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Testing rare variants for hypertension using family-based tests with different weighting schemes

This paper proposes 4 weighting schemes for the family-based rare variants test (FBAT-v) to test for the effects of both rare and common variants across the genome.

Date: October 18, 2016

Creator: Wang, Xuexia; Zhao, Xingwang & Zhou, Jin

Partner: UNT College of Arts and Sciences

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A novel statistical method for rare-variant association studies in general pedigrees

In this paper, the authors discuss a novel statistical method for rare-variant association studies in general pedigrees for quantitative traits. This method uses a retrospective view that treats the traits as fixed and the genotypes as random, which accounts for complex and undefined ascertainment of families.

Date: October 18, 2016

Creator: Zhu, Huanhuan; Wang, Zhenchuan; Wang, Xuexia & Sha, Qiuying

Partner: UNT College of Arts and Sciences

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Testing rare variants for hypertension using family-based tests with different weighting schemes

A novel statistical method for rare-variant association studies in general pedigrees