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Formation, Stability, and Mobility of One-Dimensional Lipid Bilayer on High Curvature Substrates

Description: Curved lipid membranes are ubiquitous in living systems and play an important role in many biological processes. To understand how curvature and lipid composition affect membrane formation and fluidity we have assembled and studied mixed 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine (DOPC) and 1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine (DOPE) supported lipid bilayers on amorphous silicon nanowires with controlled diameters ranging from 20 nm to 200 nm. Addition of cone-shaped DOPE molecules to cy… more
Date: March 23, 2007
Creator: Huang, J.; Martinez, J.; Artyukhin, A.; Sirbuly, D.; Wang, Y.; Ju, J. W. et al.
Partner: UNT Libraries Government Documents Department
open access

Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates

Description: We present one-dimensional (1-D) lipid bilayer structures that integrate carbon nanotubes with a key biological environment-phospholipid membrane. Our structures consist of lipid bilayers wrapped around carbon nanotubes modified with a hydrophilic polymer cushion layer. Despite high bilayer curvature, the lipid membrane maintains its fluidity and can sustain repeated damage-recovery cycles. We also present the first evidence of spontaneous insertion of pore-forming proteins into 1-D lipid bilay… more
Date: July 23, 2004
Creator: Artyukhin, Alexander; Shestakov, Alexei; Harper, Jennifer; Bakajin, Olgica; Stroeve, Pieter & Noy, Aleksandr
Partner: UNT Libraries Government Documents Department
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