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Measuring Advances in HVAC Distribution System Design

Description: Substantial commercial building energy savings have been achieved by improving the performance of the HV AC distribution system. The energy savings result from distribution system design improvements, advanced control capabilities, and use of variable-speed motors. Yet, much of the commercial building stock remains equipped with inefficient systems. Contributing to this is the absence of a definition for distribution system efficiency as well as the analysis methods for quantifying performance. This research investigates the application of performance indices to assess design advancements in commercial building thermal distribution systems. The index definitions are based on a first and second law of thermodynamics analysis of the system. The second law or availability analysis enables the determination of the true efficiency of the system. Availability analysis is a convenient way to make system efficiency comparisons since performance is evaluated relative to an ideal process. A TRNSYS simulation model is developed to analyze the performance of two distribution system types, a constant air volume system and a variable air volume system, that serve one floor of a large office building. Performance indices are calculated using the simulation results to compare the performance of the two systems types in several locations. Changes in index values are compared to changes in plant energy, costs, and carbon emissions to explore the ability of the indices to estimate these quantities.
Date: May 1, 1998
Creator: Franconi, E.
Partner: UNT Libraries Government Documents Department

Effects on Occupants of Enhanced Particle Filtration in a non-problem office environment: A Double-Blind Crossover Intervention Study

Description: Workers in indoor environments often complain of symptoms, such as eye and nose irritation, headache, and fatigue, which improve away from work. Exposures causing such complaints, sometimes referred to as sick building syndrome, generally have not been identified. Evidence suggests these worker symptoms are related to chemical, microbiological, physical, and psychosocial exposures not well characterized by current methods. Most research in this area has involved cross-sectional studies, which are limited in their abilities to show causal connections. Experimental studies have also been conducted which, by changing one factor at a time to isolate its effects, can demonstrate benefits of an environmental intervention even before exposures or mechanisms are understood. This study was prompted by evidence that particulate contaminants may be related to acute occupant symptoms and discomfort. The objective was to assess, with a double-blind, double crossover intervention design, whether improved removal of small airborne particles by enhanced central filtration would reduce symptoms and discomfort.
Date: June 15, 1998
Creator: Mendell, M.J.; Fisk, W.J.; Petersen, M.; Hines, C.J.; Faulkner, D.; Deddens, J.A. et al.
Partner: UNT Libraries Government Documents Department

Predicting New Hampshire Indoor Radon Concentrations from geologic information and other covariates

Description: Generalized geologic province information and data on house construction were used to predict indoor radon concentrations in New Hampshire (NH). A mixed-effects regression model was used to predict the geometric mean (GM) short-term radon concentrations in 259 NH towns. Bayesian methods were used to avoid over-fitting and to minimize the effects of small sample variation within towns. Data from a random survey of short-term radon measurements, individual residence building characteristics, along with geologic unit information, and average surface radium concentration by town, were variables used in the model. Predicted town GM short-term indoor radon concentrations for detached houses with usable basements range from 34 Bq/m{sup 3} (1 pCi/l) to 558 Bq/m{sup 3} (15 pCi/l), with uncertainties of about 30%. A geologic province consisting of glacial deposits and marine sediments, was associated with significantly elevated radon levels, after adjustment for radium concentration, and building type. Validation and interpretation of results are discussed.
Date: May 1, 1998
Creator: Apte, M.G.; Price, P.N.; Nero, A.V. & Revzan, K.L.
Partner: UNT Libraries Government Documents Department

Potential Nationwide Improvements in Productivity and Health from Better Indoor Environments

