Search Results

Streptomyces bacteriophages putative Cas4 protein modeling

Description: Data collected as part of Sreemoye Nath's PhD dissertation, Exploring Microbial Systems: Carbon Dioxide Effect on Methanotrophs and CRISPR Systems in Streptomyces Bacteriophages. Chapter four explored the putative structure of the Cas4 protein. This is the modeling data for the protein structure.
Date: February 21, 2026
Creator: Nath, Sreemoye
Partner: UNT College of Science
open access

Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition

Description: Article investigates the role of the transmembrane protein TMEM242 in hemostasis using zebrafish thrombocytes and gene knockdown experiments. The findings show that TMEM242 depletion increases bleeding and reactive oxygen species levels, disrupts coagulation and fibrin formation, and alters clotting factor gene expression, suggesting a mechanism involving impaired ATP synthase, ROS signaling, and upregulation of SIRT6 and NRF2.
Date: January 24, 2025
Creator: Deebani, Afnan; Mary, Jabila; Dhinoja, Sanchi; Al Qaryoute, Ayah; Fallatah, Weam & Jagadeeswaran, Pudur
Partner: UNT College of Science
open access

RareNet: a deep learning model for rare cancer diagnosis

Description: Article presents RareNet, a transfer‑learning deep‑learning model designed to improve early detection of rare cancers using DNA methylation data. Demonstrating an F1 score of ~96%, RareNet outperforms several traditional machine‑learning approaches and highlights the potential of AI‑driven methods for rare cancer classification.
Date: July 2, 2025
Creator: Shao, Danyang; Addagudi, Sohan; Cowles, Joseph; Jain, Arnav; D'Souza, Lauren; Gore, Steven et al.
Partner: UNT College of Science
open access

Increased stability of a subtropic bamboo forest soil bacterial communities through integration of water and fertilizer management compared to conventional management

Description: Article investigates how integrating water and fertilizer management (IWF) influences soil properties and bacterial communities in bamboo forests compared to conventional management practices. Using high‑throughput sequencing, the study shows that IWF improves soil pH, nutrient status, and bacterial diversity while restoring beneficial microbial communities diminished under conventional methods. The findings demonstrate that IWF can effectively prevent soil acidification and support healthier s… more
Date: November 13, 2024
Creator: Li, Yi; Compson, Zacchaeus Greg; Kuang, Xiaobao; Lin, Yu-Fen; Song, Qingni; Liu, Chang-Jun et al.
Partner: UNT College of Science
open access

Celebrating 360 years of Philosophical Transactions

Description: Article marks the 360th anniversary of Philosophical Transactions and launches a year‑long celebration of the Royal Society’s publishing legacy. Reflecting on the journal’s remarkable longevity and its foundational role in the history of science, the piece highlights how its original mission, - sharing reliable knowledge for the benefit of humanity, - continues to guide scientific publishing today. The anniversary underscores both the journal’s historical impact and its ongoing commitment to ad… more
Date: January 9, 2025
Creator: Dixon, R. A. & Eaton, Helen
Partner: UNT College of Science
open access

Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum

Description: Article investigates early plant responses to Fusarium graminearum infection by profiling global changes in microRNA (miRNA) expression within the Arabidopsis–Fusarium pathosystem and identifies both known stress‑related and evolutionarily young miRNAs that shift significantly before visible symptoms appear, revealing candidates that may play causal roles in defense signaling and offering potential pathways for developing crops with enhanced fungal resistance.
Date: February 6, 2025
Creator: Ferreira, Savio S.; Pandey, Suman; Hemminger, Jesseca; Bozdag, Serdar & Antunes, Mauricio S.
Partner: UNT College of Engineering
open access

Revealing pathogenesis-associated metabolites in Histoplasma capsulatum through comprehensive metabolic profiling

Description: Article investigates the metabolic adaptations of Histoplasma capsulatum during macrophage infection by comparing metabolomes of yeasts grown on distinct carbon sources with those extracted from host phagosomes. The study reveals unique metabolic signatures, including altered amino acid, lipid, and sugar profiles, secretion of mannitol and anthranilates, and reliance on leucine and cysteine/cystine during intracellular growth, highlighting metabolites that may serve as targets for future histop… more
Date: February 27, 2025
Creator: Heckart, Adrian; Cocuron, Jean-Christophe; Ray, Stephanie C.; Rappleye, Chad A. & Alonso, Ana Paula
Partner: UNT College of Science
open access

