Glucose Metabolite Patterns as Markers of Functional Differentiation in Freshly Isolated and Cultured Mouse Mammary Epithelial Cells
Description:
In the mammary gland of nonruminant animals, glucose is utilized in a characteristic and unique way during lactation. We have measured the incorporation of glucose carbon from [U-{sup 14}C] glucose into intermediary metabolites and metabolic products in mammary epithelial cells from virgin, pregnant, and lactating mice and demonstrate that glucose metabolite patterns can be used to recognize stages of differentiated function. For these cells, the rates of synthesis of glycogen and lactose, the …
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Date:
June 1, 1980
Creator:
Emerman, J. T.; Bartley, J. C. & Bissell, M. J.
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UNT Libraries Government Documents Department