Description: Theoretical considerations and empirical data suggest that existing technologies and procedures can improve indoor environments in a manner that significantly increases productivity and health. Existing literature contains moderate to strong evidence that characteristics of buildings and indoor environments significantly influence rates of respiratory disease, allergy and asthma symptoms, sick building symptoms, and worker performance. While there is considerable uncertainty in our estimates of the magnitudes of productivity gains that may be obtained by providing better indoor environments, the projected gains are very large. For the U.S., we estimate potential annual savings and productivity gains of $6 to $19 billion from reduced respiratory disease, $1 to $4 billion from reduced allergies and asthma, $10 to $20 billion from reduced sick building syndrome symptoms, and $12 to $125 billion from direct improvements in worker performance that are unrelated to health. In two example calculations, the potential financial benefits of improving indoor environments exceed costs by a factor of 8 and 14. Productivity gains that are quantified and demonstrated could serve as a strong stimulus for energy efficiency measures that simultaneously improve the indoor environment.
Date: May 1, 1998
Creator: Fisk, W.J. & Rosenfeld, A.H.
Partner: UNT Libraries Government Documents Department

Demonstration and Field Test of airjacket technology

Description: There are approximately 600,000 paint spray workers in the United States applying paints and coatings with some type of sprayer. Approximately 5% of these spray workers are in the South Coast Air Quality Management District (SCAQMD). These spray workers apply paints or other coatings to products such as bridges, houses, automobiles, wood and metal furniture, and other consumer and industrial products. The materials being sprayed include exterior and interior paints, lacquers, primers, shellacs, stains and varnishes. Our experimental findings indicate that the Airjacket does not significantly reduce the exposure of spray workers to paint fumes during HVLP spraying. The difference between ideal and actual spray paint procedures influence the mechanisms driving spray workers exposures to paint fumes and influence the viability of the Airjacket technology. In the ideal procedure, for which the Airjacket was conceived, the spray worker's exposure to paint fumes is due largely to the formation of a recirculating eddy between the spray worker and the object painted. The Airjacket ejects air to diminish and ventilate this eddy. In actual practice, exposures may result largely from directing paint upstream and from the bounce-back of the air/paint jet of the object being painted. The Airjacket, would not be expected to dramatically reduce exposures to paint fumes when the paint is not directed downstream or when the bounce-back of paint on the object creates a cloud of paint aerosols around the spray worker.
Date: June 1, 1998
Creator: Faulkner, D.; Fisk, W.J.; Gadgil, A.J. & Sullivan, D.P.
Partner: UNT Libraries Government Documents Department

Structural Formation Studies of UV-Catalyzed Gels and Aerogels byLight Scattering

Description: The skeletal structure of aerogel is determined before, during, and after the gel is formed. Supercritical drying of aerogel largely preserves the pore structure that is determined near the time of gelation. To better understand these gel formation mechanisms we carried out measurements of the time evolution of light scattering in a series of gels prepared without conventional acid or base catalysis. Instead, ultraviolet light was used to catalyze the formation of silica gels made from the hydrolysis of tetraethylorthosilicate and partly prehydrolyzed tetraethylorthosilicate in ethanol. Time evolution of light scattering provides information regarding the rate and geometrical nature of the assembly of the primary silica particles formed in the sol. UV-catalyzed gels show volumetric growth typical of acid-catalyzed gels, except when UV exposure is discontinued at the gel point, where gels then show linear chain formation typical of base-catalyzed gels. Long term UV exposure leads to coarsening of the pore network, a decrease in the clarity of the aerogel, and an increase in the surface area of the aerogel. Additionally, UV exposure up to the gel point leads to increased crystallinity in the final aerogel.
Date: April 1, 1998
Creator: Hunt, Arlon J. & Ayers, Michael R.
Partner: UNT Libraries Government Documents Department

Energy Savings in Refrigerated Walk-In Boxes

Description: The purpose of this technical brief is to provide an overview of the results of an assessment of a technique for saving energy in refrigerated walk-in coolers, and to evaluate the potential for this technology in Federal facilities. The focus of this study was on a single manufacturer of the technology, Nevada Energy Control Systems, Inc. (Necsi); no other vendors for this technology could be found. Previous studies were inconclusive about the overall efficacy of this technique due to uncertainties in a number of areas. [1] Previous evaluations also lacked the benefit of the results from recent manufacturer sponsored tests and did not address some fundamental issues about the overall efficacy of this technology that are critical to understanding its potential. The primary objective of this assessment was to determine if the previous studies combined with recent vendor sponsored test results substantiate the manufacturer's claims that this is a cost effective energy saving technique with significant potential in Federal facilities. Secondary objectives included evaluation of intangible benefits such as equipment life and reliability issues, and humidity and airflow effects on product.
Date: June 1, 1998
Creator: Webster, Tom
Partner: UNT Libraries Government Documents Department

