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Biological Effects of Radiation, and Related Biochemical and Physical Studies : Semiannual Progress Report [for] Period May 1, 1959 - October 31, 1959

Description: Progress reports from four divisions are included: (1) Division of Biophysics; (2) Division of Clinical Investigation; (3) Division of Nucleoprotein Chemistry; and (4) Radiochemistry Section.
Date: December 1, 1959
Creator: Denues, Arthur Russell Taylor, 1914-
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Seeing in the Light: Using Expansion Microscopy to Achieve Super-Resolution in Transmitted Light

Description: Light microscopy is inherently limited in resolution by properties of light such as diffraction and interference to 170-250 nm. Expansion microscopy is a quickly-developing method which achieves super-resolution by using a swellable hydrogel to physically expand biological samples themselves, rather than depending on the properties of fluorophores. This thesis demonstrates that expansion microscopy is a feasible means for achieving super-resolution in transmitted light microscopy modes. Though … more
Date: December 2022
Creator: Migliore, Julia R.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Computational Modeling of Cancer-Related Mutations in DNA Repair Enzymes Using Molecular Dynamics and Quantum Mechanics/Molecular Mechanics

Description: This dissertation details the use of computational methods to understand the effect that cancer-related mutations have on proteins that complex with nucleic acids. Firstly, we perform molecular dynamics (MD) simulations of various mutations in DNA polymerase κ (pol κ). Through an experimental collaboration, we classify the mutations as more or less active than the wild type complex, depending upon the incoming nucleotide triphosphate. From these classifications we use quantum mechanics/molecula… more
Date: May 2022
Creator: Leddin, Emmett Michael
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
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Biology Division Semiannual Progress Report for Period Ending February 15, 1956

Description: Progress report of the Oak Ridge National Laboratory Biology Division providing updates on various projects, experiments, and other work. This report includes a summary of scholarly output from the division and departmental activities in cytology and genetics, mammalian genetics and development, microbial protection and recovery, mammalian recovery, pathology and physiology, general physiology, biochemistry, enzymology and photosynthesis, microbiology, plant biochemistry, and biophysics.
Date: April 20, 1956
Creator: Hollaender, Alexander & Carson, Stanley F.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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The Development of Potential Therapeutic Anti-Myosin S2 Peptides that Modulate Contraction and Append to the Heart Homing Adduct Tannic Acid without Noticeable Effect on Their Functions

Description: This dissertation aimed to explore the S2 region with an attempt to modulate its elasticity in order to tune the contraction output. Two peptides, the stabilizer and destabilizer, showed high potential in modifying the S2 region at the cellular level, thus they were prepared for animal model testing. In this research, (i) S2 elasticity was studied, and the stabilizer and destabilizer peptides were built to tune contraction output through modulating S2 flexibility; (ii) the peptides were attache… more
Date: May 2021
Creator: Qadan, Motamed
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
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Structural and Functional Studies of TRPV6 Channels

Description: Presentation on TRPV6, which is an entry channel for calcium ions in epithelial cells, and its associated risk for cancer when overexpressed. It was presented at the UNT Transdisciplinary Conference on Ancestral Genomics Research which was held virtually on November 20-21, 2020.
Date: November 21, 2020
Duration: 25 minutes 24 seconds
Creator: Sobolevsky, Alexander
Item Type: Refine your search to only Video
Partner: University of North Texas
captions transcript

Genodynamics: Novel Biophysical Metrics for Assessing Single Nucleotide Polymorphisms in Ancestral Genomics Research

Description: This presentation highlights the work of the Whole Genome Science Foundation, Inc. which looks at single nucleotide polymorphisms (SNPs) through the lens of biophysics and provides a unique perspective on ancestral genomics. It was presented at the UNT Transdisciplinary Conference on Ancestral Genomics Research which was held virtually on November 20-21, 2020.
Date: November 20, 2020
Duration: 35 minutes 26 seconds
Creator: Dunston, Georgia M.
Item Type: Refine your search to only Video
Partner: University of North Texas
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Argonne National Laboratory Biology Division Quarterly Report: August to October, 1946

