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Quantitative Studies of Inhibitors of ADP-ribosylation in Vitro and in Vivo

Description: Article evaluating the selectivity of compounds originally identified as inhibitors of poly(ADP-ribose) polymerase on members of the three classes of enzymes. The results suggest that micromolar levels of the benzamides in the culture medium should allow selective inhibition of poly(ADP-ribose) metabolism in intact cells. Furthermore, comparative quantitative inhibition studies should prove useful for assigning the biological effects of these inhibitors as an effect on either poly(ADP-ribose) o… more
Date: March 15, 1989
Creator: Rankin, Patrick W.; Jacobson, Elaine L.; Benjamin, Robert C.; Moss, Joel & Jacobson, Myron K.
Partner: University of North Texas
open access

sup 13 C NMR investigation of crosslinking in organic aerogels

Description: Organic aerogels are a special type of low density foam produced from the supercritical drying of resorcinol-formaldehyde (RF) gels. These aerogels have continuous porosity, ultrafine cell/pore sizes (<1000 {angstrom}), and a microstructure composed of interconnected colloidal-like particles with diameters ranging from 30-175 {angstrom}. The particle size, surface area, density, and mechanical properties of the aerogels are largely determined by the catalysts concentration used in the sol-ge… more
Date: September 15, 1989
Creator: Ward, R. L. & Pekala, R. W.
Partner: UNT Libraries Government Documents Department
open access

Use of robotic systems for radiochemical sample changing and for analytical sample preparation

Description: Two uses of the Perkin-Elmer (PE) robotic system will be presented. In the first, a PE robot functions as an automatic sample changer for up to five low energy photon spectrometry (LEPS) detectors operated with a Nuclear Data ND 6700 system. The entire system, including the robot, is controlled by an IBM PC-AT using software written in compiled BASIC. Problems associated with the development of the system and modifications to the robot will be presented. In the second, an evaluation study was p… more
Date: May 15, 1989
Creator: Delmastro, J. R.; Hartenstein, S. D. & Wade, M. A.
Partner: UNT Libraries Government Documents Department
open access

Effects of irradiation on intergranular stress corrosion cracking of Type 304 stainless steel

Description: Constant extension rate tests (CERT) were run on ten irradiated specimens in continuation of a study of environmental effects on intergranular stress corrosion cracking of type 304 stainless steel. Specimens of both furnace sensitized and annealed material were irradiated to fluences of 1 to 2 {times} 10{sup 21} neutrons (E {ge} 0.1 Mev) per square centimeter at a temperature of {approximately}150{degree}C in a reflector position of the High Flux Isoptope Reactor at ORNL. CERT test conditions d… more
Date: September 15, 1989
Creator: Caskey, G. R.; Ondrejcin, R. S.; Aldred, P.; Davis, R. B. & Wilson, S. A.
Partner: UNT Libraries Government Documents Department
open access

High energy density fusing using the Compact Torus

Description: My remarks are concerned with employing the Compact Torus magnetic field configuration to produce fusion energy. In particular, I would like to consider high energy density regimes where the pressures generated extend well beyond the strength of materials. Under such conditions, where nearby walls are vaporized and pushed aside each shot, the technological constraints are very different from usual magnetic fusion and may admit opportunities for an improved fusion reactor design. 5 refs., 3 figs. more
Date: February 15, 1989
Creator: Hartman, C. W.
Partner: UNT Libraries Government Documents Department
open access

Pilot-scale production of dicesium hexachloroplutonate (Cs/sub 2/PuCl/sub 6/) and filtrate recovery

Description: The Rocky Flats Plant is introducing the use of dicesium hexachloroplutonate (DCHP) into the Molten Salt Extraction Process (MSE). DCHP (Cs/sub 2/PuCl/sub 6/) extracts americium from molten plutonium metal into a molten calcium chloride matrix. The DCHP is produced by precipitating plutonium (IV) from hydrochloric acid with cesium chloride. Before production of the DCHP began, we performed a pilot-scale test to determine yields, track impurities, and test filtrate recovery for the proposed proc… more
Date: March 15, 1989
Creator: Muscatello, A. C.; Stevens, J. R.; Killion, M. E.; Valdez, J. D. & Ames, R. L.
Partner: UNT Libraries Government Documents Department
open access

High average-power induction linacs

Description: Induction linear accelerators (LIAs) are inherently capable of accelerating several thousand amperes of /approximately/ 50-ns duration pulses to > 100 MeV. In this paper we report progress and status in the areas of duty factor and stray power management. These technologies are vital if LIAs are to attain high average power operation. 13 figs.
Date: March 15, 1989
Creator: Prono, D. S.; Barrett, D.; Bowles, E.; Caporaso, G. J.; Chen, Yu-Jiuan; Clark, J. C. et al.
Partner: UNT Libraries Government Documents Department
open access

Solar opacities constrained by solar neutrinos and solar oscillations

Description: This review discusses the current situation for opacities at the solar center, the solar surface, and for the few million kelvin temperatures that occur below the convection zone. The solar center conditions are important because they are crucial for the neutrino production, which continues to be predicted about 4 times that observed. The main extinction effects there are free-free photon absorption in the electric fields of the hydrogen, helium and the CNO atoms, free electron scattering of ph… more
Date: August 15, 1989
Creator: Cox, A. N.
Partner: UNT Libraries Government Documents Department
open access

Detailed photonuclear cross-section calculations and astrophysical applications

Description: We have investigated the role of an isomeric state and its coupling to the ground state (g.s.) via photons and neutron inelastic scattering in a stellar environment by making detailed photonuclear and neutron cross-section calculations for /sup 176/Lu and /sup 210/Bi. In the case of /sup 176/Lu, the g.s. would function as an excellent galactic slow- (s-) process chronometer were it not for the 3.7-h isomer at 123 keV. Our calculations predicted much larger photon cross sections for production o… more
Date: June 15, 1989
Creator: Gardner, D. G.; Gardner, M. A. & Hoff, R. W.
Partner: UNT Libraries Government Documents Department
open access

Effects of irradiation on intergranular stress corrosion cracking of Type 304 stainless steel

Description: Constant extension rate tests (CERT) were run on ten irradiated specimens in continuation of a study of environmental effects on intergranular stress corrosion cracking of type 304 stainless steel. Specimens of both furnace sensitized and annealed material were irradiated to fluences of 1 to 2 {times} 10{sup 21} neutrons (E {ge} 0.1 Mev) per square centimeter at a temperature of {approximately}150{degree}C in a reflector position of the High Flux Isoptope Reactor at ORNL. CERT test conditions d… more
Date: September 15, 1989
Creator: Caskey, G. R.; Ondrejcin, R. S. (Westinghouse Savannah River Co., Aiken, SC (United States)); Aldred, P.; Davis, R. B. & Wilson, S. A. (General Electric Co., San Jose, CA (United States))
Partner: UNT Libraries Government Documents Department
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