A Sealed-Accelerator-Tube Neutron Generator for Boron Neutron Capture Therapy Application

Description: Radio-frequency (RF) driven ion sources are being developed in Lawrence Berkeley National Laboratory (LBNL) for sealed-accelerator-tube neutron generator applications. By using a 2.5-cm-diameter RF-driven multicusp source and a computer designed 100 keV accelerator column, peak extractable hydrogen current exceeding 1 A from a 3-mm-diameter aperture, together with H{sup +} yields over 94% have been achieved. These experimental findings together with recent moderator design will enable one to develop compact 14 MeV neutron generators based on the D-T fusion reaction. In this new neutron generator, the ion source, the accelerator and the target are all housed in a sealed metal container without pumping. With a 120 keV and 1 A deuteron beam, it is estimated that a treatment time of {approx} 45 minutes is needed for boron neutron capture therapy.
Date: June 1, 1998
Creator: Leung, K.-N.; Leung, K.N.; Lee, Y.; Verbeke, J.M.; Vurjic, J.; Williams, M.D. et al.
Partner: UNT Libraries Government Documents Department

Neutron Tube Design Study for Boron Neutron Capture TherapyApplication

Description: Radio-frequency (RF) driven ion sources are being developed in Lawrence Berkeley National Laboratory (LBNL) for sealed-accelerator-tube neutron generator application. By using a 5-cm-diameter RF-driven multicusp source H{sup +} yields over 95% have been achieved. These experimental findings will enable one to develop compact neutron generators based on the D-D or D-T fusion reactions. In this new neutron generator, the ion source, the accelerator and the target are all housed in a sealed metal container without external pumping. Recent moderator design simulation studies have shown that 14 MeV neutrons could be moderated to therapeutically useful energy ranges for boron neutron capture therapy (BNCT). The dose near the center of the brain with optimized moderators is about 65% higher than the dose obtained from a typical neutron spectrum produced by the Brookhaven Medical Research Reactor (BMRR), and is comparable to the dose obtained by other accelerator-based neutron sources. With a 120 keV and 1 A deuteron beam, a treatment time of {approx}35 minutes is estimated for BNCT.
Date: January 4, 1998
Creator: Verbeke, J.M.; Lee, Y.; Leung, K.N.; Vujic, J.; Williams, M.D.; Wu, L.K. et al.
Partner: UNT Libraries Government Documents Department

Beam Comissioning of the PEP-II High Energy Ring

Description: The PEP-II High Energy Ring (HER), a 9 GeV electron storage ring, has been in commissioning since spring 1997. Initial beam commissioning activities focused on systems checkout and commissioning and on determining the behavior of the machine systems at high beam currents. This phase culminated with the accumulation of 0.75 A of stored beam-sufficient to achieve design luminosity--in January 1998 after 3.5 months of beam time. Collisions with the 3 GeV positron beam of the Low Energy Ring (LER) were achieved in Summer of 1998. At high beam currents, collective instabilities have been seen. Since then, commissioning activities for the HER have shifted in focus towards characterization of the machine and a rigorous program to understand the machine and the beam dynamics is presently underway.
Date: November 12, 1998
Creator: Wienands, U.; Anderson, S.; Assmann, R.; Bharadwaj, V.; Cai, Y.; Clendenin, J. et al.
Partner: UNT Libraries Government Documents Department

Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus

Description: What determines the nuclear organization within a cell and whether this organization itself can impose cellular function within a tissue remains unknown. To explore the relationship between nuclear organization and tissue architecture and function, we used a model of human mammary epithelial cell acinar morphogenesis. When cultured within a reconstituted basement membrane (rBM), HMT-3522 cells form polarized and growth-arrested tissue-like acini with a central lumen and deposit an endogenous BM. We show that rBM-induced morphogenesis is accompanied by relocalization of the nuclear matrix proteins NuMA, splicing factor SRm160, and cell cycle regulator Rb. These proteins had distinct distribution patterns specific for proliferation, growth arrest, and acini formation, whereas the distribution of the nuclear lamina protein, lamin B, remained unchanged. NuMA relocalized to foci, which coalesced into larger assemblies as morphogenesis progressed. Perturbation of histone acetylation in the acini by trichostatin A treatment altered chromatin structure, disrupted NuMA foci, and induced cell proliferation. Moreover, treatment of transiently permeabilized acini with a NuMA antibody led to the disruption of NuMA foci, alteration of histone acetylation, activation of metalloproteases, and breakdown of the endogenous BM. These results experimentally demonstrate a dynamic interaction between the extracellular matrix, nuclear organization, and tissue phenotype. They further show that rather than passively ref lecting changes in gene expression, nuclear organization itself can modulate the cellular and tissue phenotype.
Date: August 14, 1998
Creator: Lelie'vre, S.A.; Weaver, V.M.; Nickerson, J.A.; Larabell, C.A.; Bhaumik, A.; Petersen, O.W. et al.
Partner: UNT Libraries Government Documents Department

Three dimensional field calculations for a Short Superconducting Dipole for the UCLA Ultra Compact Synchrotron

Description: The Ultra Compact Synchrotron (UCS), proposed for UCLA, is a compact 1.5 GeV electron light source with superconducting magnets to produce X rays with a critical energy of about 10 keV. The design physical length (cold length) for the dipole is 418 mm. The synchrotron requires that a uniform field be produced in a region that is 180 mm wide by 40 mm high by about 380 mm long. The end regions of the dipole should be short compared to the overall length of the dipole field region. A Vobly H type of dipole was selected for the synchrotron bending magnets. In order for each dipole to bend a 1.5 GeV electron beam 30 degrees, the central induction must be in the range of 6.4 to 6.9 T (depending on the dipole magnetic length). The pole width for the dipole was set so that over 90% of the X rays generated by the magnet can be extracted. The three dimensional field calculations were done using TOSCA. This report shows that a Vobly type of dipole will behave magnetically as a conventional water cooled iron dominated dipole. The uniformity of the integrated magnetic field can be controlled by varying the current in the shield coil with respect to the gap and cross-over coils. The two dimensional field in the center of the magnet can be tuned to be very uniform over a width of 110 to 120 mm. The three dimensional calculations show that the magnetic length along a particle track in the dipole is about 29 mm longer than the length of the iron pole pieces. This report will present the three dimensional design of the UCS Vobly dipole and the results of the field calculations for that magnet.
Date: August 1, 1998
Creator: Green, M.A. & Taylor, C.E.
Partner: UNT Libraries Government Documents Department

Nb3Sn Magnets for a Muon Collider

Description: High field dipole and quadrupole magnet designs with racetrack coils are investigated. The design option is particularly attractive for a muon collider dipole magnet using the Nb{sub 3}Sn superconductor. A conceptual design of {approx} 15 T single aperture dipole magnet is presented where the coils maintain a simple 2-d structure through the ends. The use of racetrack coils in quadrupole magnets is also discussed. It appears that the racetrack coils are less attractive for high gradient quadrupole magnets.
Date: June 20, 1998
Creator: Gupta, R.C.; Green, M.A.; Scanlan, R.M. & Palmer, R.
Partner: UNT Libraries Government Documents Department

Communication Between the Cell Membrane and the Nucleus: Role of Protein Compartmentalization