Description: From introductory paragraph: "This is the first quarterly report of the Biology Division of the Argonne National Laboratory. During the three-month period covered by this report, a large share of the time of many investigators has been spent in collating work done under the Biology Section of the Metallurgical laboratory for publication in the Plutonium Project Record. The large amount of work done under wartime pressure has made this, as in other divisions and projects, an important part of th… more
Date: November 21, 1946
Creator: Bruss, Austin M.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Pacific Northwest Laboratory annual report for 1989 to the DOE (Department of Energy) Office of Energy Research - Part 4: Physical Sciences

Description: This 1989 Annual Report from Pacific Northwest Laboratory (PNL) to the US Department of Energy (DOE) describes research in environment, safety, and health conducted during fiscal year 1989. The report again consists of five parts, each in a separate volume. This volume contains 20 papers. Part 4 of the Pacific Northwest Laboratory Annual Report of 1989 to the DOE Office of Energy Research includes those programs funded under the title Physical and Technological Research.'' The Field T… more
Date: April 1, 1990
Creator: Toburen, L. H.; Stults, B. R. & Mahaffey, J. A.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Theoretical Division annual report, FY 1975. [LASL]

Description: This report presents an overview of the activities in the Theoretical Division and a summary of research highlights during FY 1975. It is intended to inform a wide audience about the theoretical work of the LASL and, therefore, contains introductory material which places recent advances in a broader context. The report is organized into two special interest reports: reactor safety research and the Advanced Research Committee, and 11 reports from the T-Division group leaders on the work of their… more
Date: February 1, 1976
Creator: Carruthers, Peter A.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Joint Research Report for 1974--1975

Description: A general progress report is given on the research being carried out in the Biophysics Laboratory of the IIT Department of Physics and the Department of Medical Physics at Michael Reese Medical Center on pulse radiolysis experiments.
Date: April 1, 1976
Creator: Laboratories of Radiation Biology and Biophysics
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Life sciences: Lawrence Berkeley Laboratory, 1988

Description: Life Sciences Research at LBL has both a long history and a new visibility. The physics technologies pioneered in the days of Ernest O. Lawrence found almost immediate application in the medical research conducted by Ernest's brother, John Lawrence. And the tradition of nuclear medicine continues today, largely uninterrupted for more than 50 years. Until recently, though, life sciences research has been a secondary force at the Lawrence Berkeley Laboratory (LBL). Today, a true multi-program lab… more
Date: July 1, 1989
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Genes and gene expression: Localization, damage and control -- A multi-level and interdisciplinary study. Progress report, February 1, 1992--January 31, 1993

Description: This progress report describes gains made in three projects entitled (1) 3-Dimensional nuclear topography of genes and chromosomes in interphase nuclei, (2) Sequence specific identification and perturbation of the genomic DNA in living cells by nonionic oligonucleotide analogs (Matagen), and Resolution and isolation of specific DNA restriction fragments.(DT)
Date: August 1, 1992
Creator: Ts`o, P. O. P.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Protein folding and protein metallocluster studies using synchrotron small angler X-ray scattering

Description: Proteins, biological macromolecules composed of amino-acid building blocks, possess unique three dimensional shapes or conformations which are intimately related to their biological function. All of the information necessary to determine this conformation is stored in a protein`s amino acid sequence. The problem of understanding the process by which nature maps protein amino-acid sequences to three-dimensional conformations is known as the protein folding problem, and is one of the central unso… more
Date: June 1, 1994
Creator: Eliezer, D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Studies of DNA supercoiling in vivo and in vitro

Description: This thesis describes a number of diverse experiments whose common theme is to elaborate some aspect of DNA supercoiling. The torsion elastic constant of DNA is measure as a function of superhelix density using the technique of picosecond Time Resolved Fluorescence Polarization Anisotropy (FPA) of intercalated ethidium bromide. The results agree with theories which predict that the anisotropy decay should vary with the square root of the relative viscosity. This experiment furthermore demonstra… more
Date: October 1, 1990
Creator: Cook, D. N.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries Government Documents Department
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A new approach to calculate the hydration of DNA molecules

