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Center for Drug Evaluation and Research: Artificial Intelligence in Drug Manufacturing

Description: This report discusses FDA's consideration of the application of its risk-based regulatory framework to the use of AI technologies in drug manufacturing. The authors of the report ask the public to provide feedback after reading this report.
Date: February 28, 2023
Creator: United States. Food and Drug Administration.
Partner: UNT Libraries Government Documents Department
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Zirconium Hazards Research

Description: "The study of the sensitivity characteristics of Zr samples such as sponge, scrap, foil, and powder was continued. Of particular interest was the determination of the relative sensitivity of these materials to such stimuli as electrostatic discharge and an induced shock wave. The investigation of the zirconium-water reaction and zirconium-gas reactions at relatively low temperatures was continued."
Date: February 28, 1958
Creator: Herickes, J. A.; Richardson, P. A.; Weiss, M. & Geuerbterm, G.
Partner: UNT Libraries Government Documents Department
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Water Hammer Tests Loop Able Pwp Land Reactor, 1957

Description: "This report essentially substantiates the preliminary data reported ln WAPD-PWR-PMF-898. The Primary Coolant System of the Pressurized Water Reactor (PWR) at Shippingport, Pennsylvania, comprises four loops. Each of the loops has one pump to control the mass rate of water flow-. A series of tests were conducted on the cooling system of the PWR land reactor to determine the magnitude and duration of the water hammer pressure wave resulting from check valve closure. The water hammer pressure wav… more
Date: February 28, 1958
Creator: Brewer, G. A. & Wing, J. C.
Partner: UNT Libraries Government Documents Department
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Spectrographic Analysis of Normal Human Tissue from Miami, Florida

Description: All tissues included in this report were received from Miami, Florida and the majority are from Jackson memorial Hospital. They were collected, ashed and analyzed according to the methods described in ORNL-CF-57-2-2. The average value of the concentration for each element in a tissue is the average of the concentrations in only those samples of the tissue which contained the element. For example, if, of 25 lives analyzed, only 10 contained lead, the average for lead in liver is the average of t… more
Date: February 28, 1957
Creator: Tipton, I. H.; Cook, M. J.; Steiner, R. L.; Foland, J. M. & McDaniel, K. K.
Partner: UNT Libraries Government Documents Department
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Methods of Collection, Preparation and Spectrographic Analysis of Human Tissues

Description: To determine the maximum permissible concentration (MPC) of a radionuclide which may be ingested or inhaled with exceeding accepted levels of exposure tot he human body, it is necessary to know the average normal concentration of the natural element in the various tissues of the body. Any element may be ingested or inhaled as the element or as a compound. Although nearly all elements have been observed in living tissue, few quantitative observations had been made before 1950. Preliminary studie… more
Date: February 28, 1957
Creator: Tipton, I. H.; Cook, M. J.; Steiner, R. L.; Foland, J. M.; Fentress, S. D. & McDaniel, K. K.
Partner: UNT Libraries Government Documents Department
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Use of Hood Cells for Enclosing Low Level Radiation Processes

Description: A perspective drawing of typical hood cells arranged in series for an assembly line operation is presented. Advantages of this improved enclosure for low level radiation work are listed which recommend its use on new facilities in preference to more conventional designs.
Date: February 28, 1957
Creator: Moulthrop, H. A.
Partner: UNT Libraries Government Documents Department
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A Theory of Hyperfragments

Description: "Mesic decay of hyperfragments is discussed systematically on the basis of a previous model for hyperfragments. The general formalism for the two-body and three-body mesic decay was developed. The polarization-direction correlation and the angular correlation for the two-body and the three-body decays are discussed together with the decay probability. The formalism was developed so as to include the isotopic spin selection rule ( DELTA I = 1/2 and 3/2) for the mesic decays. The theory was appli… more
Date: February 28, 1961
Creator: Iwao, Syurei
Partner: UNT Libraries Government Documents Department
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The Heavy-Water Homogeneous Pile: a Review of Chemical Researches and Problems

