Search Results

open access

Dual activity of anthocyanidin reductase supports the dominant plant proanthocyanidin extension unit pathway

Description: This article presents research on genetic and biochemical analyses that shows ANR has dual activity and is involved not only in the production of (−)-epicatechin starter units but also in the formation of 2,3-cis-leucocyanidin to serve as (−)-epicatechin extension units. The results find that differences in the product specificities of ANRs account for the presence/absence of PA polymerization and the compositions of PAs across plant species
Date: May 14, 2021
Creator: Jun, Ji Hyung; Lu, Nan; Docampo-Palacios, Maite; Wang, Xiaoqiang & Dixon, Richard A.
Partner: UNT College of Science
open access

Elucidating the multifunctional role of the cell wall components in the maize exploitation

Description: Article on the composition of the four cell wall fractions in diverse maize genotypes and to understand how this composition influences the resistance to pests, ethanol capacity and digestibility. Results evidence that there is no maize cell wall ideotype among the tested for optimal performance for various uses, and maize plants should be specifically bred for each particular application.
Date: June 2, 2021
Creator: López-Malvar, Ana; Malvar, Rosa Ana; Souto, Xose Carlos; Gomez, Leonardo Dario; Simister, Rachael; Encina, Antonio et al.
Partner: UNT College of Science
open access

Evaluating spatial patterns of seasonal ozone exposure and incidence of respiratory emergency room visits in Dallas-Fort Worth

Description: This article examines the relationships between spatial patterns of long-term ozone exposure and respiratory illness within Dallas-Fort Worth to better understand impacts on health outcomes.
Date: April 13, 2021
Creator: Northeim, Kari; Marks, Constant & Tiwari, Chetan
Partner: University of North Texas
open access

The impact of multifactorial stress combination on plant growth and survival

Description: Article studying seedlings of wild-type and different mutants of Arabidopsis thaliana plants subjected to a multifactorial stress combination of six different stresses, each applied at a low level, and their survival, physiological and molecular responses. Findings reveal that further polluting our environment could result in higher complexities of multifactorial stress combinations that in turn could drive a critical decline in plant growth and survival.
Date: January 26, 2021
Creator: Zandalinas, Sandra I.; Sengupta, Soham; Fritschi, Felix B.; Azad, Rajeev K.; Nechushtai, Rachel & Mittler, Ron
Partner: UNT College of Science
open access

Arabidopsis thaliana EARLY RESPONSIVE TO DEHYDRATION 7 Localizes to Lipid Droplets via Its Senescence Domain

Description: This article includes a proteomics analysis of Lipid Droplets (LDs) isolated from drought-stressed Arabidopsis leaves and identifying EARLY RESPONSIVE TO DEHYDRATION 7 (ERD7) as a putative LD protein. Observations provide new insight to ERD7 and the SD-containing family of proteins in plants and suggest that ERD7 may be involved in functional aspects of plant stress response that also include localization to the LD surface.
Date: April 14, 2021
Creator: Doner, Nathan M.; Seay, Damien C.; Mehling, Marina; Sun, Siqi; Gidda, Satinder K.; Schmitt, Kerstin et al.
Partner: UNT College of Science
open access

CRISPR/Cas9-Induced fad2 and rod1 Mutations Stacked With fae1 Confer High Oleic Acid Seed Oil in Pennycress (Thlaspi arvense L.)

Description: Article utilizing Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology to produce knockout mutations in the FATTY ACID DESATURASE2 (FAD2) and REDUCED OLEATE DESATURATION1 (ROD1) genes to increase oleic acid content in Pennycress (Thlaspi arvense L.). Results suggest that combinatorial knockout of ROD1 and FAE1 may be a viable route to commercially increase oleic acid content in pennycress seed oil whereas mutations in FAD2 will likely require at least partial function to avoid fitness trade-offs.
Date: April 22, 2021
Creator: Jarvis, Brice A.; Romsdahl, Trevor B.; McGinn, Michaela G.; Nazarenus, Tara J.; Cahoon, Edgar B.; Chapman, Kent Dean et al.
Partner: UNT College of Science
open access

Frontiers in Aquatic Physiology – grand challenge

Description: Opinion article covering grand challenges to aquatic physiology based on the five "grand challenges in organismal biology" proposed by Schwenk et al. (2007). This article also provides a list of specific examples of emerging areas of research interest in aquatic physiology.
Date: May 18, 2010
Creator: Evans, David H.; Axelsson, Michael; Beltz, Barbara; Burggren, Warren W.; Castellini, Michael; Clements, Kendall D. et al.
Partner: UNT College of Science
open access

