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Alternative Coca Reduction Strategies in the Andean Region

Description: This report identifies opportunities for and constraints to reducing Andean coca production through: 1) improving U.S. alternative development efforts and 2) applying biological control technology (bio-control) to eradicate illegally produced coca.
Date: July 1993
Creator: United States. Congress. Office of Technology Assessment.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

The American College of nuclear physicians 18th annual meeting and scientific sessions DOE day: Substance abuse and nuclear medicine abstracts

Description: Despite the enormous personal and social cost Of substance abuse, there is very little knowledge with respect to the mechanisms by which these drugs produce addiction as well as to the mechanisms of toxicity. Similarly, there is a lack of effective therapeutic intervention to treat the drug abusers. In this respect, nuclear medicine could contribute significantly by helping to gather information using brain imaging techniques about mechanisms of drug addiction which, in turn, could help design … more
Date: February 1, 1992
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Analysis of volatile organic compounds from illicit cocaine samples

Description: Detection of illicit cocaine hydrochloride shipments can be improved if there is a greater understanding of the identity and quantity of volatile compounds present. This study provides preliminary data concerning the volatile organic compounds detected in a limited Set of cocaine hydrochloride samples. In all cases, cocaine was one of the major volatile compounds detected. Other tropeines were detected in almost all samples. Low concentrations of compounds that may be residues of processing sol… more
Date: July 1, 1994
Creator: Robins, W. H. & Wright, B. W.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Associated-particle sealed-tube neutron probe: Detection of explosives, contraband, and nuclear materials

Description: Continued research and development of the APSTNG shows the potential for practical field use of this technology for detection of explosives, contraband, and nuclear materials. The APSTNG (associated-particle sealed-tube generator) inspects the item to be examined using penetrating 14-MeV neutrons generated by the deuterium-tritium reaction inside a compact accelerator tube. An alpha detector built into the sealed tube detects the alpha-particle associated with each neutron emitted in a cone enc… more
Date: May 1, 1996
Creator: Rhodes, E. & Dickerman, C.E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Brain imaging studies of the cocaine addict: Implications for reinforcement and addiction

Description: These studies document dopaminergic abnormalities in cocaine abusers. They also suggest a regulatory role of Dopamine (DA) in frontal metabolism. The correlation of striatal D{sub 2} receptor availability with metabolism was strongest for orbital frontal cortex (OFC) cingulate and prefrontal cortices. In cocaine abusers tested during early withdrawal (<1 week) the OFC was found to be hypermetabolic and metabolism in OFC and prefrontal cortices were found to be significantly associated with coca… more
Date: July 1, 1995
Creator: Volkow, N. D. & Fowler, J. S.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Development, implementation and management of a drug testing program in the workplace

Description: To combat the rising use of drugs in the workplace many American companies have implemented drug testing programs and are testing employees and job applicants for use of illegal drugs. In addition, on September 15, 1986, Executive Order No.12564 was issued by President Reagan, which requires all federal agencies to develop programs and policies, one of the goals of which is to achieve a drug-free federal workplace. Included in this Executive Order is the requirement that federal agencies implem… more
Date: January 1, 1990
Creator: Burtis, C.A.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Development of a portable preconcentrator/ion mobility spectrometer system for the trace detection of narcotics

Description: This project was supported by LDRD funding for the development and preliminary testing of a portable narcotics detection system. The system developed combines a commercial trace detector known as an ion mobility spectrometer (IMS) with a preconcentrator originally designed by Department 5848 for the collection of explosives molecules. The detector and preconcentrator were combined along with all necessary accessories onto a push cart, thus yielding a fully portable detection unit. Preliminary t… more
Date: August 1, 1997
Creator: Parmeter, John E. & Custer, Chad A.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Discriminative Stimulus Properties of Cocaine: Tolerance and Cross-Tolerance Characteristics