Description: Technical Report: A generalized review of the chemical problems and researches related principally to the heavy water homogeneous pile is presented herewith. The report covers researches performed principally by the Columbia Group who initiated the study. This report contains a chronological outline of the development, a discussion of some special topics whose significance is paramount in any slurry pile discussion, and finally an outline of important research problems remaining, roughly grad… more
Date: February 28, 1944
Creator: Hiskey, C. F. & Eidinoff, Maxwell Leigh, 1915-
Partner: UNT Libraries Government Documents Department
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Hydrogeochemical and Stream Sediment Reconnaissance Basic Data for Scottsbluff NTMS Quadrangle, Nebraska and Colorado

Description: "Results of a reconnaissance geochemical survey of the Scottsbluff Quadrangle are reported. Field and laboratory data are presented for 567 groundwater and 402 stream sediment samples. statistical distributions and symbol plots for uranium and possible uranium-related variables are enclosed. A generalized geologic map and a producing horizon map for the survey area are provided. Pertinent geologic factors that may be of significance in evaluating the potential for uranium mineralization are bri… more
Date: February 28, 1981
Creator: National Uranium Resource Evaluation Program
Location: See Bounding Coordinates
Partner: UNT Libraries Government Documents Department
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Medical and Health Physics Quarterly Report: October, November, and December 1951

Description: The document provides reports on medical and health physics, particularly on the biological studies of radiation effects, the metabolic properties of various materials, radiation chemistry, health chemistry, and health physics.
Date: February 28, 1952
Creator: Lawrence Radiation Laboratory
Partner: UNT Libraries Government Documents Department
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Fission Product Activity in SM-1 Core I Primary System and Surface Contamination on SM-1 Type Fuel Elements. Task XVIII, Phases 2 and 3

Description: Abstract; The fission product data obtained during SM-1 Core I operation (June 1957 - May 1960) is reviewed briefly and interpreted. Evidence is presented to indicate that a fuel element defect was responsible for the high fission product activity level observed in the primary coolant. Relative escape coefficients are calculated and the defect size estimated. Anticipated fission product levels during SM-1 Core II and SM-1A Core I operation are estimated from alpha surface contamination data o… more
Date: February 28, 1961
Creator: Hasse, Robert A. & Zegger, John L.
Partner: UNT Libraries Government Documents Department
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Hazards Report for SM-1 Core Temperature and Flow Instrumentation (Task XIV) Covering Special Test Procedures.

Description: Abstract: Test procedures for special tests involving in-core SM-1 temperature and flow instrumentation are described (Task XIV Package Tests). These tests involve in-core steady state flow and temperature measurements, loss of flow transients, load transients, reduced primary system pressure operations and reduced element flow. The thermal and hydraulic conditions prevailing in these tests, including steady state and transient burnout rations, are developed. The effects of reduced system pres… more
Date: February 28, 1962
Creator: Bradley, P. L. & Coombe, J. R.
Partner: UNT Libraries Government Documents Department
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BWR Reference Design for PL-3

Description: Abstract: The natural circulation, direct cycle, boiling water reactor reference design presented in this technical report is the alternate to the preferred preliminary design developed under Phase I of the PL-3 contract. The report presents plant design criteria, summary of plant selection, plant description, reactor and primary system description, thermal and hydraulic analysis, nuclear analysis, control and instrumentation description, shielding description, auxiliary systems, power plant eq… more
Date: February 28, 1962
Creator: Humphries, G. E.
Partner: UNT Libraries Government Documents Department
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PWR Preliminary Design for PL-3

Description: Abstract: The pressurized water reactor preliminary design presented in this volume is the preferred design developed under Phase I of the PL-3 contact. This technical report presents plant design criteria, summary of plant selection, plant description, reactor and primary system description, thermal and hydraulic analysis, nuclear analysis, control and instrumentation description, shielding description, auxiliary systems, power plant equipment, waste disposal, buildings and tunnels, services, … more
Date: February 28, 1962
Creator: Humphries, G. E.
Partner: UNT Libraries Government Documents Department
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Intermediate Heat Exchanger Preliminary Design. Vol. 1, IHX Preliminary Design