Description: A new method to calculate approximate water density distributions around DNA is presented. Formal and computational simplicity are emphasized in order to allow routine hydration studies. The method is based on the application of pair and triplet correlation functions of water-oxygen calculated by computer simulation. These correlation functions are combined with the configurational data of the electronegative atoms on DNA (oxygen and nitrogen) taken from crystal structures. For three B-DNA stru… more
Date: September 1, 1993
Creator: Hummer, G. & Soumpasis, D. M.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Exploratory Research and Development Fund, FY 1990. Report on Lawrence Berkeley Laboratory

Description: The Lawrence Berkeley Laboratory Exploratory R&D Fund FY 1990 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of an Exploratory R&D Fund (ERF) planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The research areas covered in this report are: Accelerator… more
Date: May 1, 1992
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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The Radiological Research Accelerator Facility. Progress report, December 1, 1993--November 30, 1994

Description: This document begins with a general description of the facility to include historical and up-to-date aspects of design and operation. A user`s guide and a review of research using the facility follows. Next the accelerator utilization and operation and the development of the facilities is given. Personnel currently working at the facility are listed. Lastly, recent publications and literature cited are presented.
Date: April 1, 1994
Creator: Hall, E. J. & Marino, S. A.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Physics Division progress report, January 1, 1993--December 31, 1993

Description: This report discusses its following topics: Recent Weapons-Physics Experiments on the Pegasus II Pulsed Power Facility; Operation of a Large-Scale Plasma Source Ion Implantation Experiment; Production of Charm and Beauty Mesons at Fermilab Sudbury Neutrino Observatory; P-Division`s Essential Role in the Redirected Inertial Confinement Fusion Program; Trident Target Physics Program; Comparative Studies of Brain Activation with Magnetocephalography and Functional Magnetic Resonance Imaging; Cellu… more
Date: July 1, 1994
Creator: Hollen, G. Y. & Schappert, G. T.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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A physico-chemical study of some areas of fundamental significance to biophysics. Three-year comprehensive report, 1989--1992

Description: This report discusses the following topics on Biophysics: Radiation signatures; electronic structure of steroids and vitamins; laser optogalvanic effect; vacuum ultraviolet spectroscopy; and ozone.
Date: April 30, 1992
Creator: McGlynn, S. P. & Kumar, D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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A physico-chemical study of some areas of fundamental significance to biophysics. Annual report, 1991--1992

Description: This report discusses the following topics: Radiation signatures; photoelectron spectroscopy of biologically active molecules; laser optogalvanic effect; magnetic circular dichroism; photochemistry of halogenated molecules; and density effects on high-n rydbergs.
Date: April 30, 1992
Creator: McGlynn, S. P. & Kumar, D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Applications of photon-in, photon-out spectroscopy with third-generation, synchrotron-radiation sources

Description: This report discusses the following topics: Mother nature`s finest test probe; soft x-ray emission spectroscopy with high-brightness synchrotron radiation sources; anisotropy and polarization of x-ray emission from atoms and molecules; valence-hole fluorescence from molecular photoions as a probe of shape-resonance ionization: progress and prospects; structural biophysics on third-generation synchrotron sources; ultra-soft x-ray fluorescence-yield XAFS: an in situ photon-in, photon-out spectros… more
Date: December 31, 1991
Creator: Lindle, D. W. & Perera, R. C. C.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Radiation physics, biophysics, and radiation biology. Progress report, December 1, 1991--November 30, 1992

Description: The following research programs from the Center for Radiological Research of Columbia University are described: Design and development of a new wall-less ultra miniature proportional counter for nanodosimetry; some recent measurements of ionization distributions for heavy ions at nanometer site sizes with a wall-less proportional counter; a calculation of exciton energies in periodic systems with helical symmetry: application to a hydrogen fluoride chain; electron energy-loss function in polynu… more
Date: May 1, 1992
Creator: Hall, E. J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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