Targeted modulation of pennycress lipid droplet proteins impacts droplet morphology and seed oil content

Description: Article identifies key lipid‑droplet biogenesis proteins in pennycress and demonstrates that the LDIP protein can functionally complement the Arabidopsis ldip mutant, highlighting strong conservation of lipid‑storage mechanisms across Brassicas. Article further shows that pennycress ldip loss‑of‑function mutants accumulate more seed oil without growth penalties, suggesting LDIP and related factors as promising targets for enhancing oil yields in biofuel crops.
Date: October 28, 2024
Creator: Guzha, Athanas; Gautam, Barsanti; Marchiafava, Damiano; Sagun, Julius Ver; Garcia, Tatiana; Jarvis, Brice A. et al.
Partner: UNT College of Science
open access

A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis

Description: Article investigates the role of the plastidial transporter GPT2 in lignin biosynthesis, showing that GPT2 overexpression reduces lignin content by decreasing both guaiacyl and syringyl monolignol pools. Article suggests that GPT2 helps balance metabolic flux between lignin formation and light‑protective phenylpropanoid derivatives, revealing a transcriptional link between GPT2 and HCT expression.
Date: May 16, 2025
Creator: Raju, Aditi Subramani; Sahu, Abira; Zhuo, Chunliu; Versaw, Wayne K. & Dixon, R. A.
Partner: UNT College of Science
open access

Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosis

Description: Article reveals that systemic inflammation drives muscle stem‑cell aging by reducing H4K20 monomethylation, disrupting quiescence, and inducing ferroptosis through Kmt5a downregulation and epigenetic silencing of anti‑ferroptosis genes. Article further shows that long‑term inhibition of inflammation prevents ferroptosis, preserves MuSC populations, and enhances muscle regeneration, identifying an epigenetic switch linking chronic inflammation to stem‑cell decline and age‑related muscle degenera… more
Date: June 30, 2025
Creator: Blanc, Roméo S.; Shah, Nidhi; Hachmer, Sarah; Salama, Noah A. S.; Meng, Fanju W.; Mousaei, Alireza et al.
Partner: UNT College of Science
open access

Bryophytes hold a larger gene family space than vascular plants

Description: Article reveals that bryophytes possess far greater gene‑family diversity than vascular plants, as shown through a super‑pangenome analysis incorporating 123 newly sequenced genomes, uncovering extensive new gene formation and continuous horizontal gene transfer from microbes. Article demonstrates that this rich and lineage‑specific genetic toolkit, including unique immune receptors, likely enabled bryophytes to thrive across diverse and extreme habitats, offering valuable insights into alterna… more
Date: September 22, 2025
Creator: Dong, Shanshan; Wang, Sibo; Li, Linzhou; Yu, Jin; Zhang, Yongxia; Xue, Jia-Yu et al.
Partner: University of North Texas
open access

LIPID DROPLET PROTEIN OF SEEDS is involved in the control of lipid droplet size in Arabidopsis seeds and seedlings

Description: Article identifies LIPID DROPLET PROTEIN OF SEEDS (LDPS) as a seed‑specific, low‑abundance lipid‑droplet protein whose amphipathic α‑helix/proline‑hairpin motif targets LDs and whose separate interaction domain binds OLEOSIN 1. Article demonstrates that LDPS regulates LD size, seed oil content, and LD–LD fusion in Arabidopsis, functioning in opposition and cooperation with OLEO1 to control LD morphology during seed development and postgerminative growth.
Date: May 15, 2025
Creator: Doner, Nathan M.; Clews, Alyssa C.; Nicolas Esnay; Whitehead, Payton S.; Wang, You; Romsdahl, Trevor B. et al.
Partner: UNT College of Science
open access

Enhanced Antioxidant Activity and Secondary Metabolite Production in Tartary Buckwheat under Polyethylene Glycol (PEG)-Induced Drought Stress during Germination

