Flanking Variation Influences Rates of Stutter in Simple Repeats
Description:
This article shows that rates of stutter can vary substantially depending on the flanking haplotype, and while there are cases where the LUS is a better predictor of stutter than the PAL, examples to the contrary are apparent in commonly assayed forensic markers. Further, flanking variation that is 7 bp from the repeat region can impact rates of stutter. These findings suggest that non-proximal effects, such as DNA secondary structure, may be impacting the rates of stutter in common forensic sh…
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Date:
November 17, 2017
Creator:
Woerner, August E.; King, Jonathan L. & Budowle, Bruce
Item Type:
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Partner:
UNT Health Science Center