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open access

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

Description: Article investigates whether thymoquinone (TQ), a bioactive constituent of black seed oil, could suppress the proliferation and induce chemosensitization in human myeloma cells and xenograft mouse model. Overall, the results demonstrate that TQ can enhance the anticancer activity of bortezomib in vitro and in vivo and may have a substantial potential in the treatment of MM.
Date: December 18, 2013
Creator: Siveen, Kodappully Sivaraman; Mustafa, Nurulhuda; Li, Feng; Kannaiyan, Radhamani; Ahn, Kwang Seok; Kumar, Alan Prem et al.
Partner: UNT College of Arts and Sciences
open access

Arabidopsis Thaliana--Myzus Persicae Interaction: Shaping the Understanding of Plant Defense Against Phloem-Feeding Aphids

Description: This review article summarizes recent studies that have exploited the compatible interaction between Arabidopsis and the green peach aphid (GPA) to understand the molecular and physiological mechanisms utilized by plants to control aphid infestation, as well as genes and mechanisms that contribute to susceptibility.
Date: July 1, 2013
Creator: Louis, Joe & Shah, Jyoti
Partner: UNT College of Arts and Sciences
open access

Metabolic engineering of raffinose-family oligosaccharides in the phloem reveals alterations in carbon partitioning and enhances resistance to green peach aphid

Description: This article discusses the use of metabolic engineering to generate raffinose-family oligosaccharides (RFOs) at the inception of the translocation stream of Arabidopsis thaliana, which loads from the apoplasm and transports predominantly sucrose, and the fate of the sugars through the plant determined.
Date: July 19, 2013
Creator: Cao, Te; Lahiri, Ipsita; Singh, Vijay; Louis, Joe; Shah, Jyoti & Ayre, Brian G.
Partner: UNT College of Arts and Sciences
open access

Long-distance communication and signal amplication in systemic acquired resistance

Description: This review article summarizes the involvement and interaction between long-distance systemic acquired resistance (SAR) signals and details the recently discovered role of lysine catabolite pipecolic acid (Pip) in defense amplification and priming that allows plants to acquire immunity at the systemic level.
Date: February 22, 2013
Creator: Shah, Jyoti & Zeier, Jürgen
Partner: UNT College of Arts and Sciences
open access

Evolutionary implications of the distribution and variation of the skeletal muscles of the anuran lymphatic system

Description: This article defines character states and describes variation of these putative lymphatic skeletal muscles: the M. cutaneus pectoris, M. cutaneus dorsi, M. piriformis, M. sphincter ani cloacalis, and the complex of the M. gracilis minor/M. abdominal crenator.
Date: April 3, 2013
Creator: Drewes, Robert C.; Hillman, Stanley S.; Hedrick, Michael & Withers, Philip C.
Partner: UNT College of Arts and Sciences
open access

Exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice

Description: Article on the exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice.
Date: December 17, 2013
Creator: Oppenheim, Hannah A.; Lucero, JoAnn; Guyot, Anne-Cécile; Herbert, Lindsay M.; McDonald, Jacob D.; Mabondzo, Aloïse et al.
Partner: UNT College of Arts and Sciences
open access

Analysis of the Genome of a Korean Isolate of the Pieris rapae Granulovirus Enabled by Its Separation from Total Host Genomic DNA by Pulse-Field Electrophoresis

Description: Article on an analysis of the genome of a Korean isolate of the Pieris rapae granulovirus enabled by its separation from total host genomic DNA by pulse-field electrophoresis.
Date: December 31, 2013
Creator: Jo, Yong Hun; Patnaik, Bharat Bhusan; Kang, Se Won; Chae, Sung-Hwa; Oh, Seunghan; Kim, Dong Hyun et al.
Partner: UNT College of Arts and Sciences
open access

Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs

Description: Article on nutrient-deprivation autophagy factor-1 (NAF-1) and biochemical properties of a novel cellular target for anti-diabetic drugs.
Date: May 22, 2013
Creator: Tamir, Sagi; Zuris, John A.; Agranat, Lily; Lipper, Colin H.; Conlan, Andrea R.; Michaeli, Dorit et al.
Partner: UNT College of Arts and Sciences
open access

Resequencing of Treponema pallidum ssp. pallidum Strains Nichols and SS14: Correction of Sequencing Errors Resulted in Increased Separation of Syphilis Treponeme Subclusters

Description: Article on the resequencing of Treponema pallidum ssp. pallidum strains nichols and SS14 and how the correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters.
Date: September 10, 2013
Creator: Pĕtrošová, Helena; Pospíšilová, Petra; Strouhal, Michal; Čejková, Darina; Zobaníková, Marie; Mikalova, Lenka et al.
Partner: UNT College of Arts and Sciences
open access

Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs

Description: Article on nutrient-deprivation autophagy factor-1 (NAF-1) and biochemical properties of a novel cellular target for anti-diabetic drugs.
Date: May 22, 2013
Creator: Tamir, Sagi; Zuris, John A.; Agranat, Lily; Lipper, Colin H.; Conlan, Andrea R.; Michaeli, Dorit et al.
Partner: UNT College of Arts and Sciences
open access

Elemental Concentrations in the Seed of Mutants and Natural Variants of Arabidopsis thaliana Grown under Varying Soil Conditions

Description: Article on elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown under varying soil conditions.
Date: May 2013
Creator: McDowell, Stephen C.; Akmakjian, Garo; Sladek, Chris; Mendoza-Cózatl, David; Morrissey, Joe B.; Saini, Nick et al.
Partner: UNT College of Arts and Sciences
open access

Preliminary Assessment of Microbiome Changes Following Blood-Feeding and Survivorship in the Amblyomma americanum Nymph-to-Adult Transition using Semiconductor Sequencing

Description: Article on a preliminary assessment of microbiome changes following blood-feeding and survivorship in the Amblyomma americanum nymph-to-adult transition using semiconductor sequencing.
Date: June 20, 2013
Creator: Menchaca, Arturo C.; Visi, David K.; Strey, Otto F.; Teel, Pete D.; Kalinowski, Kevin E.; Allen, Michael S. et al.
Partner: UNT College of Arts and Sciences
open access

Garcinol, a Polyisoprenylated Benzophenone Modulates Multiple Proinflammatory Signaling Cascades Leading to the Suppression of Growth and Survival of Head and Neck Carcinoma

Description: Article on the constitutive activation of proinflammatory transcription factors such as STAT3 and NF-KB that play a pivotal role in the proliferation and survival of squamous cell carcinoma of the head and neck (HNSCC).
Date: June 26, 2013
Creator: Li, Feng; Shanmugam, Muthu K.; Chen, Luxi; Chatterjee, Snehajyoti; Basha, Jeelan; Kumar, Alan Prem et al.
Partner: UNT College of Arts and Sciences
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