Description: Understanding how the information is conveyed from outside to inside the cell is a critical challenge for all biologists involved in signal transduction. The flow of information initiated by cell-cell and cell-extracellular matrix contacts is mediated by the formation of adhesion complexes involving multiple proteins. Inside adhesion complexes, connective membrane skeleton (CMS) proteins are signal transducers that bind to adhesion molecules, organize the cytoskeleton, and initiate biochemical cascades. Adhesion complex-mediated signal transduction ultimately directs the formation of supramolecular structures in the cell nucleus, as illustrated by the establishment of multi complexes of DNA-bound transcription factors, and the redistribution of nuclear structural proteins to form nuclear subdomains. Recently, several CMS proteins have been observed to travel to the cell nucleus, suggesting a distinctive role for these proteins in signal transduction. This review focuses on the nuclear translocation of structural signal transducers of the membrane skeleton and also extends our analysis to possible translocation of resident nuclear proteins to the membrane skeleton. This leads us to envision the communication between spatially distant cellular compartments (i.e., membrane skeleton and cell nucleus) as a bidirectional flow of information (a dynamic reciprocity) based on subtle multilevel structural and biochemical equilibria. At one level, it is mediated by the interaction between structural signal transducers and their binding partners, at another level it may be mediated by the balance and integration of signal transducers in different cellular compartments.
Date: October 21, 1998
Creator: Lelievre, Sophie A & Bissell, Mina J
Partner: UNT Libraries Government Documents Department

A High Field Magnet Design for A Future Hadron Collider

Description: US high energy physics community is exploring the possibilities of building a Very Large Hadron Collider (VLHC) after the completion of LHC. This paper presents a high field magnet design option based on Nb{sub 3}Sn technology. A preliminary magnetic and mechanical design of a 14-16 T, 2-in-1 dipole based on the 'common coil design' approach is presented. The computer code ROXIE has been upgraded to perform the field quality optimization of magnets based on the racetrack coil geometry. A magnet R&D program to investigate the issues related to high field magnet designs is also outlined.
Date: September 1, 1998
Creator: Gupta, R.; Chow, K.; Dietderich, D.; Gourlay, S.; Millos, G.; McInturff, A. et al.
Partner: UNT Libraries Government Documents Department

Reciprocal interactions between Beta1-integrin and epidermal growth factor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology

Description: Anchorage and growth factor independence are cardinal features of the transformed phenotype. Although it is logical that the two pathways must be coregulated in normal tissues to maintain homeostasis, this has not been demonstrated directly. We showed previously that down-modulation of {beta}1-integrin signaling reverted the malignant behavior of a human breast tumor cell line (T4-2) derived from phenotypically normal cells (HMT-3522) and led to growth arrest in a threedimensional (3D) basement membrane assay in which the cells formed tissue-like acini (14). Here, we show that there is a bidirectional cross-modulation of {beta}1-integrin and epidermal growth factor receptor (EGFR) signaling via the mitogenactivated protein kinase (MAPK) pathway. The reciprocal modulation does not occur in monolayer (2D) cultures. Antibodymediated inhibition of either of these receptors in the tumor cells, or inhibition of MAPK kinase, induced a concomitant downregulation of both receptors, followed by growth-arrest and restoration of normal breast tissue morphogenesis. Crossmodulation and tissue morphogenesis were associated with attenuation of EGF-induced transient MAPK activation. To specifically test EGFR and {beta}1-integrin interdependency, EGFR was overexpressed in nonmalignant cells, leading to disruption of morphogenesis and a compensatory up-regulation of {beta}1-integrin expression, again only in 3D. Our results indicate that when breast cells are spatially organized as a result of contact with basement membrane, the signaling pathways become coupled and bidirectional. They further explain why breast cells fail to differentiate in monolayer cultures in which these events are mostly uncoupled. Moreover, in a subset of tumor cells in which these pathways are misregulated but functional, the cells could be 'normalized' by manipulating either pathway.
Date: September 30, 1998
Creator: Wang, F.; Weaver, V.M.; Petersen, O.W.; Larabell, C.A.; Dedhar, S.; Briand, P. et al.
Partner: UNT Libraries Government Documents Department

Fabrication and Test Results for Rutherford-Type Cables Made from BSCCO Strands

Description: Wires based on the Bi-2212 HTS superconductor are becoming available commercially, with current densities that are attractive for some applications. We report here on our success in using these Bi-2212 wires to fabricate multistrand, kiloamp conductors that can be used to construct dipole and quadrupole magnets for particle accelerator applications. Multistrand cables have been made from several types of Bi-2212 wire supplied by two manufacturers. These cables were made with cores of various compositions and dimensions in order to optimize the fabrication process. In addition, cables have been made from aspected strands as well as round strands. Cable critical currents will be reported and compared for the various cable parameters investigated in this study.
Date: September 1, 1998
Creator: Scanlan, R.M.; Dietderich, D.R.; Higley, H.C.; Marken, K.R.; Motowidlo, L.R.; Solokowski, R. et al.
Partner: UNT Libraries Government Documents Department