Dietary Exposure to Low Levels of Crude Oil Affects Physiological and Morphological Phenotype in Adults and Their Eggs and Hatchlings of the King Quail (Coturnix chinensis)

Description: Article studying the king quail as an animal model to determine if chronic dietary exposure to crude oil in a parental population affects morpho-physiological phenotypic variables in their immediate offspring generation.
Date: April 9, 2021
Creator: Bautista, Naim M.; Do Amaral-Silva, Lara; Dzialowski, Edward M. (Edward Michael) & Burggren, Warren W.
Partner: UNT College of Science
open access

Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina

Description: This article explores swimming stamina in fish. Mature adult zebrafish (Danio rerio) were subjected to a swimming performance test and then bred within performance groups to discover if enhanced swimming stamina in offspring appears only in juveniles/adults, or if these traits appear as early as larvae.
Date: February 24, 2012
Creator: Burggren, Warren W. & Gore, Matthew
Partner: UNT College of Science
open access

Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals

Description: Article evaluating the response to the pharmacological compounds Fluoxetine, Muscimol, and Verapamil in primary neuronal cultures. Final conclusions are drawn that MEA technology has a potential for standard in vitro neurotoxicity/neuropharmacology evaluation.
Date: April 27, 2011
Creator: Novellino, A.; Scelfo, Bibiana; Palosaari, T.; Price, A.; Sobanski, Tomasz; Shafer, T.J. et al.
Partner: UNT College of Science
open access

Targeting hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase for lignin modification in Brachypodium distachyon

Description: This article conducts a study to evaluate the utility of Hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT) as a target for lignin modification in a species with an “incomplete” shikimate shunt. Results imply that this gene is a preferred target for biotechnological improvement of grasses for bioprocessing.
Date: February 27, 2021
Creator: Serrani-Yarce, Juan Carlos; Escamilla-Treviño, Luis; Barros, Jaime; Gallego-Giraldo, Lina; Pu, Yunqiao; Ragauskas, Arthur J. (Arthur Jonas), 1957- et al.
Partner: UNT College of Science
open access

Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network

Description: Article discovering a mechanism for how sphingolipids mediate phosphoinositide homeostasis at the TGN in plant cells. The data presented identifies a mode of action of sphingolipids in lipid interplay at the TGN during protein sorting.
Date: July 13, 2021
Creator: Ito, Yoko; Esnay, Nicolas; Pierre Platre, Matthieu; Wattelet-Boyer, Valérie; Noack, Lise C.; Fougère, Louise et al.
Partner: UNT College of Science
open access

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Description: Article identifying novel epigenetic regulators for tfpia and exploiting this information to discover a drug that enhances tfpia mRNA levels and prolongation of TTO. This discovery provides the basis for testing whether UNC6852 could be used as an antithrombotic drug.
Date: July 27, 2021
Creator: Raman, Revathi; Fallatah, Weam; Al Qaryoute, Ayah; Dhinoja, Sanchi & Jagadeeswaran, Pudur
Partner: UNT College of Science
open access

Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Description: Article investigating if the exposure to diesel exhaust particles (DEP) can alter commensal lung microbiota, thereby promoting alterations in the lung’s immune and inflammatory responses. This article also explores if diet contributes to the alteration of the commensal lung microbiome.
Date: January 8, 2021
Creator: Daniel, Sarah; Phillippi, Danielle; Schneider, Leah J.; Nguyen, Kayla N.; Mirpuri, Julie & Lund, Amie K.
Partner: UNT College of Science
open access

Developmental thyroid disruption causes long-term impacts on immune cell function and transcriptional responses to pathogen in a small fish model

Description: This article explores the connection between thyroid hormones (THs) and immune systems in fish. This article is noteworthy as disruption of the thyroid system during development, which can occur in response to chemicals present in the environment, may have lasting effects on immune function in adulthood for fish.
Date: July 14, 2021
Creator: Thornton Hampton, Leah M.; Finch, Miranda G.; Martyniuk, Christopher J.; Venables, Barney J. & Sellin Jeffries, Marlo K.
Partner: UNT College of Science
open access

Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

Description: This article explores DNA methylation's role in the regulation of gene expression in reptiles. Results show that embryonic hypoxia programs DNA methylation and gene expression patterns and that these changes are associated with enhanced cardiac anoxia tolerance in snapping turtles later in life.
Date: September 6, 2021
Creator: Ruhr, Ilan; Bierstedt, Jacob; Rhen, Turk; Debojyoti, Das; Singh, Sunil Kumar; Miller, Solielle et al.
Partner: UNT College of Science
open access

A rapid thioacidolysis method for biomass lignin composition and tricin analysis

Description: This article developed a modified, rapid higher throughput thioacidolysis method to analyze both lignin monomeric composition and tricin content in the lignin polymer. The results demonstrate that the modified method can be used for rapid, high-throughput, and reliable lignin composition and tricin content analyses for screening transgenic plants for cell wall modifications or in large-scale genome-wide association studies (GWAS).
Date: January 11, 2021
Creator: Chen, Fang; Zhuo, Chunliu; Xiao, Xirong; Pendergast, Thomas H. & Devos, Katrien M.
Partner: UNT College of Science
open access

A gene-editing/complementation strategy for tissue-specific lignin reduction while preserving biomass yield

Description: This article develops a method, using a single DNA construct that uses CRISPR–Cas9 gene editing to knock-out expression of an endogenous gene of lignin monomer biosynthesis while at the same time expressing a modified version of the gene’s open reading frame that escapes cutting by the Cas9 system and complements the introduced mutation in a tissue-specific manner. This method is applicable to any plant species in which transformation and gene editing are feasible and validated vessel-specific promoters are available.
Date: September 3, 2021
Creator: Yu, Hasi; Liu, Chang & Dixon, Richard A.
Partner: UNT College of Science
open access

The accessory role of the diaphragmaticus muscle in lung ventilation in the estuarine crocodile Crocodylus porosus

Description: This article explores lung ventilation in crocodilians through direct measurements of ventilation, metabolic rate, and arterial blood gases of juvenile estuarine crocodiles in varying conditions. The results suggest that, in C. porosus, costal ventilation alone is able to support metabolic demands at rest, and the diaphragmaticus is largely an accessory muscle used at times of elevated metabolic demand.
Date: November 17, 2011
Creator: Munns, Suzanne L.; Owerkowicz, Tomasz; Andrewartha, Sarah J. & Frappell, Peter B.
Partner: UNT College of Science
open access

In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline

Description: This article measures the cardiac performance of Newfoundland Atlantic cod (Gadus morhua). The results: (1) show that maximum performance of the isolated cod heart is not compromised by exposure to cold temperatures; and (2) support data from other studies, which show that, in contrast to salmonids, cod cardiac performance/myocardial contractility is not dependent upon humoral adrenergic stimulation.
Date: November 15, 2012
Creator: Lurman, Glenn J. & Petersen, L. H.
Partner: UNT College of Science
open access

Pulmonary compliance and lung volume varies with ecomorphology in anuran amphibians: implications for ventilatory-assisted lymph flux

Description: This article examining the correlation between pulmonary compliance, lung volume, and lymph flux rates in anurans. The findings of this article suggest that lymph mobilization capacity may explain some of the variation in pulmonary compliance and lung volume in anurans.
Date: October 1, 2011
Creator: Hedrick, Michael; Hillman, Stanley S.; Drewes, Robert C. & Withers, Philip C.
Partner: UNT College of Science
open access

Childhood Asthma and Smoking: Moderating Effect of Preterm Status and Birth Weight

Description: Article exploring the association between second-hand smoke exposure, asthma, and asthma severity in children ages 6-17 as well as the effect of birth weight and prematurity (BWP) on parental smoking and asthma. Results indicate that focused asthma interventions in children should inquire about BWP status as well as parental smoking and household smoke exposure to reduce asthma morbidity and mortality.
Date: April 17, 2021
Creator: Ogbu, Chukwuemeka E.; Ogbu, Stella C.; Khadka, Dibya & Kirby, Russell S.
Partner: UNT College of Science
open access

Constraints-based stoichiometric analysis of hypoxic stress on steroidogenesis in fathead minnows, Pimephales promelas

Description: This article presents a study in which an in silico genome-scale metabolic model of steroidogenesis is used to investigate the effects of hypoxic stress on steroid hormone productions in fish. This article introduces a powerful model for pathway analysis that can lend insights on the effects of various stressor scenarios on metabolic functions.
Date: May 15, 2012
Creator: Hala, David; Petersen, Lene H.; Martinovic, Dalma & Huggett, Duane B.
Partner: UNT Institute of Applied Sciences
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