Description: Preface: The intermediate heat exchanger is designed for operation in a nuclear power plant using liquid sodium as the primary and secondary coolant. Since the primary fluid coming from the reactor is radioactive, the purpose of the IHX is to transfer heat to a nonradioactive fluid which then goes to a steam generator. Because of this activity the until will be enclosed in a concrete pit and will not be accessible during periods of operation. Immediately after shut down it will be necessary … more
Date: February 28, 1959
Creator: Alco Products (Firm)
Partner: UNT Libraries Government Documents Department
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Report of Stonewall Democrats of Texas Audit Committee

Description: Report of Stonewall Democrats of Texas Audit Committee covering financial policies and procedures, banking and compliance with Texas Ethics Commission's reporting requirements for General Political Action Committees.
Date: February 28, 2009
Partner: UNT Libraries Special Collections
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Texas Stonewall Democratic Caucus Executive Board Meeting

Description: Minutes of members meeting of the Texas Stonewall Democratic Caucus on February 28, 2009. A breakdown of various topics discussed including other committee reports. Photocopy of Texas Stonewall Democratic Caucus custom summary report from January 1 through February 26, 2009. Photocopy of Texas Stonewall Democratic Caucus transaction detail by account of $858.44 from January 1 through February 26, 2009. Photocopy of Texas Stonewall Democratic Caucus custom summary report from July through Decemb… more
Date: February 28, 2009
Partner: UNT Libraries Special Collections
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LAPACK Working Note 9: A test matrix generation suite

Description: We discuss the design and implementation of a suite of test matrix generators for testing linear algebra software. These routines generate random matrices with certain properties which are useful for testing linear equation solving, least squares, and eigendecomposition software. These properites include the spectrum, symmetry, bandwidth, norm, sparsity, conditioning (with respect to inversion or for the eigenproblem), type (real or complex), and storage scheme (dense, packed or banded).
Date: February 28, 1989
Creator: Demmel, J. & McKenney, A. (New York Univ., NY (United States). Courant Institute)
Partner: UNT Libraries Government Documents Department
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Characterizing cinder rock with the scanning electron microscope. [From in-situ retorting]

Description: Friable cinder rock was examined by scanning electron microscopy and energy dispersive x-ray analysis (SEM/ED). The technique consisted of impregnating the rock with epoxy resin and then locating porosity sites by the presence of epoxy. The resin was identified in the sample by correlating beam damage and elemental analysis by x-ray fluorescence (ED) with a characteristic phase in the SEM image. Analyses of this type should be useful in interpreting experiments designed to simulate in situ reto… more
Date: February 28, 1977
Creator: Casey, A. W.
Partner: UNT Libraries Government Documents Department
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Basal Ottawa Limestone, Chattanooga Shale, Floyd Shale, Porters Creek Clay, and Yazoo Clay in parts of Alabama, Mississippi and Tennessee as potential host rocks for underground emplacement of waste

Description: Impermeable rock units, preferably at least 500 feet thick and lying 1000 to 3000 feet below land surface, were sought in the region consisting roughly of the western /sup 3///sub 5/ths of Tennessee and the northern /sup 3///sub 5/ths of Alabama and Mississippi. All rock sequences, Cambrian through Eocene, were examined in varying detail, except the Cretaceous Selma Chalk and except the diapiric salt. These rocks were studied for their relative impermeable homogeneity, their continuity, their b… more
Date: February 28, 1976
Creator: Mellen, F. F.
Partner: UNT Libraries Government Documents Department
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An Evaluation of DOE-EM Public Participation Programs

Description: This report evaluates the scope and effectiveness of the public participation pr ograms, including Site-Specific Advisory Boards (SSABs), at seven U.S. Departmen t of Energy (DOE) sites: Fernald, Hanford, Los Alamos, Nevada, Oak Ridge, Paduc ah, and Savannah River. The primary purpose of the study is to assist both DOE Field and Headquarters managers in reviewing and understanding lessons learned o ver the past decade concerning public participation programs administered by the DOE Office of En… more
Date: February 28, 2003
Creator: Bradbury, Judith A.; Branch, Kristi M. & Malone, Elizabeth L.
Partner: UNT Libraries Government Documents Department
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