12,753 Matching Results

Search Results

Advanced search parameters have been applied.

[Letter from Julia A. Barr to the Moore family, December 3, 1888]

Description: This item is from the Charles B. Moore Collection. It is written by Julia A. Barr, Henry and Charles Moore's cousin. In the letter, Julia updates the Moore family on the happenings in Jerseyville, Illinois and the news includes: a dialogue about meeting cousin George Wilson in Eureka Springs, Arkansas while on a trip there, a discussion about the people that accompanied here on the trip and how long she stayed, details concerning the people she meet in Eureka Springs, a conversation about Seella, her two children, and Polly, a dialogue about their helper who was discharged over a year ago and how they are getting along without him, an update on the bountiful crops and how good rain has made it possible for people to get out of debt, a discussion about "Aunt" Sally Smith and Uncle Abner's family, a dialogue about Sottie Knaff's daughter, details about the Goodrich family, an aside about the town of Jerseyville, a dialogue about Mrs. O. P. Powell's children, a discussion about Wilson Cross and Ida Barr Cross, details about Fannie and her love for entertaining, updates on family, a dialogue about Barr's California trip and the places they stopped at along the way, details about the trip and the cities and sites Barr saw in California, a discussion about the trip back home to Illinois and details about their stop in Salt Lake City, an aside on how lovely the topography was from Salt Lake to Denver, a discussion on her return home, and a dialogue about recent plans. She closes the letter by asking how Linnet was doing, asks the Moore family to write soon, and sends her love to all. The envelope is included with the letter.
Date: December 3, 1888
Creator: Barr, Julia A.
Partner: UNT Libraries Special Collections

Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science)

Description: This report describes three studies aimed at using radiolabeled pharmaceuticals to explore brain function and anatomy. The first section describes the chemical preparation of (F18)fluorinated benzamides (dopamine D-2 receptor tracers), (F18)fluorinated benzazepines (dopamine D-1 receptor tracers), and tissue distribution of (F18)-fluoxetine (serotonin reuptake site tracer). The second section relates pharmacological and behavioral studies of amphetamines. The third section reports on progress made with processing of brain images from CT, MRI and PET/SPECT with regards to brain metabolism of glucose during mental tasks.
Date: June 1, 1992
Creator: Cooper, M. & Beck, R. N.
Partner: UNT Libraries Government Documents Department

Vegetation uptake from burial ground alpha waste trenches

Description: This study was conducted as part of an evaluation of the potential radiological consequences of reinhabiting the SRS burial ground. The objective was to determine the uptake of buried, low-level, transuranic waste from unlined earthen trenches by forest vegetation. Two tree plots were established in 1979. One plot was put over a trench containing alpha waste and the other in an area without trenches. When the tree seedlings were sampled during 1979 and 1980, and analysized for {sup 239}Pu and {sup 238}Pu, there was only a small difference in radionuclude concentration between trees planted over the trench and those planted on the control plot because of the limited root intrusion into the trench by the seedlings. However, when trees were sample in 1986, 1987, and 1988 and analyzed for {sup 241}Am, {sup 238}Pu, {sup 239}Pu, and {sup 237}Np activity, the average activity of all of these isotopes was significantly higher over the trenches than in the control plot. These measurements indicate that tree roots will extract transuranic isotopes from buried, low-level waste. The amount of radioisotopes moved from the trenches to the surface is small and the level in the trees is low enough that dose from exposure will be small. The long term effects of transport of radioisotopes from the trenches to the surface soil was evaluated by estimating the accumulation in the surface soil. Transuranic activity in selected food crops was calculated using the soil activity and the literature derived concentration factors. In all cases, the activity of the transuranic isotopes in the edible portion of the plants was quite low. The activity in the leaf tissue was much higher than in the seed. However, it should be noted that in only one case was the activity higher than the naturally occurring activity of {sup 40}K in the ...
Date: January 1, 1989
Creator: Murphy, C. E. Jr. & Tuckfield, R. C.
Partner: UNT Libraries Government Documents Department

Toxicity assessment of Hanford Site wastes by bacterial bioluminescence. [Photobacter phosphoreum:a3]