Fabrication and Test Results of a Prototype, Nb3Sn Superconducting Racetrack Dipole Magnet

Description: A prototype, Nb{sub 3}Sn superconducting magnet, utilizing a racetrack coil design has been built and tested. This magnet represents the first step in a recently implemented program to develop a high field, accelerator quality magnet. This magnet was constructed with coils wound from conductor developed for the ITER project, limiting the magnet to a field of 6-7 Tesla. Subsequent magnets in the program will utilize improved conductor, culminating in a magnet design capable of producing fields approaching 15 Tesla. The simple geometry is more suitable for the use of brittle superconductors necessary to eventually reach high field levels. In addition, fewer and simpler parts are used in fabricating these coils compared with the more conventional cosine theta cross section coils. The general fabrication steps, mechanical design and quench performance are discussed.
Date: September 1, 1998
Creator: Gourlay, S. A.; Chow, K.; Dietderich, D.R.; Gupta, R.; Hannaford, R.; Harnden, W. et al.
Partner: UNT Libraries Government Documents Department

Critical Current of Superconducting Rutherford Cable in High Magnetic Fields with Transverse Pressure

Description: For high energy physics applications superconducting cables are subjected to large stresses and high magnetic fields during service. It is essential to know how these cables perform in these operating conditions. A loading fixture capable of applying loads of up to 700 kN has been developed by NHMFL for LBNL. This fixture permits uniform loading of straight cables over a 122 mm length in a split-pair solenoid in fields up to 12 T at 4.2 K. The first results from this system for Rutherford cables of internal-tin and modified jelly roll strand of Nb{sub 3}Sn produced by IGC and TWC showed that little permanent degradation occurs up to 210 MPa. However, the cable made from internal-tin strand showed a 40% reduction in K{sub c} at 11T and 210 MPa while a dable made from modified jelly roll material showed only a 15% reduction in I{sub c} at 11T and 185 MPa.
Date: September 1, 1998
Creator: Dietderich, D.R.; Scanlan, R.M.; Walsh, R.P. & Miller, J.R.
Partner: UNT Libraries Government Documents Department

Design and Fabrication of Racetrack Coil Accelerator Magnets

Description: Most accelerator magnets for applications in the field range up to 9 T utilize NbTi superconductor and a cosine theta coil design. For fields above 9 T, it is necessary to use Nb{sub 3}Sn or other strain sensitive materials, and other coil geometries that are more compatible with these materials must be considered. This paper describes their recent efforts to design a series of racetrack coil magnets that will provide experimental verification of this alternative magnet design for a dual aperture dipole magnet with the goal of reaching a field level of 15 T, will be described. The experimental program, which consists of a series of steps leading to a high field accelerator quality magnet, will be presented. Fabrication of a racetrack dipole magnet utilizing Nb{sub 3}Sn superconductor and a wind and react approach will be presented.
Date: November 11, 1998
Creator: Chow, K.; Dietderich, D.R.; Gourlay, S.A.; Gupta, R.; Harnden, W.; Lietzke, A. et al.
Partner: UNT Libraries Government Documents Department

A Conceptual Design of Transport Lines for a Heavy-Ion Inertial-Fusion Power Plant

Description: Two groups of heavy-ion beam pulses are to be transported from an induction linear accelerator to a target in an inertial fusion power plant. A group of 20 prepulses arrives first, emerging at lower energy upstream from the linac exit; the second group, of forty main pulses, have full energy. For definiteness they use numerical values for these beams developed by Wayne Meier; both beams consist of singly charged ions with mass number 200, having prepulse and main pulse energies of 3 GeV and 4 Gev, respectively.
Date: November 2, 1998
Creator: Heimbucher, Lynn
Partner: UNT Libraries Government Documents Department