Description: Rats were trained to discriminate an injection of cocaine, 5.0 mg/kg, from an injection of saline, using a two-lever choice paradigm: one lever was correct after cocaine injection, the other lever was correct after a saline injection. After training, cocaine and methamphetamine were generalized to the cocaine lever, but phenethylamine (PEA) was only partially generalized. Cocaine was injected every 8 hrs, 20.0 mg/kg, and the discriminability of 5.0 mg/kg was tested every other day. Redetermina… more
Date: May 1985
Creator: Wood, Douglas M. (Douglas Michael)
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Federal Cocaine Sentencing Disparity: Sentencing Guidelines, Jurisprudence, and Legislation

Description: This report discusses legislation and several court cases to examine the changing nature of Crack Cocaine penalties in comparison to powder cocaine. Until 2005, the Guidelines were binding on federal courts: the judge had discretion to sentence a defendant, but only within the narrow sentencing range that the Guidelines provided. In its 2005 opinion United States v. Booker, the Supreme Court declared that the Guidelines must be considered advisory rather than mandatory, in order to comply with … more
Date: August 5, 2010
Creator: Yeh, Brian T.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Fiber optic detector

Description: This invention is comprised of a portable fiber optic detector that senses the presence of specific target chemicals by exchanging the target chemical for a fluorescently-tagged antigen that is bound to an antibody which is in turn attached to an optical fiber. Replacing the fluorescently-tagged antigen reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.
Date: December 31, 1990
Creator: Partin, J. K.; Ward, T. E. & Grey, A. E.
Item Type: Refine your search to only Patent
Partner: UNT Libraries Government Documents Department
open access

Fitness for duty in the nuclear power industry. Volume 3, Annual summary of program performance reports, CY 1992

Description: This report summarizes the data from the semi-annual reports on fitness-for-duty programs submitted to the NRC by 52 utilities for two reporting periods: January 1 through June 30, 1992, and July 1 through December 31, 1992. During 1992, licensees reported that they had conducted 266,551 tests for the presence of illegal drugs and alcohol. Of these test, 1,818 (.68%) were confirmed positive. Positive test results varied by category of test and category of worker. The majority of positive test r… more
Date: July 1, 1993
Creator: Fleming, T.; Westra, C.; Field, I.; Forslund, C.; Durbin, N.; Grant, T. et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Gene by Disease Interaction on Orbitofrontal Gray Matter in Cocaine Addiction

Description: Chronic cocaine use has been associated with structural deficits in brain regions having dopamine receptive neurons. However, the concomitant use of other drugs and common genetic variability in monoamine regulation present additional structural variability. We therefore examined variations in gray matter volume (GMV) as a function of lifetime drug use and the monoamine oxidase A (MAOA) genotype in cocaine use disorders (CUD) and healthy controls.
Date: December 5, 2010
Creator: Alia-Klein, N.; Alia-Klein, N.; Parvaz, M. A.; Woicik, P. A.; Konova, A.; Maloney, T. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Habit-Forming Agents: Their Indiscriminate Sale and Use a Menace to the Public Welfare

Description: Report discussing the growth of drug addiction in the United States due chiefly to the consumption of drugs originally intended for medicinal purposes. Soothing syrups, soft drinks, medications for the nose and lungs, and remedies for headaches and epilepsy are the primary sources of habit-forming substances. In addition, medicines purporting to cure tobacco and drug addiction have, in many cases, also been found to contain addictive agents.
Date: 1910
Creator: Kebler, Lyman F. (Lyman Frederic), b. 1863
Item Type: Refine your search to only Pamphlet
Partner: UNT Libraries Government Documents Department
open access

MicroCantilever (MC) based nanomechanical sensor for detection of molecular interactions

Description: Specific aims of this study are to investigate the mechanism governing surface stress generation associated with chemical or molecular binding on functionalized microcantilevers. Formation of affinity complexes on cantilever surfaces leads to charge redistribution, configurational change and steric hindrance between neighboring molecules resulting in surface stress change and measureable cantilever deformation. A novel interferometry technique employing two adjacent micromachined cantilevers (a… more
Date: May 11, 2011
Creator: Kang, Kyung
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries Government Documents Department
open access

Myocardial uptake of cocaine and effects of cocaine on myocardial substrate utilization and perfusion in hypertensive rats

