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Growth regulation by macrophages

Description: The evidence reviewed here indicates that macrophages, either acting alone or in concert with other cells, influence the proliferation of multiple types of cells. Most of the data indicate that these effects are mediated by soluble macrophage-elaborated products (probably proteins) although the role of direct cell-to-cell contacts cannot be ruled out in all cases. A degree of success has been achieved on the biochemical characterization of these factors, due mainly to their low specific activit… more
Date: January 1, 1982
Creator: Wharton, W.; Walker, E. & Stewart, C.C.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Purification of phospholamban, a 22,000 dalton protein from cardiac sarcoplasmic reticulum that is specifically phosphorylated by cyclic AMP-dependent protein kinase

Description: Very low concentrations deoxycholate (DOC) were used to isolate two proteins from canine cardiac sarcoplasmic reticulum. These two proteins are phospholamban, a 22,000 dalton protein, and the Ca/sup 2 +/ + Mg/sup 2 +/-ATPase, the major protein of the sarcoplasmic reticulum, responsible for the active transport of calcium. The 22,000 dalton protein is first solubilized in a very low concentration of DOC and then subjected to column chromatography. After molecular weight sieving on a Sephadex G-7… more
Date: January 1, 1979
Creator: Bidlack, J. M. & Shamoo, A. E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Radiation effects and metalloproteins studied by x-ray photoelectron spectroscopy

Description: X-ray photoelectron spectroscopy (XPS) is used to study the bonding structure at the iron site of cytochrome c and the bonding of rare earth ions to the phosphate oxygens of ATP. Radiation effects are studied on several amino acid and simple peptide model systems. The emission spectrum of the x-ray source is calculated from literature references. The distributions of photon energy as a function of photon frequency and as a function of take-off angle are obtained. From these distributions, the r… more
Date: July 1, 1975
Creator: Wurzbach, J.A.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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The magnesium chelation step in chlorophyll biosynthesis

Description: The biogenesis of energy transducing membranes requires the coordinate synthesis of prosthetic groups, proteins and lipids. Two of the major prosthetic groups, chlorophyll and heme, share a common biosynthetic pathway that diverges at the point of metal insertion into protoporphyrin IX. Insertion of iron leads to heme, while insertion of magnesium leads to chlorophyll. The Mg-chelatase from intact cucumber chloroplasts has been characterized with regard to substrate specificity, regulation, ATP… more
Date: January 1, 1991
Creator: Weinstein, J.D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Regulation of cell division in higher plants

Description: Cell division is arguably the most fundamental of all developmental processes. In higher plants, mitotic activity is largely confined to foci of patterned cell divisions called meristems. From these perpetually embryonic tissues arise the plant's essential organs of light capture, support, protection and reproduction. Once an adequate understanding of plant cell mitotic regulation is attained, unprecedented opportunities will ensue for analyzing and genetically controlling diverse aspects of de… more
Date: January 1, 1992
Creator: Jacobs, T.W.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Nitrogen control of chloroplast development and differentiation

Description: The growth and development of plants and photosynthetic microorganisms is commonly limited by the availability of nitrogen. Our work concerns understanding the mechanisms by which plants and algae that are subjected to nitrogen deprivation alter the composition of photosynthetic membranes and enzymes involved in photosynthetic carbon metabolism. Toward these ends, we study biosynthetic and gene expression processes in the unicellular green alga Chlamydomonas reinhardtii which is grown in an amm… more
Date: December 1, 1991
Creator: Schmidt, G.W.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Molecular biological enhancement of coal biodesulfurization. [Rhodococcus]

Description: The objective of this project is to produce one or more microorganisms capable of removing the organic and inorganic sulfur in coal. The original specific technical objectives of the project were to: Clone and characterize the genes encoding the enzymes of the 4S'' pathway (sulfoxide/sulfone/sulfonate/sulfate) for release of organic sulfur from coal; Return multiple copies of genes to the original host to enhance the biodesulfurization activity of that organism; Transfer this pathway into a fas… more
Date: March 15, 1990
Creator: Litchfield, J. H.; Fry, I.; Wyza, R. E.; Palmer, D. T.; Zupancic, T. J. & Conkle, H. N.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Molecular biological enhancement of coal biodesulfurization. [Rhodococcus, thiobacillus]

Description: The objective of this project is to produce one or more microorganisms capable of removing the organic and inorganic sulfur in coal. The original specific technical objectives of the project were to: clone and characterize the genes encoding the enzymes of the 4S'' pathway (sulfoxide/sulfone/sulfonate/sulfate) for release of organic sulfur from coal; return multiple copies of genes to the original host to enhance the biodesulfurization activity of that organism; transfer this pathway into a fas… more
Date: June 14, 1990
Creator: Litchfield, J. H.; Fry, I.; Wyza, R. E.; Palmer, D. T.; Zupancic, T. J. & Conkle, H. N.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Biological production of organic solvents from cellulosic wastes. Progress report, September 15, 1976--September 14, 1977