Description: Article investigates the effects of polyethylene‑glycol‑induced drought stress on seed germination, physiological traits, and biochemical responses across 14 Tartary buckwheat genotypes. Article shows that drought‑tolerant genotypes—especially XiNong 9943—exhibit markedly elevated antioxidant enzyme activities and secondary metabolite accumulation under severe stress, validating the stress tolerance index and identifying XiNong 9943 as a strong candidate for future drought‑resilient breeding pr… more
Date: March 18, 2024
Creator: Hossain, Md. Shakhawat; Li, Jing; Wang, Chenyang; Monshi, Fakhrul Islam; Tabassum, Rehenuma; Islam, Md Ashraful et al.
Partner: UNT College of Science
open access

Pioglitazone with SGLT2 inhibitors or GLP-1 receptor agonists in patients with type 2 diabetes and non-alcoholic fatty liver disease: could the combinations of an old friend with new players yield better outcomes?

Description: Article examines the complex relationship between type 2 diabetes and non-alcoholic fatty liver disease (NAFLD), emphasizing insulin resistance as a key driver and the need for combination therapies targeting multiple pathways. It highlights the therapeutic potential of pioglitazone, GLP-1 receptor agonists, and SGLT2 inhibitors, as well as their combined use, in improving metabolic, cardiovascular, and liver-related outcomes.
Date: March 14, 2025
Creator: Papaetis, Georgios S.; Picolos, Michalis K. & Sacharidou, Anastasia
Partner: UNT College of Science

Chronic Development in Hypoxia Alters Femoral Artery and Vein Contractility in Juvenile Alligators (Alligator mississippiensis)

Description: This poster researches chronic development in hypoxia alters femoral artery and vein contractility in juvenile alligators (Alligator mississippiensis). It was presented at UNT's University Research Day event on October 2, 2025 in Denton, Texas.
Date: October 2, 2025
Creator: Rippamonti, Jessica; Williams, Steven; Crossley, Dane A., II & Dzialowski, Edward M. (Edward Michael)
Partner: University of North Texas

An Assessment of Oxidative Stress in Hyalella azteca Using Mass Spectrometry-Based Proteomics

Description: This poster analyzes an oxidative Stress in Hyalella azteca using mass spectrometry-based proteomics. It was presented at UNT's University Research Day event on October 2, 2025 in Denton, Texas.
Date: October 2, 2025
Creator: Tavva, Saharsh; Repala, West; Bada, Prathyum; DePoy, Carter; Prokai, Marcel L. & Shulaev, Vladimir
Partner: University of North Texas

Genetic capture-mark-recapture: a viable, non-invasive method for estimating wild turkey (Meleagris gallopavo) abundance in Texas

Description: This poster studies geneticcapture-mark-recapture: a viable, non-invasive method for estimating wild turkey (Meleagris gallopavo) abundance in Texas. It was presented at UNT's University Research Day event on October 2, 2025 in Denton, Texas.
Date: October 2, 2025
Creator: Molina, Clarissa & Gregory, Andrew
Partner: University of North Texas

HYDROLOGIC, METABOLIC, AND HUMAN EFFECTS ON STREAM DISSOLVED ORGANIC MATTER COMPOSITION IN A RAPIDLY URBANIZING ALPINE WATERSHED

Description: This poster investigates how hydrologic variability, stream metabolism, and human activities influence the composition of dissolved organic matter (DOM) in alpine watersheds undergoing rapid urbanization. It was presented at UNT's University Research Day event on October 2, 2025 in Denton, Texas.
Date: October 2, 2025
Creator: Mahawaththa, Ishani; Storb, Meryl B.; Payn, Robert A.; Junker, James R. & D’Andrilli, Juliana
Partner: University of North Texas

Too Green, Too Sparse, Just Right: The Goldilocks Zone of Vegetation for Harris’s Hawk Nesting Productivity

Description: This poster explores the Goldilocks zone of vegetation for Harris’s hawk nesting productivity. It was presented at UNT's University Research Day event on October 2, 2025 in Denton, Texas.
Date: October 2, 2025
Creator: Kent, Alexis; Poplin, Brooke; Bednarz, James C. & Gibbons, Andrea
Partner: University of North Texas
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