Description: Cocaine abuse is a problem causing world-wide concern and the number of deaths following cocaine use is increasing. Cardiovascular complications following cocaine include severe tachyarrythmias, pulmonary edema, myocardial infarction, and acute renal failure, which are major problems confronting emergency facilities. While the studies of cocaine effects on the brain have been given the most attention, it is clear that the effects of cocaine on the cardiovascular system are of great importance, … more
Date: January 1, 1992
Creator: Som, P.; Wang, G. J.; Oster, Z. H.; Knapp, F. F. Jr.; Yonekura, Y.; Fujibayashi, Y. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Myocardial uptake of cocaine and effects of cocaine on myocardial substrate utilization and perfusion in hypertensive rats

Description: Cocaine abuse is a problem causing world-wide concern and the number of deaths following cocaine use is increasing. Cardiovascular complications following cocaine include severe tachyarrythmias, pulmonary edema, myocardial infarction, and acute renal failure, which are major problems confronting emergency facilities. While the studies of cocaine effects on the brain have been given the most attention, it is clear that the effects of cocaine on the cardiovascular system are of great importance, … more
Date: December 31, 1992
Creator: Som, P.; Wang, G. J.; Oster, Z. H.; Knapp, F. F. Jr.; Yonekura, Y.; Fujibayashi, Y. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Neurochemical mechanisms underlying responses to psychostimulants

Description: This study employed positron emission tomography (PET) to investigate biochemical and metabolic characteristics of the brain of individuals which could put them at risk for drug addiction. It takes advantage of the normal variability between individuals in response to psychoactive drugs to investigate relation between mental state, brain neurochemistry and metabolism and the behavioral response to drugs. We discuss its use to assess if there is an association between mental state and dompaminer… more
Date: November 1, 1994
Creator: Volkow, N. D.; Fowler, J. S.; Hitzemann, R. & Wang, G. J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Neuropharmacological Characteristics of Tolerance for Cocaine Used as a Discriminative Stimulus

Description: The main purpose of this research was to investigate the phenomenon of tolerance to cocaine. Tolerance is operationally defined as a decreased drug effect due to prior history of drug administration. The animal model that was chosen to investigate tolerance to cocaine was the drug discrimination model, which is an animal analogue of human subjective drug effects. In the drug discrimination procedure, animals are trained to emit one behavior when injected with saline. In the present experimen… more
Date: August 1987
Creator: Wood, Douglas M. (Douglas Michael)
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

New developments in APSTNG neutron probe diagnostics

Description: The development and investigation of a small associated-particle sealed-tube neutron generator (APSTNG) show potential to allow the associated-particle diagnostic method to be moved out of the laboratory into field applications. The APSTNG interrogates the inspected object with 14-MeV neutrons generated from the deuterium-tritium reaction and detects the alpha-particle associated with each neutron inside a cone encompassing the region of interest. Gamma-ray spectra of resulting neutron reaction… more
Date: December 1995
Creator: Rhodes, E. & Dickerman, C. E.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

A new proof-of-principle contraband detection system

Description: A new concept for a CDS has been developed under a Phase I ARPA funded program; it uses gamma resonance absorption (GRA) to detect certain illegal drugs that may be transported in man-portable containers. A high detection probability for heroin and cocaine is possible with a device that is also searching for explosives. Elemental detection of both N and Cl is utilized, and with tomography, a 3D density image of the elements is generated. Total density image is also developed. These two together… more
Date: December 1, 1995
Creator: Sredniawski, J. J.; Debiak, T.; Kamykowski, E.; Rathke, J.; Schmor, P.; Altman, A. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
captions transcript

[News Clip: Baby Follow Up]

Description: Video footage from the KXAS-TV/NBC station in Fort Worth, Texas, to accompany a news story.
Date: May 21, 1993, 10:00 p.m.
Duration: 1 minute 41 seconds
Creator: KXAS-TV (Television station : Fort Worth, Tex.)
Item Type: Refine your search to only Video
Partner: UNT Libraries Special Collections
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