Development of Biodegradable Nanocarriers Loaded with a Monoclonal Antibody
Description:
This article examines the feasibility of encapsulating monoclonal antibodies within poly(lactic-co-glycolic acid) (PLGA) nanoparticles using a water/oil/water double emulsion solvent evaporation technique. This method can be used to prepare protective polymeric nanoparticles for transporting functional antibodies to the cytoplasmic compartment of cancer cells. The author's studies achieved successful formulation of antibody loaded polymeric nanoparticles, thus indicating that a PLGA-based antib…
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Date:
February 12, 2015
Creator:
Gdowski, Andrew; Ranjan, Amalendu; Mukerjee, Anindita & Vishwanatha, Jamboor
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Partner:
UNT Health Science Center