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Syntheses of Antimetabolites

Description: In these studies several different types of antimetabolites were synthesized, and their biological effects were examined in various assay systems. More extensive investigations were done in microbial systems in which many of the compounds proved to be inhibitory to growth, and attempts were made to determine the mode of biochemical action by adding supplements of the appropriate natural metabolite.
Date: January 1970
Creator: Clifton, George Gil
Partner: UNT Libraries
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Synthesis of Certain Aminooxy Compounds

Description: The research described herein is concerned with the synthesis of certain organic compounds which have the amino-oxy grouping and are related in structure to the naturally occurring amines, putrescine, spermidine and spermine.
Date: January 1970
Creator: Lewis, Wassel Andrew
Partner: UNT Libraries
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Oxovanadium(IV) Complexes of Substituted N-(2-Thiophenyl)Salicylideneimine

Description: In an effort to study the spectral, magnetic, and stereochemical properties of vanadyl complexes, both a new series of vanadyl complexes derived from type (VII) ligands with subnormal magnetic moment and from type (VIII) ligands with normal magnetic moment are synthesized and characterized.
Date: June 1970
Creator: Lee, Cheng Chang
Partner: UNT Libraries
open access

ESR Studies of Group IV Substituted Anilines

Description: The purpose of the investigation described herein was to investigate the degree of delocalization of the unpaired electron in ion radicals formed in the oxidation process of compounds with aromatic rings connected by means of various groups and atoms not entering the ring; then, to establish the relationship of coupling constants in radical cations with substituent σ values. The parent cation radical, in which the co-planar ion was derived from N,N-dimethylaniline, was selected in order to maxi… more
Date: June 1970
Creator: Wong, Pui-Suen
Partner: UNT Libraries
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Synthesis of 1-Amino-2-Hydroxycyclopentanecarboxylic Acid

Description: This investigation involved the synthesis of 1-amino-2-hydroxycyclopentanecarboxylic acid, a potential structural analog of the natural amino acids, serine and threonine. The title compound also includes the structural features present in an established antitumor agent, cycloleucine.
Date: December 1970
Creator: Huddle, John David
Partner: UNT Libraries
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High Temperature Enthalpies of the Lead Halides: Enthalpies and Entropies of Fusion

Description: The objectives of this investigation were: 1. To establish calorimetrically the transition temperature for the orthorhombic to cubic transition exhibited by PbF₂ and to determine the enthalpy of this transition. 2. To determine if the solid-solid phase transitions claimed in the literature for PbCl₂, PbF₂, PbBr₂, and PbI₂ were of thermodynamic importance, and if so, to determine the enthalpies of transition. 3. To determine if the discontinuous thermal expansions reported by Hsu for the lead ha… more
Date: June 1970
Creator: Linsey, Clarence W.
Partner: UNT Libraries
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Ketene Carbodiimide Cycloadditions

Description: It was proposed to study the cycloaddition of ketenes and carbodiimides in some detail. The first objective was to investigate the general applicability of the reaction as a tool for the synthetic organic chemist in the preparation of a new class of substituted β-lactams; i.e., imino-β-lactams. It was proposed for this part of the research problem to look for the intermediate, either directly or indirectly, by trapping experiments. It was further proposed to study substituent effects in the ket… more
Date: August 1970
Creator: Dorsey, Edwin Darrell
Partner: UNT Libraries
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The Photolysis of Ethyllithium and Triethylaluminum

Description: The majority of interest in organolithium and organoaluminum compounds has centered around their potency as polymerization catalysts.
Date: January 1970
Creator: Brewer, Terry Lowell
Partner: UNT Libraries
open access

Ketene Reactions: I. The Addition of Acid Chlorides to Dimethylketene ; II. The Cycloaddition of Ketenes to Carbonyl Compounds

Description: Part I describes the addition of several acid chlorides to dimethylketene. The resulting 3-ketoacid chlorides were isolated and characterized. Part II describes the cycloaddition of several aldoketenes to chloral. The ketenes were generated in situ by dehydrohalogenation and dehalogenation of appropriately substituted acyl halides.
Date: December 1970
Creator: Smith, Larry
Partner: UNT Libraries
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Aromatic Amino Acid Studies

Description: Pyridine ring analogs of the aromatic amino acids phenylalanine and tyrosine were synthesized and studied in microbiological and mammalian systems.
Date: December 1970
Creator: Sullivan, Patrick Timothy
Partner: UNT Libraries
open access

Electrochemical Dissolution of ZnO Single Crystals

Description: The separation of oxidation-reduction reactions into individual half-cells with a resulting "mixed potential" is well known as a dissolution mechanism for metals; however, the mechanism by which non-conducting crystals lose ions to the solution has been studied only slightly.
Date: January 1970
Creator: Justice, David Dixon
Partner: UNT Libraries
open access

Reactions of N-(Substituted) Phthalimides with n-Alkylamines

Description: The initial purpose of this study was to determine if steric problems would account for the difference in the products obtained in the reaction of the N-(substituted)phthalimide with low and high molecular weight amines.
Date: August 1970
Creator: Johnson, D. Pat
Partner: UNT Libraries
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