UNT Scholarly Works - 22 Matching Results

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Identification of Novel Antimicrobial Resistance Genes Using Machine Learning, Homology Modeling, and Molecular Docking

Description: Article claims antimicrobial resistance (AMR) threatens the healthcare system worldwide with the rise of emerging drug resistant infectious agents. To infer novel resistance genes, we used complete gene sets of several bacterial strains known to be susceptible or resistant to specific drugs and associated phenotypic information within a machine learning framework that enabled prioritizing genes potentially involved in resistance.
Date: October 23, 2022
Creator: Sunuwar, Janak & Azad, Rajeev K.
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Partner: UNT College of Science
open access

Analysis of transcribed sequences from young and mature zebrafish thrombocytes

Description: Article studying thrombocyte function and development in adult zebrafish. The authors performed single-cell RNA sequencing of the young and mature zebrafish thrombocytes and compared the two datasets for young and mature thrombocyte transcripts.
Date: March 23, 2022
Creator: Fallatah, Weam; De, Ronika; Burks, David J.; Azad, Rajeev K. & Jagadeeswaran, Pudur
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Partner: UNT College of Science
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In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions

Description: This article presents a study with the purpose to deliver a Notch Intracellular Domain (NICD)-encoded plasmid via poly(lactic-co-glycolic acid) (PLGA) nanoparticles and to investigate the toxic environmental side effects for an in vivo experiment. This research demonstrates that PLGA nanoparticle-mediated target delivery to upregulate Notch related genes can be a potential therapeutic approach with minimum toxic effects.
Date: February 23, 2022
Creator: Messerschmidt, Victoria L.; Chintapula, Uday; Bonetesta, Fabrizio; Laboy-Segarra, Samantha; Naderi, Amir; Nguyen, Kytai T. et al.
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Partner: UNT College of Science
open access

The EAR-motif of the Cys2/His2-type Zinc Finger Protein Zat7 Plays a Key Role in the Defense Response of Arabidopsis to Salinity Stress

Description: Article reporting that transgenic Arabidopsis plants constitutively expressing the Cys2/His2 zinc finger protein Zat7 have suppressed growth and are more tolerant to salinity stress. Findings demonstrate that the EAR-domain of Cys2/His2-type zinc finger proteins plays a key role in the defense response of Arabidopsis to abiotic stresses.
Date: March 23, 2007
Creator: Ciftci-Yilmaz, Sultan; Morsy, Mustafa R.; Song, Luhua; Coutu, Alicia; Krizek, Beth A.; Lewis, Michael W. et al.
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Partner: UNT College of Science
open access

Scaling of axial muscle architecture in juvenile Alligator mississippiensis reveals an enhanced performance capacity of accessory breathing mechanisms

Description: Article describing the anatomy of the trunk muscles, their properties that determine muscle performance (mass, length and physiological cross-sectional area [PCSA]) and investigating their scaling in juvenile Alligator mississippiensis spanning an order of magnitude in body mass (359 g–5.5 kg). Findings support existing anecdotal evidence that crocodilians shift their breathing mechanics as they increase in size.
Date: July 23, 2021
Creator: Rose, Kayleigh A. R.; Tickle, Peter G.; Elsey, Ruth M.; Sellers, William I.; Crossley, Dane A., II & Codd, Jonathan R.
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Partner: UNT College of Science
open access

Rapid embryonic accretion of docosahexaenoic acid (DHA) in the brain of an altricial bird with an aquatic-based maternal diet

Description: This article communicates the results of a study conducted on red-winged blackbirds where brain phospholipid composition during development was measured and diet was manipulated. The dietary study confirmed that nestling brains are sensitive to fatty acid supply. The findings of this article suggest that Red-winged blackbirds may be able to advance cognitive development relative to other altricial species owing to their aquatic maternal diet.
Date: July 23, 2018
Creator: Price, Edwin R.; Sirsat, Sarah K. G.; Sirsat, Tushar S.; Venables, Barney J. & Dzialowski, Edward M. (Edward Michael)
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Partner: UNT College of Science
open access