Description: This paper examines the toxicity of the nonradioactive component of low-level wastes stored in tanks on the Hanford reservation. The use of a faster, cheaper bioassay to replace the 96 hour fish acute toxicity test is examined. The new bioassay is based on loss of bioluminescence of {und Photobacter phosphoreum} (commonly called Microtox) following exposure to toxic materials. This bioassay is calibrated and compares well to the standard fish acute toxicity test for characterization of Hanford Wastes. 4 refs., 11 figs., 11 tabs. (MHB)
Date: September 1, 1991
Creator: Rebagay, T.V.; Dodd, D.A. & Voogd, J.A.
Partner: UNT Libraries Government Documents Department

The development of in vitro mutagenicity testing systems using T-lymphocytes

Description: This annual report describes progress in studies on hprt mutations induced by radon or Indium 111 along with the corresponding mutation frequency, cloning and molecular spectra in human T-lymphocytes. Parallel studies on the mutation susceptibility between individuals is being investigated by hprt mutation studies on ataxia telangiectasia and xeroderma pigmentosum.
Date: May 1, 1993
Creator: Albertini, R.J.
Partner: UNT Libraries Government Documents Department

Testing methodologies

Description: Several methodologies are available for screening human populations for exposure to ionizing radiation. Of these, aberration frequency determined in peripheral blood lymphocytes is the best developed. Individual exposures to large doses can easily be quantitated, and population exposures to occupational levels can be detected. However, determination of exposures to the very low doses anticipated from a low-level radioactive waste disposal site is more problematical. Aberrations occur spontaneously, without known cause. Exposure to radiation induces no new or novel types, but only increases their frequency. The limitations of chromosomal aberration dosimetry for detecting low level radiation exposures lie mainly in the statistical signal to noise'' problem, the distribution of aberrations among cells and among individuals, and the possible induction of aberrations by other environmental occupational or medical exposures. However, certain features of the human peripheral lymphocyte-chromosomal aberration system make it useful in screening for certain types of exposures. Future technical developments may make chromosomal aberration dosimetry more useful for low-level radiation exposures. Other methods, measuring gene mutations or even minute changes on the DNA level, while presently less will developed techniques, may eventually become even more practical and sensitive assays for human radiation exposure. 15 refs.
Date: January 1, 1990
Creator: Bender, M.A.
Partner: UNT Libraries Government Documents Department

Nuclear Medicine Program progress report for quarter ending September 30, 1992

Description: The radioiodination and in vivo evaluation of p-iodocaramiphen a muscarinic antagonist which binds with high affinity to the M[sub 1] receptor subtype in vitro are described. Biodistribution studies in female Fischer rats demonstrated that [[sup 125]I]-piodocaraminphen had significant cerebral localization, but the uptake did not demonstrate specific uptake in those cerebral regions rich in muscarinic receptors, and radioactivity washed out rapidly from the brain. In addition there was no significant blockage of activity when the rats were preinjected with quinuclidinyl benzilate. These results suggest that p-iodocaramiphen is not a good candidate for the in vivo study of M[sub 1] muscarinic receptor populations by SPECT. Because of the widespread interest and expected importance of the availability of large amounts of tungsten-188 required for the tungsten-188/rhenium-188 generator systems, we have investigated the large-scale production of tungsten-188 in the ORNL HFIR. We have also compared our production data with the theoretical production values and with experimental data available in the literature from other reactors. Tungsten-188 is produced in a fission nuclear reactor by double neutron capture of tungsten-186. The experimental yield of tungsten-188 is approximately 4 mCi/mg of tungsten-186 at the end of bombardment (EOB) in the HFIR operating at 85 MWt power for a one cycle irradiation ([approximately]21 days) at a thermal neutron flux of 2 [times] 10[sup 15] n.s[sup [minus]1]cm[sup [minus]2].
Date: December 1, 1992
Creator: Knapp, F.F. Jr.; Ambrose, K.R.; Beets, A.L.; Callahan, A.P.; McPherson, D.W.; Mirzadeh, S. et al.
Partner: UNT Libraries Government Documents Department

