11 Matching Results

Search Results

Advanced search parameters have been applied.
in subjects: "Functionals"  
Results: 1 - 11
open access

Compensatory Paracrine Mechanisms That Define The Urothelial Response to Injury in Partial Bladder Outlet Obstruction

Description: Diseases and conditions affecting the lower urinary tract are a leading cause of dysfunctional sexual health, incontinence, infection, and kidney failure. The growth, differentiation, and repair of the bladder's epithelial lining are regulated, in part, by fibroblast growth factor (FGF)-7 and -10 via a paracrine cascade originating in the mesenchyme (lamina propria) and targeting the receptor for FGF-7 and -10 within the transitional epithelium (urothelium). The FGF-7 gene is located at the… more
Date: June 21, 2007
Creator: Bassuk, James; Lendvay, Thomas S.; Sweet, Robert; Han, Chang-Hee; Soygur, Tarkan; Cheng, Jan-Fang et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Community Land Model Version 3.0 (CLM3.0) Developer's Guide

Description: This document describes the guidelines adopted for software development of the Community Land Model (CLM) and serves as a reference to the entire code base of the released version of the model. The version of the code described here is Version 3.0 which was released in the summer of 2004. This document, the Community Land Model Version 3.0 (CLM3.0) User's Guide (Vertenstein et al., 2004), the Technical Description of the Community Land Model (CLM) (Oleson et al., 2004), and the Community Land M… more
Date: December 21, 2004
Creator: Hoffman, FM
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Short sequence motifs, overrepresented in mammalian conservednon-coding sequences

Description: Background: A substantial fraction of non-coding DNAsequences of multicellular eukaryotes is under selective constraint. Inparticular, ~;5 percent of the human genome consists of conservednon-coding sequences (CNSs). CNSs differ from other genomic sequences intheir nucleotide composition and must play important functional roles,which mostly remain obscure.Results: We investigated relative abundancesof short sequence motifs in all human CNSs present in the human/mousewhole-genome alignments vs. … more
Date: February 21, 2007
Creator: Minovitsky, Simon; Stegmaier, Philip; Kel, Alexander; Kondrashov,Alexey S. & Dubchak, Inna
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Disparate requirements for the Walker A and B ATPase motifs ofhuman RAD51D in homologous recombination

Description: In vertebrates, homologous recombinational repair (HRR) requires RAD51 and five RAD51 paralogs (XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D) that all contain conserved Walker A and B ATPase motifs. In human RAD51D we examined the requirement for these motifs in interactions with XRCC2 and RAD51C, and for survival of cells in response to DNA interstrand crosslinks. Ectopic expression of wild type human RAD51D or mutants having a non-functional A or B motif was used to test for complementation of a … more
Date: April 21, 2006
Creator: Wiese, Claudia; Hinz, John M.; Tebbs, Robert S.; Nham, Peter B.; Urbin, Salustra S.; Collins, David W. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Correlation Spectroscopy of Minor Species: Signal Purification and Distribution Analysis

Description: We are performing experiments that use fluorescence resonance energy transfer (FRET) and fluorescence correlation spectroscopy (FCS) to monitor the movement of an individual donor-labeled sliding clamp protein molecule along acceptor-labeled DNA. In addition to the FRET signal sought from the sliding clamp-DNA complexes, the detection channel for FRET contains undesirable signal from free sliding clamp and free DNA. When multiple fluorescent species contribute to a correlation signal, it is dif… more
Date: June 21, 2006
Creator: Laurence, T A; Kwon, Y; Yin, E; Hollars, C; Camarero, J A & Barsky, D
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Information Management Infrastructure for the Systematic Annotation of Vertebrate Genomes

Description: The primary accomplishment of the project has been the development of a functional genomics database system, GUS (Genomics Unified Schema). The system provides a relational schema, application framework, and web interface for multiple projects and includes information on sequences, gene expression, gene regulation, ontologies, and data provenance. The system has been made portable and has been set up at other institutions. A web site is available describing the system and providing links for do… more
Date: March 21, 2003
Creator: Stoeckert, Christian J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Impact of Drill and Blast Excavation on Repository Performance Confirmation

Description: There has been considerable work accomplished internationally examining the effects of drill and blast excavation on rock masses surrounding emplacement openings of proposed nuclear waste repositories. However, there has been limited discussion tying the previous work to performance confirmation models such as those proposed for Yucca Mountain, Nevada. This paper addresses a possible approach to joining the available information on drill and blast excavation and performance confirmation. The me… more
Date: August 21, 2000
Creator: Keller, R.; Francis, N.; Houseworth, J. & Kramer, N.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Radar Imaging of Spheres in 3D using MUSIC

Description: We have shown that multiple spheres can be imaged by linear and planar EM arrays using only one component of polarization. The imaging approach involves calculating the SVD of the scattering response matrix, selecting a subset of singular values that represents noise, and evaluating the MUSIC functional. The noise threshold applied to the spectrum of singular values for optimal performance is typically around 1%. The resulting signal subspace includes more than one singular value per sphere. Th… more
Date: January 21, 2003
Creator: Chambers, D H & Berryman, J G
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Simulations of highly reactive fluids

Description: We report density functional molecular dynamics simulations to determine the early chemical events of hot (T = 3000 K) and dense (1.97 g/cm{sup 3}, V/V{sub 0} = 0.68) nitromethane (CH{sub 3}NO{sub 2}). The first step in the decomposition process is an intermolecular proton abstraction mechanism that leads to the formation of CH{sub 3}NO{sub 2}H and the aci ion H{sub 2}CNO{sub 2}{sup -}, in support of evidence from static high-pressure and shock experiments. An intramolecular hydrogen transfer t… more
Date: July 21, 2005
Creator: Fried, L E; Manaa, M R & Reed, E J
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

STM-Induced Void Formation at the Al{sub 2}O{sub 3}/Ni{sub 3}Al(111) Interface

Description: Under UHV conditions at 300 K, the applied electric field and/or resulting current from an STM tip creates nanoscale voids at the interface between an epitaxial, 7.0 {angstrom} thick Al{sub 2}O{sub 3} film and a Ni{sub 3}Al(111) substrate. This phenomenon is independent of tip polarity. Constant current (1 nA) images obtained at +0.1 V bias and +2.0 bias voltage (sample positive) reveal that voids are within the metal at the interface and, when small, are capped by the oxide film. Void size inc… more
Date: September 21, 2000
Creator: Magtoto, N. P.; Niu, C.; Anzaldura, M.; Kelber, J. A. & Jennison, D. R.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Ab initio and density functional studies of hydrocarbon adsorption in zeolites.

Description: The adsorption energies of methane and ethane in zeolites are investigated with ab initio molecular orbital theory and density functional theory. In this work we have used zeolite cluster models containing two, three, and five tetrahedral (Si, Al) atoms and have found equilibrium structures for complexes of methane, ethane, and propane with an acid site. If a large enough cluster is used and correlation effects are included via perturbation theory, the calculated adsorption energy for ethane is… more
Date: August 21, 1998
Creator: Curtiss, L. A.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
Back to Top of Screen