Enhancement by Human Chorionic Gonadotropin of Transformation of Chick Embryo Fibroblasts and Rat Kidney Cells Infected with Temperature-Sensitive and Wild Type Rous Sarcoma Viruses
Description:
Human chorionic gonodotropin (HCG) affected in various ways cell cultures infected with strains of Rous sarcoma virus (RSV). The cell cultures studied were chick embryo fibroblasts (CEF), normal rat kidney cells infected with temperature-sensitive mutant (LA31-NRK) and a wild type RSV (B77-NRK). HCG increased the rate of transformation and viral titer of CEF cells infected with RSV, but not B77-NRK. HCG increased significantly transformation rates of LA31-NRK, only if the temperature sensitive …
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Date:
August 1981
Creator:
Mitchell, Monte Mark