Description: The objectives of this project are to optimize a modular process to convert cellulosic wastes to butanol and other oil-sparing chemicals. Research to date has focused on developing analytical methods, establishing a good data base and improving cellulase yields. Reliable assay methods for the Thermoactinomyces cellulase complex have been developed, measuring glucose and reducing sugar from filter paper and Avicel for total cellulase activity, viscosity change with carboxymethyl cellulose for th… more
Date: June 1, 1977
Creator: Pye, E.K.; Humphrey, A.E. & Forro, J.R.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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MSU-DOE Plant Research Laboratory

Description: This document is the compiled progress reports of research funded through the Michigan State University/Department of Energy Plant Research Laboratory. Fourteen reports are included, covering the molecular basis of plant/microbe symbiosis, cell wall biosynthesis and proteins, gene expression, stress responses, plant hormone biosynthesis, interactions between the nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and trafficking, regulation of lipid metabolis… more
Date: January 1, 1991
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Anaerobic bioprocessing of low-rank coals

Description: The overall goal of this project is to find biological methods to remove carboxylic functionalities from low-rank coals and to assess the properties of the modified coal towards coal liquefaction. The main objectives for this quarter were: (1) continuation of microbial consortia development and maintenance, (2) crude enzyme study using best decarboxylating organisms, (3) decarboxylation of lignite, demineralized Wyodak coal and model polymers, and (4) characterization of biotreated coals.
Date: April 15, 1992
Creator: Jain, M. K.; Narayan, R. & Han, O.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Interdisciplinary research and training program in the plant sciences

Description: This document is the compiled progress reports from the Interdisciplinary Research and Training Program in the Plant Sciences funded through the MSU-DOE Plant Research Laboratory. Fourteen reports are included, covering topics such as the molecular basis of plant/microbe symbiosis, cell wall proteins and assembly, gene expression, stress responses, growth regulator biosynthesis, interaction between nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and membr… more
Date: January 1, 1991
Creator: Wolk, C.P.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Harvard-MIT research program in short-lived radiopharmaceuticals

Description: This report presents research on radiopharmaceuticals. The following topics are discussed: antibody labeling with positron-emitting radionuclides; antibody modification for radioimmune imaging; labeling antibodies; evaluation of technetium acetlyacetonates as potential cerebral blood flow agents; and studies in technetium chemistry. (CBS)
Date: January 1, 1991
Creator: Adelstein, S.J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Synthetic inactivators of kallikrein

Description: Reagents were developed which bind covalently to side chains of kallikrein, thereby inactivating the enzyme. Both temporary and irreversible inhibitors have been synthesized. (ACR)
Date: January 1, 1981
Creator: Shaw, E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Molecular biology of Lea genes of higher plants

Description: This report contains our progress to date in determining the function of the D-7 Lea proteins in cotton embryos. We have completely sequenced the D-7 gene and established {ital E. coli} transformants which synthesize reasonable amounts of the D-7 protein. Two-dimensional electrophoresis was required to assay fractions for D-7 protein during purification to homogeneity, since D-7 has no known enzymatic activity, contains no Trp, and little Phe or Tyr, and {ital E. coli} has several proteins of s… more
Date: July 1, 1991
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Post transcriptional regulation of chloroplast gene expression by nuclear encoded gene products

Description: The following is a review of research accomplished in the first two years of funding for the above mentioned project. The work performed is a molecular characterization of nuclear mutants of Chlamydomonas reinhardtii which are deficient in different stages in the post-transcriptional expression of a single chloroplast encoded polypeptide, the D2 protein of Photosystem II. Our long-term goals are to understand the molecular mechanisms by which nuclear gene products affect the expression of chlor… more
Date: January 1, 1992
Creator: Kuchka, Michael R.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Molecular mechanisms of mutagenesis and carcinogenesis. Final report, November 1, 1978-October 31, 1979

Description: The recA gene product mediates induction of a battery of cellular functions in E. coli collectively known as the SOS inducible functions. These include prophage induction, induction of filamentous cell growth, induction of DNA repair systems and induction of the recA gene itself. Prophage induction has been demonstrated to result from cleavage of the phage repressor protein by a specific protease function of the recA protein. Such cleavage destroys repressor function in lysogenic cells and allo… more
Date: April 1, 1980
Creator: Ptashne, M.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Experimental Engineering Section semiannual progress report, March 1-August 31, 1976. Volume 2. Biotechnology and environmental programs

Description: This volume contains the progress report of the biotechnology and environmental programs in the Experimental Engineering Section of the Chemical Technology Division. Research efforts in these programs during this report period have been in five areas: (1) environmental research; (2) centrifugal analyzer development; (3) advanced analytical systems development; (4) bioengineering research; and (5) bioengineering development. Summaries of these programmatic areas are contained in Volume I.
Date: March 1, 1978
Creator: Pitt, Jr., W. W. & Mrochek, J. E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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