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A Study of Synthesis and Stereoisomerism of some Complex Cobalt Compounds

Description: The purpose of this investigation is two-fold. Some new complex compounds, where one of the bidentate molecules is an optically active amino acid, were prepared, and attempts to separate those complex isomers by different methods were made. The replacement of the amino acids by optically inactive ligands was studied.
Date: January 1965
Creator: Yuan, Daniel T. N.
Partner: UNT Libraries

The Crystal and Molecular Structures of Tri-(p-Fluorophenyl)-Amine and Tri-(p-Iodophenyl)-Amine

Description: Because of the need for data on the geometry of nitrogen in arylamines, the determination of the crystal and molecular structures of tri-(p-fluorophenyl)-amine (TFPA) and tri-(p-iodophenyl)-amine (TIPA) was undertaken as the subject of this dissertation.
Date: January 1970
Creator: Freeman, Gerald R. (Gerald Richard)
Partner: UNT Libraries

Nuclear Magnetic Resonance Spectra of Some 1,2,4-triazoles

Description: In the work undertaken here, NMR has been used to ascertain the structure of some 1,2,4-triazoles. The investigation provides information concerning the structure of potentially tautomeric triazoles such as hydroxy- and aminotriazole. Connected with this aspect of triazole chemistry is the larger problem of mesohydric tautomerism. The present study also yields information for a comparison of substituent effects in triazoles, N-heteroaromatic substances and benzene.
Date: January 1967
Creator: Creagh, Linda Truitt
Partner: UNT Libraries

Selective Lipid Absorption

Description: An experiment was designed to study in the same animal any preferential absorption of a free fatty acid in the presence of a triglyceride of the same fatty acid. Rats were administered a mixture of free fatty acid and its triglyceride labeled with carbon-13 and carbon-14 respectively. Each isotope in the fed lipid and in the lipid recovered from the gastrointestinal tract was measured. The isotope effect, if any, was studied by administering a mixture of palmitic acid-1-C13 and palmitic acid-1-C14.
Date: January 1960
Creator: Marcia, John Albion
Partner: UNT Libraries

A Study of the Friedel-Craft Reactions of Phenolic Ethers

Description: The original purpose of this investigation was to prepare a series of diketones. However, since considerable difficulty was encountered in the preparation of these diketones, attention was shifted to a study of the Friedel-Craft reactions of phenolic ethers and to the reaction between phenolic ethers and dicarboxylic acids with boron trifluoride as a catalyst.
Date: January 1959
Creator: Roberson, Charles Ray
Partner: UNT Libraries

Preparation of N-Substituted Hydroxylamines from Oxaziridines

Description: In many series of compounds, intensity of biological activity and chemical reactivity are proportional. Generally whenever a alkyl group replaces a reactive hydrogen atom, as would be the case for an N-substituted hydroxylamine as compared to hydroxylamine, the over-all biological activity of the resulting compound is lower than that of its nonalkylated analogue. Since toxicity and physiological activity are not proportional, this comparison can only suggest possible types of derivatives to prepare and test.
Date: January 1968
Creator: Truitt, Sharon G.
Partner: UNT Libraries

The Adsorption of Radioactive Isotopes on Precipitates

Description: This thesis concerns the investigation of radioisotopes as indicators for precipitation reactions. As a precipitate forms in the presence of a radioisotope, adsorption may take place on its surface. If this adsorption changes markedly at the stoichiometric point it will be possible to use this variation as an indicator for the reaction.
Date: January 1954
Creator: Bulloch, Newman Payne
Partner: UNT Libraries

Hydantoins as Anticonvulsants. VIII. 5-Alkylmercapto Derivatives of 3-Methyl-5-Phenylhydantoin

Description: Recent years have seen a rapid increase in the search for new compounds to be employed in the treatment of convulsions associated with epilepsy and related ailments. The properties desired are a higher degree of effectiveness and lower toxicity than those already in use. This thesis describes the effect of methylation of the 5-alkylmercapto-5-phenylhydantoins.
Date: January 1954
Creator: Dick, Clarence Reinhardt
Partner: UNT Libraries

Hydantoins as Anticonvulsants. VI. 5-Substituted-Alkoxy Derivatives of 5-Phenylhydantoin

Description: No derivatives of 5-phenylhydantoin with an oxygen atom attached directly in the five position of the hydantoin nucleus have been found in the literature. It was therefore considered of interest to synthesize a series of compounds of this type to determine the effect of the change of the position of the oxygen atom on anticonvulsant activity.
Date: January 1954
Creator: Hoffman, James Rucker
Partner: UNT Libraries

Barbituric Acids. VII. 5-alkyl-derivatives of 5-ethoxy-barbituric Acid

Description: A great deal of research has been devoted in recent years to the search for new drugs for the treatment of epilepsy and related convulsive disorders. This emphasis is occasioned by the fact that no one drug is effective for all patients, and also by the fact that the toxicity of a drug varies considerably from one patient to another. Among the most effective drugs are certain members of the hydantoin and barbituric acid series. For some time there has been in progress in this laboratory an investigation of members of these two series in which a hetro atom attached directly to the hetrocyclic nucleus is introduced into the side chain at position five of these two series.
Date: January 1955
Creator: Hyde, Harold Wayne
Partner: UNT Libraries

Organomagnesium Compounds in Benzene Solvent and Their Application in Synthesis of Organoberyllium Compounds

Description: The work reported by D. Bryce-Smith and G. F. Cox, along with several recent publications describing experimental results designed to elucidate the long disputed question of the structure of the Grignard reagent in ether stimulated the work reported here, in an effort to obtain additional evidence of the structure of the organomagnesium complex in benzene solvent. Since the primary objective of this work was to prepare organoberyllium compounds using the organomagnesium complexes in hydrocarbon solvents, it seemed an insight into the structure of these complexes would be beneficial in this work. The techniques used and experimental evidence obtained from the structure elucidation of the ethereal Grignard reagent have been most helpful in organization of the methods used to study the structure of organomagnesium halide complexes in benzene solvent. It seemed that an insight into the structure of these organomagnesium halide complexes in hydrocarbon solvents would be beneficial in accomplishing the second objective of this work. This objective was to prepare organoberyllium compounds using the organomagnesium halide complexes prepared in hydrocarbon solvents.
Date: January 1966
Creator: Selman, Charles M.
Partner: UNT Libraries