One thousand plant transcriptomes and the phylogenomics of green plants

Description: Article describes the results of the One Thousand Plant Transcriptomes Initiative's efforts to sequence the vegetative transcriptomes of 1,124 species that span the diversity of plants in a broad sense (Archaeplastida), including green plants (Viridiplantae), glaucophytes (Glaucophyta) and red algae (Rhodophyta).
Date: October 23, 2019
Creator: One Thousand Plant Transcriptomes Initiative
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Partner: UNT College of Science
open access

Altered expression of ionotropic L-Glutamate receptors in aged sensory neurons of Aplysia californica

Description: Article describes study in which mRNA expression of iGluR was quantified in two sensory neuron clusters of two cohorts of Aplysia californica (Aplysia) at both sexual maturity (~8 months) and advanced age (~12 months) in order to examine if changes in ionotropic L-Glu receptor (iGluR) transcription underlie reduced physiology8
Date: May 23, 2019
Creator: Greer, Justin B.; Mager, Edward M. & Fieber, Lynne A.
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Partner: UNT College of Science
open access

ARABIDOPSIS DEHISCENCE ZONE POLYGALACTURONASE 1 (ADPG1) releases latent defense signals in stems with reduced lignin content

Description: Article highlights the importance of pectin in cell wall integrity and the value of lignin modification as a tool to interrogate the informational content of plant cell walls.
Date: January 23, 2020
Creator: Gallego-Giraldo, Lina; Liu, Chang; Pose-Albacete, Sara; Pattathil, Sivakumar; Peralta, Angelo Gabriel; Young, Jenna et al.
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Partner: UNT College of Science
open access

Evaluation of a Chicken 600K SNP genotyping array in non-model species of grouse

Description: This article tested the cross-species application of the Affymetrix 600K Chicken SNP array in five species of North American prairie grouse (Centrocercus and Tympanuchus genera). This study study provided evidence for successful cross-species application of the chicken SNP array in grouse which diverged ca. 37 mya from the chicken lineage. As far as the authors are concerned, this is the first reported application of a SNP array in non-passerine birds, and it demonstrates the feasibility of usi… more
Date: April 23, 2019
Creator: Minias, Piotr; Dunn, Peter O.; Whittingham, Linda A.; Johnson, Jeff A. & Oyler-McCance, Sara
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Partner: UNT College of Science
open access

A chemical genetic screen uncovers a small molecule enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis

Description: This article demonstrates the feasibility of using an unbiased chemical genetic approach to identify new pharmacological tools for manipulating FAAH- and NAE-mediated physiological processes in plants.
Date: January 23, 2017
Creator: Khan, Bibi Rafeiza; Faure, Lionel; Chapman, Kent D. & Blancaflor, Elison B.
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Partner: UNT College of Arts and Sciences
open access

ROS Are Good

Description: This opinion article focuses on the possibility that ROS are beneficial to plants, supporting cellular proliferation, physiological function, and viability, and that maintaining a basal level of ROS in cells is essential for life.
Date: September 23, 2016
Creator: Mittler, Ron
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Partner: UNT College of Arts and Sciences
open access

Phenotypic developmental plasticity induced by preincubation egg storage in chicken embryos (Gallus gallus domesticus)

Description: This article investigates how preincubation egg storage conditions (temperature, duration, hypoxia, and hypercapnia) affects viability, body mass, and physiological variables and functions in day 15 chicken embryos.
Date: January 23, 2016
Creator: Branum, Sylvia R.; Tazawa, Hiroshi & Burggren, Warren W.
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Partner: UNT College of Arts and Sciences
open access

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Description: Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Date: May 23, 2013
Creator: Subramaniam, Aruljothi; Loo, Ser Yue; Rajendran, Peramaiyan; Manu, Kanjoormana Aryan; Perumal, Ekambaram; Li, Feng et al.
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Partner: UNT College of Arts and Sciences
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