Implementing a new TLD system

Description: Martin Marietta Energy Systems will soon be issuing new personnel dosimeters at four of their five Department of Energy (DOE) facilities, The Piketon, Ohio uranium enrichment facility is not included in this dosimetry upgrade program. This talk will focus on the ORNL perspective of this program, especially the new beta-gamma dosimeter. Neutron dosimetry will be discussed briefly. The objective of this upgrade is to put in place a state-of-the-art personnel dosimetry system and to meet the recent DOE Laboratory Accreditation Program performance criteria. Processing such a large number of dosimeters will require stringent quality controls. Approximately 18,000 beta-gamma dosimeters are scheduled for issue in January 1989. 15 figs.
Date: January 1, 1988
Creator: Rhea, T.A.
Partner: UNT Libraries Government Documents Department

Utilization of dose assessment models to facilitate off-site recovery operations for accidents at nuclear facilities

Description: One of the most important uses of dose assessment models in response to accidents at nuclear facilities is to help provide guidance to emergency response managers for identifying, and mitigating, the consequences of an accident once the accident has been terminated. By combining results from assessment models with radiological measurements, a qualitative methodology can be developed to aid emergency response managers in determining the total dose received by the population and to minimize future doses through the use of mitigation procedures. To illustrate the methodology, this discussion focuses on the use of models to estimate the dose delivered to the public both during and after a nuclear accident. 4 refs., 10 figs., 1 tab.
Date: September 1, 1989
Creator: Dickerson, M.H. & Foster, K.T.
Partner: UNT Libraries Government Documents Department

Radioactivity in consumer products

Description: Papers presented at the conference dealt with regulations and standards; general and biological risks; radioluminous materials; mining, agricultural, and construction materials containing radioactivity; and various products containing radioactive sources.
Date: August 1, 1978
Creator: Moghissi, A.A.; Paras, P.; Carter, M.W. & Barker, R.F. (eds.)
Partner: UNT Libraries Government Documents Department

Development of gamma-emitting, receptor binding radiotracers for imaging the brain and pancreas

Description: This progress report covers period from Nov. 1, 1989 to Aug. 31, 1990. The long term objective was to develop receptor-binding radiotracers for SPECT or PET imaging of CNS or peripheral nervous system. The specific chemistry aims, as understood on the basis of past findings, were: to synthesize and develop a more polar analogs of 4IQNB, possessing similar binding characteristics but eliminated more rapidly from the surrounding tissues and the target organ, to design a method of introducing a technetium chelating group onto a molecule or cholinergic agent without drastic lowering of its apparent affinity, to synthesize and develop radiotracers based on m-AChR antagonists selective for one of the subtypes of the receptor. The chemistry service aims were to prepare and characterize (R,R)- and (R,S)-4IQNB and derivatives, to provide the triazene intermediate to other investigators, and to provide ({sup 123}I)4IQNB for in vivo imaging. The biochemistry aims were to characterize the vitro and in vivo properties of novel compounds and to perform the pharmacokinetic studies. 3 refs., 5 tabs.
Date: January 1, 1990
Creator: Reba, R.C.
Partner: UNT Libraries Government Documents Department

Radionuclide deposition and exposure in the Federal Republic of Germany after the Chernobyl accident

Description: Analyses of air, water, and foodstuff samples, together with in situ gamma spectrometric measurements in the Federal Republic of Germany, have documented the deposition and exposure consequences of the Chernobyl accident. In some cases, exposure values are significantly higher than background levels. Data compiled for the period from the initial identification of excess atmospheric radioactivity to the present, represent a unique resource for testing and validating models of environmental transport and human exposure. These data will serve as the bases for future studies of organism response, both somatic and genetic, to nuclear radiation. They will also prove useful in suggesting modifications to environmental sampling and monitoring systems. 14 refs., 13 figs., 4 tabs.
Date: November 1, 1989
Creator: Winkelmann, I.; Haubelt, R.; Neumann, P.; Fields, D.E. (Bundesgesundheitsamt, Neuherberg (Germany, F.R.). Inst. fuer Strahlenhygiene & Oak Ridge National Lab., TN (USA))
Partner: UNT Libraries Government Documents Department