enhance in the presense of co-activators, SRC-1 (steroid receptor coactivator-1), CBP (CREB binding proteins), and E6-AP (E6-associated protein) and inhibited by trans-4- hydroxytamoxifen (4HT). I found that 4EM was specific for ER and did not activate transcription of the progesterone receptor in HeLa cells.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc3003/
An 8-step program: Shaping and fixed-time food delivery effects on several approximations and undesired responses in goats.
Date: May 2003
Creator: Fernandez, Eduardo J.
Description: This study investigated the effects of a shaping program for halter training across 8 steps in the program and 4 trial-terminating, or "undesirable," responses. Three La Mancha goats (Capra hircus) located at the Frank Buck Zoo in Gainesville, Texas were used for the study. A fixed-time 15 s (FT-15 s) was used during the baseline conditions, to examine the effects of response contingent and response-independent food deliveries, as well as to examine what preliminary steps might not necessarily have to be shaped. All 3 goats successfully learned to allow the halter to be placed on them and to lead on the halter, although 2 of the 3 goats required an additional task analysis for the fifth step to further break down that approximation. Several of the early steps selected by the researchers were not necessary to complete the program, as determined by the baseline condition.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc4219/
24, Lost, and Six Feet Under: Post-traumatic television in the post-9/11 era.
Date: May 2008
Creator: Anderson, Tonya
Description: This study sought to determine if and how television texts produced since September 11, 2001, reflect and address cultural concerns by analyzing patterns in their theme and narrative style. Three American television serials were examined as case studies. Each text addressed a common cluster of contemporary issues such as trauma, death, and loss.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc6137/
100% Renewable Energy - and Beyond - for Cities
Date: March 2010
Creator: Droege, Peter
Description: This booklet sketches out the options and the processes that have started to transform urban energy systems. The document promotes carbon neutrality for communities and cities and argues that even the largest cities can make this transition, drawing on renewable energy supplies from within their boundaries, as well as from farther away. In addition to assuring urban energy security, these developments can also stimulate the growth of a very large new green economy sector.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc13721/
161 Glass: Site Specific Music in an Artistic Context
Date: May 2010
Creator: Rusnak, Christina S.
Description: The composition 161 Glass is a 17-minute musical work with percussion, wind and brass instruments in which the intersection of mid-century architecture, and the art and culture of a dynamic city are inextricably linked. Through this paper, I explore the process of composing a musical work in relationship to the significance of site specific context. The paper begins by defining the concept of site specific art works; then reviews the discourse of the intersection of art, music and architecture. I then delve into the cultural and geographic context surrounding this project from the modern era through the present, and how those perspectives apply to the building and my piece. I reveal how the composition relates the musical ideas to the site. Finally, I describe the collaborative process between myself, the musicians and the Dallas Contemporary staff.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc28472/
The 1986 National Endowment for the Arts Commission: An introspective analysis of two marimba works, Reflections on the Nature of Water by Jacob Druckman and Velocities by Joseph Schwantner, together with three recitals of selected works by Keiko Abe, Christopher Deane, Peter Klatzow, Wayne Siegel, Gitta Steiner and others.
Date: August 2005
Creator: Fang, I-Jen
Description: The marimba is rapidly achieving greater importance as a solo percussion instrument. Solo compositions for the marimba have been commissioned and performed only in the last sixty years. The 1986 National Endowment for the Arts Solo Marimba Commission is considered one of the most important commissioning projects in the history of marimba literature. Two compositions created through this project, Velocities by Joseph Schwantner and Reflections on the Nature of Water by Jacob Druckman have become two of the most influential works in contemporary marimba music. This thesis will focus on a historical perspective of the project, as well as theoretical aspects and performance issues related to these two compositions. The National Endowment for the Arts (NEA) issued a consortium commissioning grant through the Percussive Arts Society (PAS) in 1986 to three internationally renowned marimbists, William Moersch, Leigh Howard Stevens and Gordon Stout. Three Pulitzer Prize winners were brought together to compose three new works for the marimba. The resulting pieces were: Reflections on the Nature of Water by Jacob Druckman, Velocities by Joseph Schwantner, and Islands from Archipelago: Autumn Island by Roger Reynolds. A brief history of the classical concert marimba and the development of solo marimba literature is provided ...
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc4879/
1996 protocol to Convention on Prevention of Marine Pollution by Dumping of Wastes : message from the President of the United States transmitting 1996 protocol to the Convention on the Prevention of Marine Pollution by Dumping of Wastes and Other Matter (the "London Convention"), done in London on November 7, 1996 ; the protocol was signed by the United States on March 31, 2008 [i.e. 1998], and was entered into force on March 24, 2006
Date: 2007
Creator: United States. President (2001-2009 : Bush)
Description: This treaty strengthens protection of marine environments from dumping of waste.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc31108/
2008 DOT GOV Harvest Preserving Access
Date: October 21, 2008
Creator: Hartman, Cathy Nelson
Description: This presentation outlines the history, tool building, partner activities and future work for a collaborative project between the University of North Texas, the Library of Congress, the Internet Archive, the California Digital Library, and the U.S. Government Printing Office.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc28365/
2012 Presidential Primaries
Date: April 2012
Creator: Mondragon-Becker, Antonio
Description: This poster introduces the faculty lecture series UNT Speaks Out on the 2012 Presidential Primaries. This series features Dr. Tony Carey, assistant professor in the Department of Political Science, Dr. Matthew Eshbaugh-Soha, associate professor in the Department of Political Science, and Dr. Brian Lain, associate professor in the Department of Communications Studies and director of UNT's Debate Program.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc83784/
D. A. Kolb’s Theory of Experiential Learning: Implications for the Development of Music Theory Instructional Material
Date: August 2001
Creator: Lively, Michael
Description: This research project evaluates the effectiveness of specific music theory instructional strategies in terms of D. A. Kolb’s theory of experiential learning and Kolb’s typology of individual learning style. The project provides an original methodology for the adaptation of music theory instructional material to the individual learning style types described in Kolb’s typology. The study compares the relative effectiveness of two music theory instructional sequences, one of which is adapted for all of the learning style modalities described in Kolb’s typology, and the other adapted for only a limited number of Kolb’s learning style types. In order to compare the potential “learning outcomes” produced by these instructional sequences, a detailed study is proposed, in which computer based instruction (CBI) will deliver the instructional sequences to research participants and electronically record the participants’ responses. The current study demonstrates the effective aspects of the original methodology and suggests methods for the successful adaptation of music theory instructional material to individual student learning styles.
Contributing Partner: UNT Libraries
Permallink:digital.library.unt.edu/ark:/67531/metadc5813/