Neuropharmacological Characteristics of Tolerance for Cocaine Used as a Discriminative Stimulus
Description:
The main purpose of this research was to investigate the phenomenon of tolerance to cocaine. Tolerance is operationally defined as a decreased drug effect due to prior history of drug administration. The animal model that was chosen to investigate tolerance to cocaine was the drug discrimination model, which is an animal analogue of human subjective drug effects. In the drug discrimination procedure, animals are trained to emit one behavior when injected with saline. In the present experimen…
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Date:
August 1987
Creator:
Wood, Douglas M. (Douglas Michael)
Partner:
UNT Libraries